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Lodoz 5 Tablet

Written By Dr. Lipika Khurana, PGDHHM, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 20 Jan 2026 | 02:25 AM (IST)
Lodoz 5 Tablet is a combination of two medicines used to treat hypertension (high blood pressure). It helps to control blood pressure when a single medication is not effective. It also helps to reduce the chances of any future heart attack and stroke.
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General Information

Contains

Bisoprolol (5mg)+ Hydrochlorothiazide (6.25mg)

Marketer

Merck Ltd

Storage

Store below 25°C
The content is shown in English
Lodoz 5 Tablet image
Lodoz 5 Tablet image
Lodoz 5 Tablet image
Lodoz 5 Tablet image
Lodoz 5 Tablet image
Lodoz 5 Tablet image
Lodoz 5 Tablet image

Product introduction

Lodoz 5 Tablet is taken with or without food, preferably in the morning to avoid frequent urination at night. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Maintaining an active lifestyle through regular exercise, managing your weight, and consuming a healthy diet will also help regulate your blood pressure. Follow your doctor’s advice while taking this medicine.


Common side effects of this medicine include nausea, vomiting, constipation, diarrhea, decreased blood pressure, and fatigue. Consult your doctor if any of these bother you, or get worse, or do not go away. Drink plenty of fluids while taking medication to help alleviate muscle weakness, dry mouth, and extreme thirst. Dizziness or headache may occur due to low blood pressure, but this gets better with time.


Before taking it, let your doctor know if you have any liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to inform your doctor about any other medications you are taking, especially those used to treat high blood pressure or heart conditions. You should have your blood pressure, kidney function, blood sugar level, and the levels of salts such as potassium or magnesium checked regularly to make sure that this medicine is working properly.

Uses of Lodoz Tablet

Benefits of Lodoz Tablet

Treatment of Hypertension (high blood pressure)
Lodoz 5 Tablet works by blocking the effects of some chemicals on your heart and blood vessels. It slows down your heart rate and helps the heart beat with less force. Additionally, it eliminates excess water from the body and increases urine output. This lowers your blood pressure and helps in reducing your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective, so keep taking it even if you feel well. Do not stop without talking to your doctor.

Side effects of Lodoz Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lodoz
  • Constipation
  • Fatigue
  • Headache
  • Altered blood lipid level
  • Decreased magnesium level in blood
  • Vomiting
  • Decreased blood pressure
  • Nausea
  • Diarrhea
  • Dizziness
  • Cold extremities
  • Slow heart rate
  • Increased blood uric acid

How to use Lodoz Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lodoz 5 Tablet may be taken with or without food.

How Lodoz Tablet works

Lodoz 5 Tablet is a combination of two blood-pressure-lowering medicines: Bisoprolol and Hydrochlorothiazide. Bisoprolol is a beta blocker. It works specifically on the heart to improve its efficiency in pumping blood throughout the body. Hydrochlorothiazide is a diuretic that lowers blood pressure by removing extra water from the body. Over time, it also relaxes blood vessels and improves blood flow.

All substitutes for Lodoz 5 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Corbis-H 5 Tablet

by Torrent Pharmaceuticals Ltd
₹11.67/tablet
20% cheaper
<h3 class=bodySemiBold>Corbis-H 5 Tablet</h3>

Bisobis H 5mg/6.25mg Tablet

by Corona Remedies Pvt Ltd
₹5.75/tablet
61% cheaper
<h3 class=bodySemiBold>Bisobis H 5mg/6.25mg Tablet</h3>

Bisoline-H Tablet

by Zeelab Pharmacy Pvt Ltd
₹1.38/tablet
91% cheaper
<h3 class=bodySemiBold>Bisoline-H Tablet</h3>

Quick tips

  • Lodoz 5 Tablet is a combination of two blood pressure-lowering medications used for the treatment of high blood pressure.
  • Do not stop taking Lodoz 5 Tablet suddenly, as it can cause your blood pressure to rise suddenly, thereby increasing the risk of heart attack and stroke.
  • It may cause dizziness. If this happens to you, get up slowly when rising from a sitting or lying position.
  • It can hide symptoms of low blood sugar if you're diabetic. Monitor your blood sugar levels regularly.
  • Lodoz 5 Tablet may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, muscle weakness, or very dry mouth.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Lodoz 5 Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Lodoz 5 Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

UNSAFE
Lodoz 5 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

UNSAFE
Lodoz 5 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

UNSAFE
Lodoz 5 Tablet is unsafe to use in patients with kidney disease and should be avoided.
Liver

Liver

UNSAFE
Lodoz 5 Tablet is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

Lodoz 5 Tablet is used to treat high blood pressure. It combines a beta-blocker (bisoprolol) that slows your heart rate with a water pill (hydrochlorothiazide) that helps remove extra salt and fluid from your body, thereby lowering blood pressure.
Serious side effects of Lodoz 5 Tablet may include allergic reactions, slow or irregular heartbeat, severe dizziness, difficulty breathing, swelling, or signs of skin cancer. If you notice any of these, contact a doctor immediately.
While taking Lodoz 5 Tablet, you should avoid alcohol, certain decongestants, and medicines that affect your heart or sugar levels without consulting your doctor. They may increase side effects or reduce the medicine’s effectiveness.
Although rare, Lodoz 5 Tablet may affect your eyes or vision. Some people may experience dry eyes, reduced tear flow, eye pain, or even vision loss due to fluid pressure in the eye. Contact your doctor if you notice any eye issues.
No, you should not stop taking Lodoz 5 Tablet suddenly, as it can cause your blood pressure to rise again quickly. Always follow your doctor’s instructions before stopping.

Fact Box

Habit Forming

No

Therapeutic Class

CARDIAC

Related lab tests

Kidney Function Test

References

  1. Bisoprolol fumarate and hydrochlorothiazide. Pomona, New York: Duramed Pharmaceuticals, Inc.; 2011. [Accessed 11 Apr. 2019] (online) Available from:
  2. Hydrochlorothiazide: Important Patient Information. Rochester, New York: University of Rochester Medical Center. [Accessed 06 Feb. 2019] (online) Available from:
  3. Bisoprolol Fumarate and Hydrochlorothiazide [Prescribing Information]. Burbank, CA: Bryant Ranch Prepack, Inc.; 2025. [Accessed 20 Jan. 2026] (online) Available from:
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User feedback

Twice A Day
86%
Once A Day
14%
Hypertension (high blood pressure)
93%
Others
3%
Angina (heart-related chest pain)
3%
Excellent
54%
Average
41%
Poor
6%
No Side Effect
80%
Nausea
7%
Fatigue
7%
Headache
7%
With food
71%
With or without food
18%
Empty stomach
12%
Expensive
56%
Average
44%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Merck Ltd
Address: L-2, J.R. Complex, Gate No. 4, Village Mandoli, Delhi-110 093, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Lodoz 5 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?
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Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose
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In accordance with the law
Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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