Xolair 150mg Injection is a monoclonal antibody. It is used in the treatment of moderate to severe asthma in both adults and children. It eases the symptoms of asthma such as wheezing, breathlessness, tightness in your chest, and coughing.
Xolair 150mg Injection is given as an injection under the supervision of a doctor. The first three dose of medicine is given by the doctor. Your doctor will explain to you the best way to inject the medicine so that you can inject your medicine at home. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you even if you feel better.
The most common side effects of this medicine include joint pain, pain (general), fatigue, dizziness, fracture, itching, dermatitis, upper abdominal pain, nasopharyngitis, headache, and ear pain. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Remember, it does not prevent you from a sudden attack, hence always carry your emergency inhaler with you.
Before taking this medicine if you have liver or kidney disease, or if you are pregnant or planning pregnancy. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. In general, alcohol is not recommended while on treatment with this medicine.
Xolair 150mg Injection is used to treat the symptoms of asthma such as tightness in your chest, wheezing, breathlessness and coughing. This means you can carry out your daily activities more easily and more confidently. It may take a few weeks for this medicine to show full effects. It is given as an injection by a doctor or nurse and should not be self-administered. Taking this medicine enables you to live your life more freely without worrying so much about things that set off your symptoms.
In Urticaria
Xolair 150mg Injection can be very helpful for people with urticaria, particularly Chronic Idiopathic Urticaria (long-lasting hives that don’t have a clear cause). It works by reducing itching, swelling, and flare-ups when usual medicines like antihistamines are not enough. Many patients notice better sleep, fewer symptoms, and an improved quality of life. Since it is given once every 3 to 4 weeks, it also offers convenience without the need for daily medication. Most people tolerate it well, with only mild side effects in some cases.
Side effects of Xolair Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Xolair
Fracture
Itching
Dermatitis
Upper abdominal pain
Nasopharyngitis (inflammation of the throat and nasal passages)
Ear pain
Joint pain
Pain
Fatigue
Dizziness
How to use Xolair Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Xolair Injection works
Xolair 150mg Injection is a monoclonal antibody that works by targeting and blocking immunoglobulin E (IgE), a key antibody involved in allergic reactions. In asthma, IgE triggers inflammation in the airways when exposed to allergens. Xolair 150mg Injection binding to IgE and preventing it from attaching to immune cells, reduces allergic inflammation and helps prevent asthma attacks.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Xolair 150mg Injection. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Xolair 150mg Injection is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.
Breast feeding
CAUTION
Xolair 150mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving
UNSAFE
Xolair 150mg Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Xolair 150mg Injection is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.
Liver
CONSULT YOUR DOCTOR
There is limited data available on the use of Xolair 150mg Injection in patients with liver disease.
What if you forget to take Xolair Injection?
If you miss a dose of Xolair 150mg Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Xolair 150mg Injection is used for the treatment of moderate to severe asthma.
Seek immediate medical help if you experience symptoms like wheezing, shortness of breath, cough, chest tightness, swelling of the throat or tongue, or trouble breathing.
Inform your doctor immediately if your asthma remains uncontrolled or worsens after initiation of treatment.
Inform your doctor if you have any other allergies (such as food allergies or seasonal allergies).
Let your doctor know if you are or planning to become pregnant or breastfeeding.
Fact Box
Chemical Class
Peptides
Habit Forming
No
Therapeutic Class
RESPIRATORY
Action Class
Anti IgE monoclonal antibodies
FAQs
What is Xolair 150mg Injection used for?
Xolair 150mg Injection is used to treat moderate to severe asthma and chronic spontaneous urticaria (hives). In some cases, doctors may also prescribe Xolair 150mg Injection to treat food allergies in patients who do not get enough relief from standard treatments.
Can Xolair 150mg Injection be used for sudden asthma attacks or severe allergic reactions?
No. Xolair 150mg Injection is not a rescue medicine. It does not treat sudden asthma attacks, status asthmaticus, or emergency allergic reactions like anaphylaxis. You will still need a rescue inhaler or other crucial medicines for emergencies.
Who should not receive Xolair 150mg Injection?
People should not receive Xolair 150mg Injection if they are allergic to omalizumab or any ingredient in the medicine. Severe allergic reactions can occur, even after long-term use.
Can Xolair 150mg Injection cause serious allergic reactions?
Yes. Xolair 150mg Injection may cause serious allergic reactions (anaphylaxis), which can be life-threatening. It can happen right after the first dose or even more than a year after starting treatment. Signs include swelling of the throat or tongue, trouble breathing, dizziness, or fainting. Emergency medical care is needed in these cases.
Does Xolair 150mg Injection increase cancer risk?
Some studies have reported malignancies (cancers) in patients treated with Xolair 150mg Injection, though the risk is not fully established. Your doctor will weigh the benefits against potential risks before starting treatment.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Boushey HA. Drugs Used in Asthma. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 350.
Barnes PJ. Pulmonary Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1054.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1019-20.
Omalizumab. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2003 [revised Jul. 2016]. [Accessed 1 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:
Omalizumab Injection. Prescribing Information. South San Francisco, CA; Genentech, Inc.; 2024. [Accessed 23 Sep 2025] (online) Available from:
Omalizumab. East South San Francisco, CA: Genentech, Inc.; 2024. [Accessed 04 Nov. 2025] (online). Available from:
Country of origin: Switzerland Expires on or after: July, 2026
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