ISTamet
Composition for ISTamet Products
ISTamet Products are primarily used for
Type 2 diabetes mellitusProducts for ISTamet
ISTamet 50mg/500mg Tablet
strip of 15 tablets
MRP₹176.25
ISTamet 50mg/1000mg Tablet
strip of 15 tablets
MRP₹195
ISTamet XR 500 Tablet
strip of 15 Tablet pr
MRP₹221.25
ISTamet XR Tablet
strip of 10 tablet er
MRP₹179
ISTamet 100mg/1000mg Tablet
strip of 14 tablets
MRP₹314.06
Not Available
Substitute brands for ISTamet
About ISTamet Products
Uses of ISTamet Products
Sitagliptin + Metformin is used in the treatment of type 2 diabetes mellitus. It is used in addition to diet and exercise to improve blood sugar control in adults with type 2 diabetes.
ISTamet Products side effects
Common
Side Effects of ISTamet are Decreased appetite, Vomiting, Upper respiratory tract infection, Hypoglycemia (low blood glucose level), Nausea, Diarrhea, Abdominal bloating.
How ISTamet Products work
Sitagliptin + Metformin is a combination of two medicines: sitagliptin and metformin. Sitagliptin help your pancreas produce more insulin, facilitate effective use of insulin by the body, and reduce excess sugar that your liver makes. Metformin is a biguanide which lowers glucose production in the liver, delays glucose absorption from intestines and increases the body's sensitivity to insulin. Together, they provide better control of blood sugar.
In Depth Information for ISTamet Products
- You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.
- Take it with food to lower your chance of having an upset stomach.
- Take it in addition to regular exercise and healthy diet to lower levels of blood sugar.
- Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines.
- Monitor your blood sugar level regularly while you are taking this medicine.
- Inform your doctor about your diabetes treatment if you are due to have surgery under a general anaesthetic.
- Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as ISTamet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
Patient Concerns about ISTamet Products
Frequently asked questions about ISTamet Products
Q. What is ISTamet 50mg/500mg Tablet?
ISTamet 50mg/500mg Tablet is a combination of two medicines: sitagliptin and metformin. This medicine is used in the treatment of type 2 diabetes mellitus. It improves blood glucose levels in adults when taken along with a proper diet and regular exercise. Metformin lowers glucose production in the liver and improves insulin sensitivity. Sitagliptin inhibits the enzyme DPP4 and increases insulin release from the pancreas. This combination is not indicated for patients below 18 years of age.
Q. What are the possible side effects of ISTamet 50mg/500mg Tablet?
The use of ISTamet 50mg/500mg Tablet is associated with common side effects like diarrhea, headache, and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to vitamin B12 deficiency.
Q. Are there any specific conditions in which ISTamet 50mg/500mg Tablet should not be taken?
The use of ISTamet 50mg/500mg Tablet should be avoided in patients with known allergies to any of the components or excipients of this medicine. The use of this medicine should be avoided in patients with severe kidney impairment, liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Q. Is it safe to take alcohol while I am taking ISTamet 50mg/500mg Tablet?
No, it is not safe to consume alcohol along with ISTamet 50mg/500mg Tablet, as it can increase the chances of lactic acidosis.
Q. Can the use of ISTamet 50mg/500mg Tablet lead to lactic acidosis?
Yes, the use of ISTamet 50mg/500mg Tablet can lead to lactic acidosis. It is a medical emergency caused by the increased levels of lactic acid in the blood. It is also known as MALA (metformin-associated lactic acidosis). It is a rare side effect associated with the use of metformin. Therefore, it is avoided in patients with underlying kidney disease, elderly patients, or those who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, a feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain, or a slow heart rate. If you have these symptoms, stop taking sitagliptin + metformin and immediately consult your doctor.
Q. Can the use of ISTamet 50mg/500mg Tablet lead to vitamin B12 deficiency?
Yes, using ISTamet 50mg/500mg Tablet can cause vitamin B12 deficiency in the long term. It interferes with the absorption of vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems, as a result of which the patient can feel a tingling sensation and numbness in hands and feet, weakness, urinary problems, a change in mental status, and difficulty maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of vitamin B12 from outside sources at least once every year.
Q. What are the instructions for storage and disposal of ISTamet 50mg/500mg Tablet?
Keep this medicine tightly closed in the container or pack it came in. Store it according to the instructions on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, or other people.