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Pevesca Plus Capsule is used to treat neuropathic pain. It decreases the pain by controlling calcium channel activity and by decreasing the production of a substance that protects nerve fibers and rejuvenates damaged nerve cells.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 15 Dec 2025 | 03:14 PM (IST)
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General Information

Contains

Alpha Lipoic Acid (100mg)+ Folic Acid (1.5mg)+ Methylcobalamin (750mcg)+ Pregabalin (75mg)+ Vitamin B6 (Pyridoxine) (1.5mg)

Marketer

USV Private Limited

Storage

Store below 25°C
The content is shown in English
Pevesca Plus Capsule image
Pevesca Plus Capsule image
Pevesca Plus Capsule image
Pevesca Plus Capsule image
Pevesca Plus Capsule image
Pevesca Plus Capsule image

Product introduction

Pevesca Plus Capsule can be taken on empty stomach. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly without talking to the doctor.

Common side effects of this medicine include dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It may also cause nasopharyngitis, increased appetite, confusion, difficulty in sleeping, decreased libido, tremor, vision blurred, and vertigo. Inform your doctor if you develop any unusual changes in the mood or behavior, new or worsening depression, or suicidal thoughts. It is better to avoid alcohol while taking this medicine as it can enhance the dizziness effect of the drug.

Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Pevesca Plus Capsule

Benefits of Pevesca Plus Capsule

Neuropathic pain
Pevesca Plus Capsule is used to manage neuropathic pain by addressing nerve damage and reducing pain signals. It helps calm overactive nerves, while the vitamins and antioxidants support nerve repair and improve overall nerve health, providing relief from burning, tingling, or shooting pain.

Side effects of Pevesca Plus Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pevesca Plus
  • Dizziness
  • Uncoordinated body movements
  • Sleepiness
  • Tiredness
  • Nasopharyngitis (inflammation of the throat and nasal passages)
  • Increased appetite
  • Confusion
  • Insomnia (difficulty in sleeping)
  • Decreased libido
  • Tremors
  • Vertigo
  • Blurred vision

How to use Pevesca Plus Capsule

Take this medicine in the dose and duration as advised by your doctor. Pevesca Plus Capsule is to be taken on an empty stomach.

How Pevesca Plus Capsule works

Pevesca Plus Capsule is a combination of five medicines: Alpha Lipoic Acid, Folic Acid, Methylcobalamin, Pregabalin and Vitamin B6 (Pyridoxine). Alpha Lipoic Acid is a naturally occurring fatty acid which has a protective effect on the brain and nerve tissues. Folic Acid provides essential nutrients to the nerves. Methylcobalamin and Vitamin B6 (Pyridoxine) are forms of vitamin B which help in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Pregabalin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).

All substitutes for Pevesca Plus Capsule

For information purposes only. Consult a doctor before taking any medicine.

Pregadoc Plus Capsule

by Lupin Ltd
₹19.2/capsule
13% costlier
<h3 class=bodySemiBold>Pregadoc Plus Capsule</h3>

Pregastar Plus Capsule

by Lupin Ltd
₹22.93/capsule
35% costlier
<h3 class=bodySemiBold>Pregastar Plus Capsule</h3>

Quick tips

  • Pevesca Plus Capsule helps treat nerve pain caused by diabetes, shingles or an injury.
  • Its side effects are usually mild and go away by themselves.
  • It may cause sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking this medicine, as it may cause excessive sleepiness or drowsiness.
  • Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
  • Do not stop taking the medication suddenly without talking to your doctor.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Pevesca Plus Capsule.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Pevesca Plus Capsule during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Pevesca Plus Capsule may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Pevesca Plus Capsule may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

SAFE IF PRESCRIBED
Pevesca Plus Capsule is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.
Liver

Liver

SAFE IF PRESCRIBED
Pevesca Plus Capsule is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Frequently asked questions

Pevesca Plus Capsule is a combination of five medicines: Pregabalin, Methylcobalamin, Folic acid, Alpha lipoic acid, and Vitamin B6. This medicine is useful in the treatment of nerve pain (neuropathic pain). This medicine calms the damaged or overactive nerves by acting on the brain, thereby decreasing the pain sensation. It also helps in the regeneration of damaged nerves in the body.
No, you should not stop taking Pevesca Plus Capsule even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking Pevesca Plus Capsule, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain and sweating. You may need to gradually taper the use of Pevesca Plus Capsule before you stop the medication completely.
Pevesca Plus Capsule can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight. However, preventing weight gain is easier than losing the increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). Do not eat food items that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits and sweets. If you feel hungry between meals, avoid eating junk food and eat fruits, vegetables and low-calorie foods. Regular exercise will help prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.
Yes, Pevesca Plus Capsule may make you feel drowsy or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities until you know how the medicine affects you. Inform your doctor if you experience such episodes while you are taking this medicine.
Serious side effects because of Pevesca Plus Capsule are uncommon and rare. However, it may cause serious side effects like an allergic reaction, suicidal thoughts or swelling of limbs (hands, legs or feet). Stop taking Pevesca Plus Capsule and contact your health care provider if you have any signs of these serious side effects. Signs of allergic reaction include swelling of your face, mouth, lips, gums, tongue and neck, trouble in breathing, skin rash, hives (raised bumps) or blisters. Pay attention to sudden changes in mood, behaviors, thoughts, or feelings as these may be a symptom of suicidal thoughts.
An initial benefit with Pevesca Plus Capsule may be seen after 2 weeks of treatment. However, it may take around 2-3 months to see the full benefit. It may take longer in some patients.
If you forget to take the scheduled dose of Pevesca Plus Capsule and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effects. If you are not sure what to do, consult your doctor about how to manage a situation like this.
In a situation like this, contact your doctor immediately or seek emergency help at the nearest hospital. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Symptoms of an overdose may include drowsiness, weakness, unsteadiness while walking, having double visions, slurred speech or diarrhea, confusion, blurred vision, dizziness, body temperature changes (low and high), difficulty in breathing and increased heartbeat.
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms, that are not relieved by the recommended doses, please consult your doctor for re-evaluation.
No, do not drink alcohol while you are taking Pevesca Plus Capsule. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Pevesca Plus Capsule.
You may need to see your doctor regularly if you have started to take Pevesca Plus Capsule. However, consult your doctor if the recommended dosage does not improve your symptoms or you continue experiencing some unwanted side effect that affect your routine activities.
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Fact Box

Habit Forming

No

Therapeutic Class

NEURO CNS

References

  1. MedlinePlus. Vitamin B12. [Accessed 22 Apr. 2019] (online) Available from:
  2. Pregabalin. Vega Baja, Puerto Rico: Pfizer Pharmaceuticals LLC; 2009. [Accessed 22 Apr. 2019] (online) Available from:
  3. Pregabalin, Methylcobalamin, Alpha Lipoic Acid, Pyridoxine Hydrochloride and Folic Acid [Patient Information Sheet]. Solan, HP: Innova Captab Ltd.; 2021. [Accessed 14 Aug. 2024] (online) Available from:
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User feedback

Once A Day
100%
Neuropathic pain
75%
Others
16%
Nutritional deficiencies
9%
Average
36%
Excellent
33%
Poor
31%
Sleepiness
40%
No Side Effect
40%
Dizziness
20%
With food
70%
With or without food
20%
Empty stomach
10%
Average
48%
Expensive
41%
Not Expensive
11%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: USV Private Limited
Address: Arvind Vithal Gandhi Chowk, BSD Marg, Station Road, Govandi East, Mumbai - 400 088. , India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Pevesca Plus Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's â„ž and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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