Methotrexate is an immunosuppressant. In rheumatoid arthritis, it works by decreasing the activity of the body's immune system. This decreases swelling, reduces pain and stiffness, and improves function. In psoriasis, it works by slowing down the rapid growth of skin cells.
Yes, Mtx 5mg Tablet can cause a sore mouth and mouth ulcers as side effects in some cases. Taking folic acid along with this medicine may help in reducing the ulcers. Ask your doctor if the dose can be reduced as dose reduction may further help in reducing the ulcers.
Q. Why do I have to take folic acid with Mtx 5mg Tablet?
Folic acid is required to make new cells in the body and Mtx 5mg Tablet decreases the folic acid levels in the body. Folic acid can help reduce some of the common side effects of Mtx 5mg Tablet such as mouth ulcers, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia and liver problems.
Q. Why do I need to take regular blood tests while taking Mtx 5mg Tablet?
Regular blood tests will help your doctor to check your response to Mtx 5mg Tablet and monitor you for side effects. You will need to regularly check your liver function and your blood counts (white blood cells, red blood cells and platelets). Your doctor may also order additional tests depending on the results.
Q. Can Mtx 5mg Tablet use make me more prone to infections?
Mtx 5mg Tablet may decrease the activity of your immune system. As a result, you may develop serious infections. There have been rare reports which suggest occurrence of serious lung infections with Mtx 5mg Tablet use. If you have an active infection, Mtx 5mg Tablet should be used with extreme caution.
Q. Can Mtx 5mg Tablet affect fertility?
Yes, Mtx 5mg Tablet may affect fertility in both males and females. It may cause a decrease in sperm count in males and menstrual disturbances in females. No need to worry, these effects are reversible and disappear once the therapy is discontinued.
Q. What to do if I am planning to become pregnant and my husband is taking Mtx 5mg Tablet?
You should avoid pregnancy if your husband is taking Mtx 5mg Tablet. Also, it is advised that pregnancy should be further avoided for a minimum of 3 months after the therapy as it can lead to serious fetal abnormalities.
Information last updated by Dr. Varun Gupta, MD Pharmacology on 2nd Oct 2021. The medicine details are for information purpose only. Consult a doctor before taking any medicine.