Zonic-S 500mg/500mg Tablet

Cefoperazone (500mg)+ Sulbactam (500mg)

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Zonic-S 500mg/500mg Tablet is a combination medicine. It is prescribed to treat various types of bacterial infections. It fights against the microorganisms to prevent their growth and further spread of the infection.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 28 Jan 2026 | 12:03 AM (IST)

₹157 MRP ₹178.1312% off

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Cefrite SB 500mg/500mg Tablet

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Zonic-S 500mg/500mg Tablet

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Same composition

Cefrite SB 500mg/500mg Tablet

strip of 10 tablets

Cefoperazone (500mg) + Sulbactam (500mg)

by Micro Labs Ltd

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₹231

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General Information

Contains

Cefoperazone (500mg)+ Sulbactam (500mg)

Marketer

H & Care Incorp

The content is shown in English

Product introduction

Zonic-S 500mg/500mg Tablet is a prescription medicine. It is advised to take it as per the prescription. It can be taken with or without food, but it must be taken at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine.

Some common side effects of this medicine are nausea, vomiting, diarrhea, indigestion, etc. If any of the side effects get aggravated, you must consult your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.

Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Pregnant or breastfeeding women should also consult with their doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. You must take adequate rest for a faster recovery, also take a healthy diet and drink plenty of water. Your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.

Uses of Zonic-S Tablet

Treatment of Bacterial infections

Benefits of Zonic-S Tablet

Treatment of Bacterial infections
Zonic-S 500mg/500mg Tablet contains two different medicines, Cefoperazone and Sulbactum, that work together to kill the bacteria that cause infections. Cefoperazone works by stopping the growth of bacteria. Sulbactam reduces resistance and enhances the activity of Cefoperazone against bacteria.

Zonic-S 500mg/500mg Tablet can be used to treat many different bacterial infections such as ear, sinus, throat, lung, urinary tract, skin and soft tissues. This medicine usually makes you feel better within a few days, but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Zonic-S Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zonic-S

Decreased white blood cell count (neutrophils)
Decreased white blood cell count (lymphocytes)
Decreased hemoglobin
Decreased hematocrit level
Low blood platelets
Coagulation disorder
Increased white blood cell count (eosinophils)
Diarrhea
Nausea
Increased alanine aminotransferase
Increased aspartate aminotransferase
Increased alkaline phosphatase level in blood
Vomiting
Increased bilirubin in the blood

How to use Zonic-S Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zonic-S 500mg/500mg Tablet may be taken with or without food.

How Zonic-S Tablet works

Zonic-S 500mg/500mg Tablet is a combination of two medicines: Cefoperazone and Sulbactam. Cefoperazone is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Sulbactam is a beta-lactamase inhibitor which reduces resistance and enhances the activity of Cefoperazone against bacteria.

All substitutes for Zonic-S 500mg/500mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Cefrite SB 500mg/500mg Tablet

by Micro Labs Ltd

₹23.1/tablet

85% cheaper

Quick tips

You have been prescribed this combination medicine to treat bacterial infections even if they have developed resistance.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Diarrhea may occur as a side effect. Taking probiotics along with Zonic-S 500mg/500mg Tablet may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
Stop taking Zonic-S 500mg/500mg Tablet and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.

Safety advice

Alcohol

UNSAFE

Consumption of alcohol with Zonic-S 500mg/500mg Tablet may cause a disulfiram-like reaction, leading to symptoms such as flushing, increased heart rate, low blood pressure, nausea, lightheadedness, and severe headache.

Pregnancy

SAFE IF PRESCRIBED

Zonic-S 500mg/500mg Tablet is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.

Breast feeding

SAFE IF PRESCRIBED

Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.

Driving

CONSULT YOUR DOCTOR

It is not known whether Zonic-S 500mg/500mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Zonic-S 500mg/500mg Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Zonic-S 500mg/500mg Tablet in patients with liver disease.

Frequently asked questions

What is Zonic-S 500mg/500mg Tablet?

Zonic-S 500mg/500mg Tablet is a combination of two medicines: Cefoperazone and Sulbactam. Cefoperazone is an antibiotic which works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Sulbactam is a beta-lactamase inhibitor which reduces resistance and enhances the activity of Cefoperazone against bacteria.

How long does Zonic-S 500mg/500mg Tablet takes to work?

Usually, Zonic-S 500mg/500mg Tablet starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.

What if I don't get better after using Zonic-S 500mg/500mg Tablet?

Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.

Fact Box

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: H & Care Incorp
Address: SCF- 250, Ground Floor,Motor Market, ManimajraChandigarh - 160101, India.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Zonic-S 500mg/500mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Product introduction

Uses of Zonic-S Tablet

Benefits of Zonic-S Tablet

Side effects of Zonic-S Tablet

How to use Zonic-S Tablet

How Zonic-S Tablet works

All substitutes for Zonic-S 500mg/500mg Tablet

Cefrite SB 500mg/500mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Zonic-S 500mg/500mg Tablet?

How long does Zonic-S 500mg/500mg Tablet takes to work?

What if I don't get better after using Zonic-S 500mg/500mg Tablet?

Fact Box

Habit Forming

Therapeutic Class

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests