Rheumatoid Arthritis & Autoimmune Screening Profile

The SS-B/La measures the presence of antibodies against the SS-B antigen in the blood. These antibodies are often associated with autoimmune disorders, particularly Sjorgen's syndrome. This test is used alongside SS-A (Ro) antibody test to help in the diagnosis of Sjogren's syndrome and other autoimmune diseases like Systemic lupus erythematosus (SLE). Detecting SS-B antibodies helps doctors assess autoimmune activity, confirm diagnosis and differentiate between various autoimmune conditions. However, the presence of SS-B antibodies alone is not definitive, and results should be interpreted in conjunction with clinical symptoms and other laboratory findings.

The ds-DNA test detects the presence of antibodies specifically directed against the genetic material called double-stranded DNA (dsDNA) found in the nucleus of cells. These antibodies are often found in systemic lupus erythematosus (SLE), an autoimmune disease where the immune system mistakenly attacks its own DNA. A positive result means that these antibodies are present, suggesting active disease or flare-ups, especially in the kidneys. A negative result means the antibodies were not found, making SLE less likely but not ruling it out completely. This test helps doctors understand if the disease is active and monitor how well treatments are working.

The IgG (Anti IgM - RF- IgM Detection) test detects the presence of IgG antibodies that react with IgM antibodies, which are often associated with autoimmune diseases like rheumatoid arthritis. A positive test result means IgG anti-IgM antibodies are detected, suggesting the presence of an autoimmune condition such as rheumatoid arthritis. On the other hand, a negative test result means no IgG anti-IgM antibodies are found, indicating that an autoimmune disease like rheumatoid arthritis is less likely. This test helps doctors understand if the disease is active and monitor how well treatments are working.

The SS-A/Ro60 test detects antibodies against the Ro60 protein, which is part of the SS-A (Ro) antigen. These antibodies are commonly found in autoimmune conditions like systemic lupus erythematosus (SLE) and Sjögren's syndrome. A positive result for SS-A/Ro60 antibodies suggests an increased likelihood of these autoimmune diseases and may also indicate a higher risk of complications, such as neonatal lupus and congenital heart block in infants born to mothers with these antibodies.  However, a negative result does not completely rule out these autoimmune diseases. Additional tests may be needed to confirm a diagnosis or explore other possible autoimmune conditions.

The ACPA/CP4-2 test is a blood test used to detect the presence of anti-citrullinated protein antibodies (ACPA), which are commonly associated with autoimmune diseases like rheumatoid arthritis. These antibodies target proteins that have undergone a process called citrullination, which is often seen in individuals with rheumatoid arthritis. A positive test result means ACPA are detected, suggesting the presence of rheumatoid arthritis or an increased risk of developing it, while a negative result means these antibodies are not present, making the condition less likely. This test helps doctors understand if the disease is active and monitor how well treatments are working.

The ACPA/CP4-3 test is a blood test used to detect the presence of anti-citrullinated protein antibodies (ACPA), which are commonly associated with autoimmune diseases like rheumatoid arthritis. These antibodies target proteins that have been modified by a process called citrullination, which is often seen in individuals with rheumatoid arthritis. A positive test result means ACPA are detected, suggesting the presence of rheumatoid arthritis or an increased risk of developing it, while a negative result means these antibodies are not present, making the condition less likely. This test helps doctors understand if the disease is active and monitor how well treatments are working.

The RA33 test used to detect RA33 antibodies, which are autoantibodies that can be present in people with autoimmune diseases, particularly rheumatoid arthritis (RA). RA33 is a type of antibody that targets proteins in the cell's nucleus. It is often found in rheumatoid arthritis (RA) but can also be present in other autoimmune diseases like systemic lupus erythematosus (SLE). Positive result indicates the presence of RA33 antibodies, suggesting a higher likelihood of rheumatoid arthritis or another autoimmune condition. A negative result means these antibodies aren't detected, making RA less likely, although it doesn't completely rule out the disease and may require addition testings for an accurate diagnosis. This test helps doctors diagnose and monitor rheumatoid arthritis or other autoimmune diseases.

The ACPA/CP4-4 test used to detect anti-citrullinated protein antibodies (ACPA), which are linked to rheumatoid arthritis (RA). This test specifically looks for antibodies that target proteins modified by citrullination, a process often seen in people with RA. A positive result suggests the presence of RA or an increased risk of developing it. A negative result means these antibodies are not present, making RA less likely, but further testing may be needed to confirm the diagnosis. This test helps doctors diagnose rheumatoid arthritis and monitor how well treatments are working.

The SSA-A/Ro52 test detects antibodies against the Ro52 protein, which is a component of the SS-A (Ro) antigen. These antibodies are commonly associated with autoimmune diseases such as systemic lupus erythematosus (SLE), Sjögren's syndrome, and other connective tissue disorders. A positive result for SSA-A/Ro52 antibodies can help support the diagnosis of these conditions, especially in cases where other tests, like the SS-A/Ro60 test, may not be positive. Additionally, the presence of Ro52 antibodies may be linked to a higher risk of developing complications like neonatal lupus or congenital heart block in babies born to mothers with these antibodies. However, a negative result does not completely rule out these conditions,

The ACPA/CP4-1 test used to detect anti-citrullinated protein antibodies (ACPA), which are associated with rheumatoid arthritis (RA). This test specifically looks for antibodies that target citrullinated proteins, a process that is common in RA. A positive result indicates the presence of ACPA, suggesting the likelihood of rheumatoid arthritis or an increased risk of developing it. A negative result means these antibodies are not found, making RA less likely, but additional testing may be needed for confirmation. This test helps doctors in diagnosing rheumatoid arthritis and monitoring treatment effectiveness.

An Anti-Nuclear Antibody (ANA) by IFA - End Point Titer test checks for antinuclear antibodies (ANA) in your blood. These antibodies, different from typical ones that fight off invaders in the body, can attach to structures inside the body’s own cell nuclei. If ANAs are present in the blood, it may suggest that your immune system is overly sensitive, causing inflammation against your own tissues and possibly indicating autoimmune diseases.