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18 Feb 2020 | 05:25 PM (IST)
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Overview

Introduction

Pregadoc Plus Capsule is used to treat neuropathic pain. It decreases the pain by controlling calcium channel activity and by decreasing the production of a substance that protects nerve fibers and rejuvenates damaged nerve cells.

Pregadoc Plus Capsule can be taken on empty stomach. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly without talking to the doctor.

Some common side effects of this medicine dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to inform your doctor if you develop any unusual changes in the mood or behavior, new or worsening depression, or suicidal thoughts. It is better to avoid alcohol while taking this medicine as it can enhance the dizziness effect of the drug.

Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Pregadoc Plus Capsule

Side effects of Pregadoc Plus Capsule

Common
  • Dizziness
  • Sleepiness
  • Tiredness
  • Uncoordinated body movements

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Dizziness
    This is usually short-lived and should go away within a few days. If this happens, stop what you are doing and sit or lie down until you feel better. Lying still in a dark, quiet room may help reduce the spinning feeling. Sleep with your head slightly raised on two or more pillows. Get up slowly from a lying or sitting position. Get plenty of rest and try to relax as being anxious can make it worse. Try taking this medicine at bedtime to reduce the symptoms. Drinking plenty of water and ginger tea may also help. Avoid alcohol, caffeine and smoking as it will make you feel worse. Avoid driving or using tools or machinery until you feel better.
  • Coping with Sleepiness
    If the medicine is making you drowsy during the day, stop what you are doing and sit or lie down until you feel better. You can also consider taking a nap. Physical exercises such as walking may be helpful. Do not drink alcohol, as it will make you feel more tired. Avoid driving or operating heavy equipment when you are feeling drowsy. This problem usually goes away as your body gets used to the medicine. However, if it does not, ask your doctor if you can take your medicine at bedtime or whether the dose can be reduced.
  • Coping with Tiredness
    Make sure you rest and drink plenty of fluids. Eat a well-balanced diet to keep your energy levels up. Do not drink too much alcohol. Do not drive or use tools or machinery until you feel better. Other things that can help include doing some gentle exercise every day, prioritizing and pacing your activities and having a short nap if you need to. If you are still having problems after a week, speak to your doctor, as they may want to change you to a different type of medicine.

How to use Pregadoc Plus Capsule

Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Pregadoc Plus Capsule is to be taken empty stomach.

How Pregadoc Plus Capsule works

Pregadoc Plus Capsule is a combination of five medicines: Alpha Lipoic Acid, Folic Acid, Methylcobalamin/Mecobalamin, Pregabalin and Vitamin B6 (Pyridoxine). Alpha Lipoic Acid is a naturally occurring fatty acid which has a protective effect on the brain and nerve tissues. Folic Acid provides essential nutrients to the nerves. Methylcobalamin/Mecobalamin and Vitamin B6 (Pyridoxine) are forms of vitamin B which help in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Pregabalin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).

Safety Advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Pregadoc Plus Capsule. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Pregadoc Plus Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Pregadoc Plus Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Pregadoc Plus Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Pregadoc Plus Capsule is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Pregadoc Plus Capsule may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Pregadoc Plus Capsule is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pregadoc Plus Capsule may not be needed in these patients. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Pregadoc Plus Capsule
₹14.15/Capsule
₹12.32/Capsule
save 13%
₹15.35/Capsule
9% costlier
Pregabid Forte Capsule
Intas Pharmaceuticals Ltd
₹15.9/Capsule
12% costlier
₹16.88/Capsule
19% costlier
Trinerve Forte Capsule
Alkem Laboratories Ltd
₹19.25/Capsule
36% costlier

Quick Tips

  • Pregadoc Plus Capsule helps treat nerve pain caused by diabetes, shingles or an injury.
  • Its side effects are usually mild and go away by themselves.
  • It may cause sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking this medicine, as it may cause excessive sleepiness or drowsiness.
  • Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
  • Do not stop taking the medication suddenly without talking to your doctor.

Patient Concerns

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Dear sir I have been suffering from pain in my left leg since 4years, due to brain stroke affected 4 years ago. There are no proper sensations in my left leg, feeling numbness and also burning sensation, I have been treated but my pain in the leg is not cured, can you please help me with this
Dr. Vikas Sharma
Neurology
tab pregadoc 75 mg hs
Reserve plus capsule required of any laboratory
Dr. Vikas Sharma
Neurology
did not unbderstand your query
arrow
Do you have any questions related to Pregadoc Plus Capsule ?

FAQs

Q. What is Pregadoc Plus?

Pregadoc Plus is a combination of five medicines: Pregabalin, Methylcobalamin, Folic acid, Alpha lipoic acid, and Vitamin B6. This medicine is useful in the treatment of nerve pain (neuropathic pain). This medicine calms the damaged or overactive nerves by acting on the brain, thereby decreasing the pain sensation. It also helps in the regeneration of damaged nerves in the body.

Q. Can I stop taking Pregadoc Plus when my pain is relieved?

No, you should not stop taking Pregadoc Plus even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking Pregadoc Plus, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain and sweating. You may need to gradually taper the use of Pregadoc Plus before you stop the medication completely.

Q. How to manage weight gain associated with the use of Pregadoc Plus?

Pregadoc Plus can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight. However, preventing weight gain is easier than losing the increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). Do not eat food items that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits and sweets. If you feel hungry between meals, avoid eating junk food and eat fruits, vegetables and low-calorie foods. Regular exercise will help prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.

Q. Can the use of Pregadoc Plus cause sleepiness or drowsiness?

Yes, Pregadoc Plus may make you feel drowsy or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities until you know how the medicine affects you. Inform your doctor if you experience such episodes while you are taking this medicine.

Q. Are there any serious side effects associated with the use of Pregadoc Plus?

Serious side effects because of Pregadoc Plus are uncommon and rare. However, it may cause serious side effects like an allergic reaction, suicidal thoughts or swelling of limbs (hands, legs or feet). Stop taking Pregadoc Plus and contact your health care provider if you have any signs of these serious side effects. Signs of allergic reaction include swelling of your face, mouth, lips, gums, tongue and neck, trouble in breathing, skin rash, hives (raised bumps) or blisters. Pay attention to sudden changes in mood, behaviors, thoughts, or feelings as these may be a symptom of suicidal thoughts.

Q. How long will Pregadoc Plus take to act?

An initial benefit with Pregadoc Plus may be seen after 2 weeks of treatment. However, it may take around 2-3 months to see the full benefit. It may take longer in some patients.

Q. What if I forget to take Pregadoc Plus?

If you forget to take the scheduled dose of Pregadoc Plus and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effects. If you are not sure what to do, consult your doctor about how to manage a situation like this.

Q. What if I take too much of this drug by mistake?

In a situation like this, contact your doctor immediately or seek emergency help at the nearest hospital. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Symptoms of an overdose may include drowsiness, weakness, unsteadiness while walking, having double visions, slurred speech or diarrhea, confusion, blurred vision, dizziness, body temperature changes (low and high), difficulty in breathing and increased heartbeat.

Q. Will a higher than the recommended dose of Pregadoc Plus be more effective?

No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms, that are not relieved by the recommended doses, please consult your doctor for re-evaluation.

Q. Can I drink alcohol while taking Pregadoc Plus?

No, do not drink alcohol while you are taking Pregadoc Plus. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Pregadoc Plus.

Q. How often should I see the doctor?

You may need to see your doctor regularly if you have started to take Pregadoc Plus. However, consult your doctor if the recommended dosage does not improve your symptoms or you continue experiencing some unwanted side effect that affect your routine activities.

Q. What are the instructions for the storage and disposal of Pregadoc Plus?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Drugs.com. Alpha Lipolic Acid. [Accessed 22 Apr. 2019] (online) Available from:External Link
  2. Drugs.com. Folic acid. [Accessed 22 Apr. 2019] (online) Available from:External Link
  3. MedlinePlus. Vitamin B12. [Accessed 22 Apr. 2019] (online) Available from:External Link
  4. Pregabalin. Vega Baja, Puerto Rico: Pfizer Pharmaceuticals LLC; 2009. [Accessed 22 Apr. 2019] (online) Available from:External Link
  5. Mayo Clinic. Vitamin B-6. [Accessed 22 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
A licensed vendor partner from your nearest location will deliver Pregadoc Plus Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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