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Lupinem 500mg Injection

Imipenem (500mg)+ Cilastatin (500mg)

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Lupinem 500mg Injection is a combination of antibiotic medicines. It is prescribed to treat various types of severe bacterial infections. It fights against the infection-causing microorganisms to prevent further infections.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 08 May 2026 | 05:15 PM (IST)

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General Information

Contains

Imipenem (500mg)+ Cilastatin (500mg)

Marketer

Lupin Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

Lupinem 500mg Injection should only be administered under the supervision of a healthcare professional. Do not miss any scheduled appointments for taking this medicine. The course of the medicine should be completed even if you feel better.

The common side effects of this medicine are nausea, vomiting, diarrhea, rashes, etc. You may also experience injection site redness, swelling, and pain that goes away with time. If any of the side effects get aggravated, you must consult your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.

Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Pregnant or breastfeeding women should also consult with their doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy.

Uses of Lupinem Injection

Severe bacterial infections

Benefits of Lupinem Injection

Severe bacterial infections
Lupinem 500mg Injection works by killing bacteria which can cause serious infections. It is used to treat many different types of bacterial infections. It is given by a doctor or nurse into a vein and should not be self-administered. Lupinem 500mg Injection usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Lupinem Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Lupinem

Nausea
Vomiting
Diarrhea
Rash

How to use Lupinem Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Lupinem Injection works

Lupinem 500mg Injection is a combination of two medicines: Imipenem and Cilastatin. Imipenem is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria in the human body. Cilastatin is dehydropeptidase I inhibitor which blocks the activity of an enzyme (dehydropeptidase I) that causes breakdown of Imipenem. Hence, it helps Imipenem stay active in your body for a longer period of time.

All substitutes for Lupinem 500mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Lupinem 500mg Injection is used to treat severe bacterial infections, including those acquired in hospital and those involving many different types of bacteria.
It is given by a drip into a vein (intravenous infusion) over 20 to 60 minutes.
Tell you doctor if you are allergic to penicillin as this medicine should be avoided or used with caution in penicillin allergy.
Your doctor may monitor your liver and kidney function while you are having treatment with this medication.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Lupinem 500mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Lupinem 500mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

SAFE IF PRESCRIBED

Lupinem 500mg Injection may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving

UNSAFE

Lupinem 500mg Injection may cause side effects that could affect your ability to drive.
There are some side effects associated with this medicine (such as seeing, hearing, or feeling something that is not there) that may affect some patients' ability to drive.

Kidney

CAUTION

Lupinem 500mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Lupinem 500mg Injection in patients with liver disease.

Frequently asked questions

For how long is Lupinem 500mg Injection used?

Duration of treatment with Lupinem 500mg Injection depends on the severity of your infection, which will be decided by your doctor.

How long does Lupinem 500mg Injection take to work?

Usually, Lupinem 500mg Injection starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.

Fact Box

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Related lab tests

Complete Blood Count

References

User feedback

Patients taking Lupinem 500mg Injection

Twice A Day

56%

Thrice A Day

25%

Once A Week

Twice A Month

Once A Month

What are you using Lupinem Injection for?

Severe bacterial infections

92%

Others

How much was the improvement?

Average

48%

Excellent

43%

Poor

10%

What were the side-effects while using Lupinem 500mg Injection?

Vomiting

25%

Nausea

25%

No Side Effect

12%

Diarrhea

12%

Rash

12%

How do you take Lupinem Injection?

With or without food

80%

With food

20%

Please rate Lupinem 500mg Injection on price

Expensive

89%

Average

11%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Lupin Ltd
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Lupinem 500mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Lupinem 500mg Injection

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Lupinem Injection

Benefits of Lupinem Injection

Side effects of Lupinem Injection

How to use Lupinem Injection

How Lupinem Injection works

All substitutes for Lupinem 500mg Injection

I Nem 500mg/500mg Injection

Cilaxin 500 mg/500 mg Injection

CILAXTER 500 MG/500 MG INJECTION

Imicelum 500 mg/500 mg Injection

V Penum 500 mg/500 mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

For how long is Lupinem 500mg Injection used?

How long does Lupinem 500mg Injection take to work?

Fact Box

Habit Forming

Therapeutic Class

Related lab tests

Complete Blood Count

References

User feedback

Patients taking Lupinem 500mg Injection

What are you using Lupinem Injection for?

How much was the improvement?

What were the side-effects while using Lupinem 500mg Injection?

How do you take Lupinem Injection?

Please rate Lupinem 500mg Injection on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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