Vasculitis Panel near me in Pune

The PR3, also known as the Proteinase 3 (PR3) antibody test, measures the presence of antibodies directed against proteinase 3, which is an enzyme found in neutrophils (a type of white blood cell). The presence of these antibodies are often associated with autoimmune conditions, particularly granulomatosis with polyangiitis (GPA), a form of vasculitis.  Elevated PR3 antibody levels can indicate active disease and may help in monitoring both the progression of the condition and the response to treatment.

The MPO (Myeloperoxidase Anti-Neutrophil Cytoplasmic Antibodies) test detects autoantibodies against myeloperoxidase (MPO), an enzyme found in neutrophils (a type of white blood cell). These autoantibodies, called anti-MPO antibodies, are associated with autoimmune diseases like Vasculitis, especially Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA). A positive result is commonly seen in these types of vasculitis, aiding in diagnosis and treatment planning. The test is especially useful for differentiating GPA and MPA from other vasculitis forms, providing valuable insight for effective management.

The GBM, (Glomerular Basement Membrane) test detects antibodies against the glomerular basement membrane, associated with Goodpasture's Syndrome, an autoimmune disorder affecting the kidneys and lungs. A positive result indicates the presence of antibodies that damage kidney tissue, leading to glomerulonephritis or pulmonary hemorrhages. The test is crucial for diagnosing Goodpasture’s Syndrome, distinguishing it from other kidney conditions, and guiding treatment to prevent further organ damage.