![](data:image/svg+xml,%3Csvg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 124px 36px"%3E%3C/svg%3E)
![](data:image/svg+xml,%3Csvg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 22px 22px"%3E%3C/svg%3E)
![](data:image/svg+xml,%3Csvg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 24px 24px"%3E%3C/svg%3E)
Imipenem + Cilastatin
INFORMATION ABOUT IMIPENEM + CILASTATIN
Imipenem + Cilastatin Uses
Imipenem+Cilastatin is used in the treatment of severe bacterial infections.
How Imipenem + Cilastatin works
Imipenem + Cilastatin is a combination of two medicines: Imipenem and Cilastatin. Imipenem is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria in the human body. Cilastatin is dehydropeptidase I inhibitor which blocks the activity of an enzyme (dehydropeptidase I) that causes breakdown of Imipenem . Hence, it helps Imipenem stay active in your body for a longer period of time.
Common side effects of Imipenem + Cilastatin
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common
Nausea, Vomiting, Diarrhea, Rash, Thrombophlebitis, Increased liver enzymes
CONTENT DETAILS
![](data:image/svg+xml,%3Csvg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 48 48"%3E%3C/svg%3E){kind=small}
Written By
Dr. Subita Alagh
BDS
Reviewed By
Dr. Rajeev Sharma
MBA, MBBS
Last updated
07 Apr 2021 | 05:27 AM (UTC)
![](data:image/svg+xml,%3Csvg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 90px 75px"%3E%3C/svg%3E)
We provide you with authentic, trustworthy and revelant information
Read our editorial policy
Medicine brands for Imipenem + Cilastatin
Expert advice for Imipenem + Cilastatin
- Imipenem + Cilastatin is used to treat severe bacterial infections, including those acquired in hospital and those involving many different types of bacteria.
- It is given by a drip into a vein (intravenous infusion) over 20 to 60 minutes.
- Tell you doctor if you are allergic to penicillin as this medicine should be avoided or used with caution in penicillin allergy.
- Your doctor may monitor your liver and kidney function while you are having treatment with this medication.
- Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
- Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
Frequently asked questions for Imipenem + Cilastatin
Duration of treatment with Imipenem+Cilastatin depends on the severity of your infection, which will be decided by your doctor.
Usually, Imipenem+Cilastatin starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.