SSA - RO (Soluble Substance A)- IgG antibody

Also referred as

Anti-Ro

Autoimmune

SS-A (Ro)

SS-A Antibody Test

Anti-Ro Antibody Test

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~~₹1600~~

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The SSA - RO (Soluble Substance A)- IgG antibody test detects the presence of SSA (Ro) antibodies in the blood. These autoimmune antibodies, which are important markers for systemic lupus erythematosus (SLE) and Sjögren's syndrome (SS), help support the diagnosis of these conditions.

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Understanding SSA - RO (Soluble Substance A)- IgG antibody

The SSA - RO (Soluble Substance A)- IgG antibody test is used to detect autoantibodies directed against SS-A (Ro) antigens, which are proteins found inside cells that the immune system may mistakenly target. These antibodies are commonly seen in autoimmune diseases, especially Sjögren’s syndrome (SS) and systemic lupus erythematosus (SLE). The presence of these antibodies may also be associated with other connective tissue disorders.

The SSA - RO (Soluble Substance A)- IgG antibody test is often recommended when symptoms like dry eyes, dry mouth, joint pain, fatigue, or skin rashes are present. It is also useful during pregnancy to assess risk in women with autoimmune diseases, as SS-A antibodies may affect the fetus, causing issues like congenital heart block.

Detecting Anti-SS-A antibodies helps doctors support the diagnosis, distinguish between overlapping autoimmune conditions, and plan appropriate treatment.

Overnight fasting for 8–12 hours is preferred for the SSA - RO (Soluble Substance A)- IgG antibody test but not mandatory. Follow your doctor’s instructions regarding fasting. It is also preferable to provide clinical history. Inform the doctor about all the medications and supplements being taken, as some of them may affect the test results. Your doctor may advise changes if needed before the test.

Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Do not self-medicate and always consult a doctor to understand the test results correctly.

Please note: This is an outsourced test. The sample is collected by TATA 1MG and processed at a NABL accredited partnered lab.

What does SSA - RO (Soluble Substance A)- IgG antibody measure?

The SSA - RO (Soluble Substance A)- IgG antibody is a blood test that detects IgG autoantibodies that react against SS-A (Ro) antigens. A positive result suggests an autoimmune response and helps confirm disorders such as lupus or Sjögren’s syndrome.

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Test Information is reviewed by: Dr. Swati Gupta (Anand), MBBS, MD Lab Medicine and written by Dr. Lipika Khurana, PGDHHM, BDS . The test details are for information purpose only. Consult a doctor before taking any test. Last updated on: 24th Sep 2026

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SSA - RO (Soluble Substance A)- IgG antibody test price for other cities

Price in	New Delhi	Rs. 1579
Price in	Mumbai	Rs. 1579
Price in	Bangalore	Rs. 1579
Price in	Kolkata	Rs. 1439
Price in	Hyderabad	Rs. 1560

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FAQs related to SSA - RO (Soluble Substance A)- IgG antibody

What is the SSA - RO (Soluble Substance A)- IgG antibody test?

The SSA - RO (Soluble Substance A)- IgG antibody test detects the presence of SSA (Ro) antibodies in the blood. These antibodies are important markers for systemic lupus erythematosus (SLE) and Sjögren's syndrome (SS).

What are Anti SS-A antibodies?

They are autoantibodies that target parts of your body’s own cells, often seen in autoimmune diseases like lupus or Sjögren’s syndrome.

Do I need to fast for the SSA - RO (Soluble Substance A)- IgG antibody test?

Overnight fasting is preferred for this test but not mandatory. It is advised to follow your doctor’s instructions on this.

How is the test performed?

A blood sample is collected from a vein and analyzed using ELISA technology, a lab method to detect antibodies, in the laboratory.

Is there any risk associated with the SSA - RO (Soluble Substance A)- IgG antibody test?

No, the SSA - RO (Soluble Substance A)- IgG antibody test is generally safe with minimal risks. You may feel slight discomfort, bruising, or swelling at the blood draw site, which resolves on its own and is not bothersome.

Who should get tested with SSA - RO (Soluble Substance A)- IgG antibody?

The SSA - RO (Soluble Substance A)- IgG antibody test is useful for individuals showing signs of autoimmune disorders such as dry eyes/mouth, skin sensitivity, or joint problems.

What do positive results mean?

A positive result may indicate conditions like SLE, Sjögren’s syndrome, or neonatal lupus in newborns of affected mothers.

Can the test be used during pregnancy?

Yes, it is often used in pregnant women with lupus or Sjögren’s to assess the risk of complications like congenital heart block in the baby. Your doctor will guide the next steps for safety.

Are SS-A and SS-B antibodies the same?

No, they are different antibodies. Both are often tested together as they are associated with overlapping conditions.

What other tests might be done along with the SSA - RO (Soluble Substance A)- IgG antibody test?

Doctors may also order ANA, Anti-dsDNA, Anti-SS-B, ESR, or CRP tests to support diagnosis and monitor inflammation.

Is the test result always conclusive?

No. While it supports diagnosis, results should be interpreted along with symptoms and other test findings.

How does Tata 1mg ensure accurate lab test results?

Tata 1mg ensures accurate lab test results through certified laboratories that use advanced technology and adhere to stringent quality control measures. This commitment to high standards guarantees reliable results.

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