Actifed Plus Suspension

Paracetamol (125mg)+ Triprolidine (0.625mg)+ Phenylpropanolamine (6.25mg)

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Actifed Plus Suspension is used in the treatment of common cold symptoms like runny nose, stuffy nose, sneezing, watery eyes and congestion or stuffiness. It also helps in relieving pain and fever.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 23 Jan 2026 | 11:47 PM (IST)

₹22.1 MRP ₹26.8318% off

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General Information

Contains

Paracetamol (125mg)+ Triprolidine (0.625mg)+ Phenylpropanolamine (6.25mg)

Marketer

Glaxo SmithKline Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Actifed Plus Suspension is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are nausea, allergic reaction, high blood pressure, and insomnia. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It can cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.

Never support self-medication or recommend your medicine to another person. It is beneficial to have plenty of fluids while taking this medication. Before taking it, you should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you. Pregnant or breastfeeding women should also consult their doctor.

Uses of Actifed Plus Suspension

Treatment of Common cold

Benefits of Actifed Plus Suspension

Treatment of Common cold
Actifed Plus Suspension is a combination medicine that effectively relieves symptoms of the common cold, such as a blocked nose, runny nose, watery eyes, sneezing, and congestion or stuffiness. It helps loosen thick mucus, making it easier to cough out. It also shrinks the blood vessels and provides rapid relief that lasts for several hours. These actions make breathing easier.

Actifed Plus Suspension is safe and effective. It usually starts to work within a few minutes, and the effects can last up to several hours. Take it as prescribed by your doctor, and do not stop using it unless you are advised otherwise.

Side effects of Actifed Plus Suspension

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Actifed Plus

Nausea
Sleepiness
Allergic reaction
High blood pressure
Insomnia (difficulty in sleeping)
Palpitations

How to use Actifed Plus Suspension

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Actifed Plus Suspension may be taken with or without food.

How Actifed Plus Suspension works

Actifed Plus Suspension is a combination of three medicines: Paracetamol, Triprolidine and Phenylpropanolamine which relieve cold symptoms. Paracetamol is an analgesic (pain reliever) and antipyretic (fever reducer). It blocks the release of certain chemical messengers in the brain that cause pain and fever. Triprolidine is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing. Phenylpropanolamine is a decongestant which narrows the small blood vessels providing relief from congestion or stuffiness in the nose.

Quick tips

Actifed Plus Suspension is prescribed to get relief from symptoms of common cold.
Take exactly as directed by your doctor or on the label. Do not increase the dosage or take for longer than is recommended.
Call your doctor if your symptoms have not improved within seven days of treatment.
Inform your doctor if you are taking any other medications for cold.
Along with taking Actifed Plus Suspension do the following simple tips at home to get relief:
1. Steam inhalation.
2. Gargling with warm saltwater.
3. Apply vapor rubs on chest, back if needed. Take enough rest.
4. Take warm food and fluid only. Ensure adequate fluid intake.
5. Advise hygiene measures to reduce spread: frequent hand-washing, avoiding sharing towels, pillowcases, etc.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Actifed Plus Suspension

Pregnancy

CONSULT YOUR DOCTOR

The safety of Actifed Plus Suspension during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Actifed Plus Suspension during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Actifed Plus Suspension may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Actifed Plus Suspension should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
However, Actifed Plus Suspension contains paracetamol which is considered the safest painkiller for kidney disease patients.

Liver

CAUTION

Actifed Plus Suspension should be used with caution in patients with liver disease. Dose adjustment may be needed.
However, the use of Actifed Plus Suspension is not recommended in patients with severe liver disease and active liver disease.

Fact Box

Habit Forming

Therapeutic Class

RESPIRATORY

References

De Sutter AI, Eriksson L, van Driel ML. Oral antihistamine-decongestant-analgesic combinations for the common cold. Cochrane Database Syst Rev. 2022 Jan 21;1(1):CD004976. [Accessed 23 Jan. 2026]. Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Glaxo SmithKline Pharmaceuticals Ltd
Address: Dr. Annie Besant Road, Mumbai - 400 030

Vendor Details

Country of origin: India

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