SSB - LA (Soluble Substance B) - IgG antibody

Also referred as

Anti-La

Autoimmune

SS-B (La)

For men & women

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₹1579

~~₹1600~~

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The SSB - LA (Soluble Substance B) - IgG antibody test detects SS-B (La) antibodies in the blood. These antibodies are key markers for autoimmune diseases such as Sjögren’s syndrome (SS) and systemic lupus erythematosus (SLE). This test supports the diagnosis and differentiation between different autoimmune disorders.

Samples required

Blood

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Preparations

No special preparation is required.

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Tata 1mg certified phlebotomists

Understanding SSB - LA (Soluble Substance B) - IgG antibody

The SSB - LA (Soluble Substance B) - IgG antibody test is a blood test used to identify autoantibodies against the SS-B (La) antigen, a protein found inside cells. SS-B antibodies are commonly associated with Sjögren’s syndrome and are also seen in systemic lupus erythematosus (SLE) and other connective tissue diseases.

Doctors recommend the SSB - LA (Soluble Substance B) - IgG antibody test when symptoms like chronic dry eyes, dry mouth, joint pain, fatigue, or skin rashes suggest an autoimmune condition. Anti SS-B antibodies are often tested along with anti-SSA antibodies, as both can appear together in similar disorders.

The SSB - LA (Soluble Substance B) - IgG antibody test is particularly important for supporting a suspected diagnosis of Sjögren’s syndrome or lupus, differentiating between overlapping autoimmune conditions, and assessing risks in pregnant women with autoimmune diseases, as certain antibodies can affect the newborn. Early detection plays a key role in planning the right treatment and monitoring disease progression effectively.

No special preparation is required for the SSB - LA (Soluble Substance B) - IgG antibody test. Inform the doctor about all the medications and supplements currently being taken, as some of them may affect the test results. Your doctor may advise changes if needed before the test.

Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Do not self-medicate and always consult a doctor to understand the test results correctly.

Please note: This is an outsourced test. The sample is collected by TATA 1MG and processed at a NABL accredited partnered lab.

What does SSB - LA (Soluble Substance B) - IgG antibody measure?

The SSB - LA (Soluble Substance B) - IgG antibody is a blood test that detects IgG autoantibodies that react against the SS-B (La) antigen. A positive result indicates an autoimmune response and helps support the diagnosis of disorders such as lupus or Sjögren’s syndrome.

Test Information is reviewed by: Dr. Swati Gupta (Anand), MBBS, MD Lab Medicine and written by Dr. Lipika Khurana, PGDHHM, BDS . The test details are for information purpose only. Consult a doctor before taking any test. Last updated on: 22nd Aug 2026

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SSB - LA (Soluble Substance B) - IgG antibody test price for other cities

Price in	New Delhi	Rs. 1579
Price in	Mumbai	Rs. 1689
Price in	Bangalore	Rs. 1669
Price in	Kolkata	Rs. 1439
Price in	Pune	Rs. 1789

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FAQs related to SSB - LA (Soluble Substance B) - IgG antibody

What is the SSB - LA (Soluble Substance B) - IgG antibody test?

The SSB - LA (Soluble Substance B) - IgG antibody test detects the presence of SS-B (La) antibodies in the blood. These antibodies are important markers for systemic lupus erythematosus (SLE) and Sjögren's syndrome (SS).

What are anti SS-B antibodies?

They are autoantibodies that target parts of your body’s own cells, often seen in autoimmune diseases like lupus or Sjögren’s syndrome.

Do I need to fast for the SSB - LA (Soluble Substance B) - IgG antibody test?

No, fasting is not required for this test.

How is the test performed?

A blood sample is collected from a vein and analyzed using ELISA technology in the laboratory.

Is there any risk associated with the SSB - LA (Soluble Substance B) - IgG antibody test?

No, the SSB - LA (Soluble Substance B) - IgG antibody test is generally safe with minimal risks. You may feel slight discomfort, bruising, or swelling at the blood draw site, which resolves on its own and is not bothersome.

Who should get tested?

The SSB - LA (Soluble Substance B) - IgG antibody test is useful for individuals showing signs of autoimmune disorders such as dry eyes/mouth, skin sensitivity, or joint problems.

What do positive results mean?

A positive result may indicate conditions like SLE, Sjögren’s syndrome, or neonatal lupus in newborns of affected mothers, but does not confirm the diagnosis on its own.

Can the test be used during pregnancy?

Yes, it is often used in pregnant women with lupus or Sjögren’s to assess the risk of complications like congenital heart block in the baby.

Are Anti SS-A and Anti SS-B antibodies the same?

No, they are different antibodies. Both are often tested together as they are associated with overlapping conditions.

What other tests might be done along with the SSB - LA (Soluble Substance B) - IgG antibody test?

Doctors may also order Anti-SS-A, ANA, Anti-dsDNA, Anti-SS-B, ESR, or CRP tests to support diagnosis and monitor inflammation.

Is the test result always conclusive?

No. While it supports diagnosis, results should be interpreted along with symptoms and other test findings.

How does Tata 1mg ensure accurate lab test results?

Tata 1mg ensures accurate lab test results through certified laboratories that use advanced technology and adhere to stringent quality control measures. This commitment to high standards guarantees reliable results.

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