Reperi Gel

Written By Dr. Lipika Khurana, PGDHHM, BDS

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 18 Feb 2026 | 05:14 PM (IST)

Reperi Gel is a topical treatment for diabetic neuropathic pain. Applied directly to the affected area, it provides targeted relief by calming overactive nerve signals. With minimal absorption into the bloodstream, Reperi Gel reduces pain effectively while lowering the risk of systemic side effects.

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General Information

Contains

Pregabalin (8% w/w)

Marketer

Zuventus Healthcare Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Proper adherence to Reperi Gel is essential for effective pain management. Apply a thin layer to the affected area, as directed by your doctor. Consistent use ensures targeted relief of diabetic neuropathic pain. Avoid discontinuing use abruptly to maintain treatment benefits. Always follow your doctor’s guidance for optimal use.

Reperi Gel is generally well tolerated and no common side effects have been reported. However, if you experience any unusual symptoms or allergies, consult your doctor for advice. Discontinue immediately and seek medical help if you experience swelling of the throat, hives, or difficulty breathing, as these may indicate serious allergic reactions.

Avoid using Reperi Gel if you have known allergies to it or its ingredients. Although systemic absorption of the gel is minimal, consult your doctor about any other medications you are taking to avoid potential interactions. Pregnant and breastfeeding women should consult their doctor before using this medicine to make sure it is safe for them and the developing baby.

Uses of Reperi Gel

Treatment of Neuropathic pain

Benefits of Reperi Gel

Treatment of Neuropathic pain
Reperi Gel provides relief from neuropathic pain by reducing nerve sensitivity and calming overactive pain signals. When applied to the affected area, it helps alleviate burning, tingling, and shooting pain, allowing patients to experience greater comfort. It provides localized relief, improves mobility, sleep quality, and overall well-being. This enables individuals to go about their daily activities with less discomfort.

Side effects of Reperi Gel

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Reperi

Peripheral edema
Sleepiness
Weight gain
Dryness in mouth
Blurred vision
Dizziness
No common side effects seen

How to use Reperi Gel

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.

How Reperi Gel works

Reperi Gel works by increasing the production of nitric oxide and endogenous opioid release. Reperi Gel increases nitric oxide production, which could then enhance endogenous opioid release to reduce neuropathic pain.

All substitutes for Reperi Gel

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Always apply a thin layer of the gel to clean, dry skin over the affected area. Avoid applying to broken skin or open wounds.
Report any unusual skin reactions, swelling, or worsening pain to your doctor promptly.
Keep Reperi Gel in a cool and dry place, away from direct sunlight. Do not freeze the product.

Safety advice

Alcohol

No interaction found/established

Pregnancy

CONSULT YOUR DOCTOR

Reperi Gel is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Reperi Gel may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

No interaction found/established

Kidney

No interaction found/established

Liver

No interaction found/established

Frequently asked questions

Can Reperi Gel be used for other types of pain?

Reperi Gel is specifically approved for diabetic neuropathic pain. Using it for other types of pain should only be done after consulting a doctor.

Can I use Reperi Gel with other topical medications?

Avoid applying other topical treatments on the same area without consulting your doctor to prevent interactions or reduce effectiveness.

Is Reperi Gel safe for children?

The safety and effectiveness of Reperi Gel in children have not been established. Use in pediatric patients should be under strict medical supervision.

What is Reperi Gel and what is it used for?

Reperi Gel belongs to the anticonvulsants class of medicines. It is used to treat seizures. It is also helpful in treating nerve pain (neuropathic pain) which could be due to diabetes, shingles, or injury. It is also used in fibromyalgia (a long-lasting condition that may cause pain, tiredness, muscle stiffness and tenderness as well as difficulty falling or staying asleep. In some cases, your doctor may prescribe this medicine for the treatment of anxiety.

Reperi Gel has varied roles. Does it work in the same way for each disease?

No, Reperi Gel works in different ways for different diseases. In epilepsy, it stops seizures by reducing the abnormal electrical activity in the brain. In chronic pain, it blocks pain messages travelling from brain to spine.

I have been prescribed Reperi Gel for pain due to shingles. When can I expect relief from pain?

It may take a few weeks to see full benefits while taking Reperi Gel. However, people have experienced relief from pain after a week of starting Reperi Gel.

How long do I need to take Reperi Gel?

Duration for the use of Reperi Gel depends on the condition for which you are taking this medicine. If you are taking it for epilepsy, and it is effectively helping you then, you may have to continue it for years. If you are taking it for neuropathic or fibromyalgia pain, it is likely that once your symptoms improve you will have to continue taking it for several months. This will ensure that the problem does not come back. It is advised not to stop taking this medicine without consulting your doctor.

Is it necessary to continue taking Reperi Gel even if I feel fine?

Yes, you should not stop taking Reperi Gel even if you feel fine. If you are taking it for epilepsy and stop its consumption suddenly, you may have seizures that will not stop. Stopping it suddenly may result in withdrawal symptoms and you may experience anxiety, difficulty in sleeping, feeling sick, pain and sweating. These can be prevented if the dose of Reperi Gel is reduced gradually.

Is Reperi Gel addictive?

Addiction to Reperi Gel is more common in people who take it for unauthorized reasons. Taking Reperi Gel more than the recommended doses or taking it for long periods of time may also cause addiction. In addition to that, any person who has a history of drug abuse should never use Reperi Gel. In case you feel you are becoming physically dependent on Reperi Gel, inform your doctor immediately.

Can I take Diazepam and Reperi Gel together?

Yes, Reperi Gel and Diazepam can be used together. But, there might be a chance of increased side effects since both these medicines act on the brain to depress excessive activity.

Can the use of Reperi Gel cause weight gain?

Yes, Reperi Gel may cause weight gain because it increases your hunger. Regular physical exercise and a balanced diet with low-calorie food may help you keep your weight stable. Consult a dietician if you have any further concerns to keep your weight stable.

Fact Box

Chemical Class

Gamma amino acid derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Alpha-2 Delta Ligands- Antiepileptic Drugs (AEDs)

References

Stahl SM, editor. Pregabalin. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 557-60.
McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 599.
Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 410.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1149.
Pregabalin gel [Prescribing Information]. Bharuch, Gujarat: Torrent Pharmaceuticals Ltd.; 2024. [Accessed 11 Feb. 2025] (online) Available from:
Pregabalin gel [Prescribing Information]. Bharuch, Gujarat: Torrent Pharmaceuticals Ltd.; 2024. [Accessed 11 Feb. 2025] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Zuventus Healthcare Ltd
Address: Office No. 5119, 5th Floor, 'D' Wing, Oberoi Garden Estates, Chandivili, Andheri (E), Mumbai - 400 072.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Reperi Gel. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Reperi Gel

Save more with additional offers

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Reperi Gel

Benefits of Reperi Gel

Side effects of Reperi Gel

How to use Reperi Gel

How Reperi Gel works

All substitutes for Reperi Gel

pregaba Gel

pregabID Gel

preGAlin Gel

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

Can Reperi Gel be used for other types of pain?

Can I use Reperi Gel with other topical medications?

Is Reperi Gel safe for children?

What is Reperi Gel and what is it used for?

Reperi Gel has varied roles. Does it work in the same way for each disease?

I have been prescribed Reperi Gel for pain due to shingles. When can I expect relief from pain?

How long do I need to take Reperi Gel?

Is it necessary to continue taking Reperi Gel even if I feel fine?

Is Reperi Gel addictive?

Can I take Diazepam and Reperi Gel together?

Can the use of Reperi Gel cause weight gain?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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