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    Imipenem + Cilastatin

    Information about Imipenem + Cilastatin

    Imipenem + cilastatin uses

    Imipenem+Cilastatin is used in the treatment of severe bacterial infections.

    How imipenem + cilastatin works

    This is a combination of two medicines: Imipenem and Cilastatin. Imipenem is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria in the human body. Cilastatin is dehydropeptidase I inhibitor which blocks the activity of an enzyme (dehydropeptidase I) that causes breakdown of Imipenem. Hence, it helps Imipenem stay active in your body for a longer period of time.

    Common side effects of imipenem + cilastatin

    Nausea, Vomiting, Diarrhea, Rash
    Content Details
    Written By
    Dr. Sakshi Sharma
    Reviewed By
    Dr. Ashish Ranjan
    MD (Pharmacology), MBBS
    Last updated on:
    18 Feb 2020 | 05:24 PM (IST)
    Want to know more?
    Read Our Editorial Policy

    Available Medicine for Imipenem + Cilastatin

    • ₹1604 to ₹1950
      MSD Pharmaceuticals Pvt Ltd
      2 variant(s)
    • ₹726 to ₹2965
      Cipla Ltd
      3 variant(s)
    • ₹1883 to ₹2258
      Glenmark Pharmaceuticals Ltd
      2 variant(s)
    • ₹332 to ₹869
      Macleods Pharmaceuticals Pvt Ltd
      3 variant(s)
    • ₹729
      Lupin Ltd
      1 variant(s)
    • ₹1584
      Zydus Cadila
      1 variant(s)
    • ₹1395
      United Biotech Pvt Ltd
      1 variant(s)
    • ₹1166
      Micro Labs Ltd
      1 variant(s)
    • ₹511 to ₹2640
      Alkem Laboratories Ltd
      4 variant(s)
    • ₹1141 to ₹2326
      Emcure Pharmaceuticals Ltd
      2 variant(s)

    Expert advice for Imipenem + Cilastatin

    • Imipenem + Cilastatin is used to treat severe bacterial infections, including those acquired in hospital and those involving many different types of bacteria.
    • It is given by a drip into a vein (intravenous infusion) over 20 to 60 minutes.
    • Tell you doctor if you are allergic to penicillin as this medicine should be avoided or used with caution in penicillin allergy.
    • Your doctor may monitor your liver and kidney function while you are having treatment with this medication.
    • Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
    • Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

    Frequently asked questions for Imipenem + Cilastatin

    Imipenem + Cilastatin

    Q. For how long is Imipenem+Cilastatin used?

    Duration of treatment with Imipenem+Cilastatin depends on the severity of your infection, which will be decided by your doctor.

    Q. How long does Imipenem+Cilastatin take to work?

    Usually, Imipenem+Cilastatin starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.