Rubella Virus Avidity

Rubella, also called German measles or 3-day measles, is a contagious viral infection caused by the rubella virus. It usually causes mild symptoms such as fever, skin rash, headache, stuffy and runny nose, red itchy eyes, and general discomfort. However, it may pose a significant risk to unborn babies whose mothers become infected during pregnancy, and serious birth defects called congenital rubella syndrome (CRS) could develop, especially during the first trimester. Miscarriage and stillbirth are possible consequences for those who are pregnant. Vaccination is the best way to prevent these complications.

The Rubella Virus Avidity test plays an important role in assessing the timing of rubella infection. While a standard rubella IgG test shows whether a person has antibodies against the virus, the avidity test measures how strongly those antibodies bind to the virus. Low-avidity IgG antibodies suggest a recent or primary infection, whereas high-avidity IgG antibodies indicate past infection or immunity from vaccination. This distinction is especially crucial in pregnancy, where knowing whether the infection is recent or old guides medical decisions.

Doctors may recommend this test if a woman tests positive for rubella IgM antibodies during pregnancy, when it is unclear whether the infection is new or old. It may also be advised if routine prenatal screening shows equivocal results or if there is a suspected exposure to rubella. In such cases, the avidity test provides clarity, helping doctors decide the best course of care

No special preparation is needed before taking this test. However, it is important to inform the doctor about any medications being taken or any recent infections, as these can affect results. During the test, details such as the specimen type, collection site, clinical history, and the clinician’s contact number are also required for accurate reporting and notification.

Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Do not self-medicate and always consult a doctor to understand the test results correctly.

Please note: This is an outsourced test. The sample for this test is collected by TATA 1MG and processed at a NABL accredited partnered lab.