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PR3 (c-ANCA)

PR3 (c-ANCA) near me in Indore

Also referred as
c-ANCA
SERIN PROTEINASE 3 ANTIBODIES
Proteinase 3
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Know more about this test

The PR3 (c-ANCA) test is a blood test that helps diagnose certain autoimmune diseases, such as granulomatosis with polyangiitis (GPA), previously called Wegener's granulomatosis, and other forms of vasculitis (inflammation of blood vessels). It helps measure the antibodies against a specific protein called proteinase 3 (PR3), which is found in neutrophils (a type of white blood cell) that help fight off infections. It facilitates the prompt detection of these diseases and helps prevent organ damage by enabling timely treatment. This test is widely available with Tata 1mg labs at an affordable price in Indore.

A doctor may advise a PR3 (c-ANCA) test when there are symptoms of autoimmune vasculitis. General symptoms may include fever, fatigue, headache, weight loss, aches and pains, etc. Other symptoms depend on the parts of the body affected.

No special preparation is required for the PR3 (c-ANCA) test. Inform a doctor about all the medications (e.g., immunosuppressants, steroids, etc.) and supplements (e.g., biotin, etc.) that are currently being taken, as some of them may affect the test results, potentially requiring dosage adjustments or temporary discontinuation before the test.

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Understanding PR3 (c-ANCA)

PR3 antibodies are formed when the immune system mistakenly attacks the PR3 enzyme, found inside neutrophils. These antibodies are also called c-ANCA (cytoplasmic antineutrophil cytoplasmic antibodies) due to their staining pattern (diffuse, granular appearance of cytoplasm) during lab tests.

The PR3 (c-ANCA) test helps diagnose autoimmune diseases such as GPA and other forms of vasculitis, monitor disease activity, guide treatment decisions, and rule out other conditions that can cause similar symptoms, such as infections or other autoimmune diseases.

A doctor may advise a PR3 (c-ANCA) test when there are symptoms of autoimmune vasculitis. General symptoms may include fever, fatigue, headache, weight loss, aches and pains, etc. Other symptoms depend on the parts of the body affected.

No special preparation is required for the PR3 (c-ANCA) test. Inform a doctor about all the medications (e.g., immunosuppressants, steroids, etc.) and supplements (e.g., biotin, etc.) that are currently being taken, as some of them may affect the test results, potentially requiring dosage adjustments or temporary discontinuation before the test.

Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Do not self-medicate, and always consult a doctor to understand the test results correctly.

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What does PR3 (c-ANCA) measure?

The PR3 (c-ANCA) is a blood test that measures the levels of autoantibodies targeting the proteinase 3 (PR3) enzyme (located inside neutrophils). These autoantibodies are associated with autoimmune vasculitis disorders, particularly granulomatosis with polyangiitis (GPA), and other forms of vasculitis, where the immune system mistakenly attacks small blood vessels. This test helps diagnose these diseases, track disease activity, evaluate treatment response, and predict flare-ups.

Active inflammation is usually suggested by high PR3-ANCA levels, whereas a decline in their levels can indicate the effectiveness of treatment. Results should, however, be interpreted in conjunction with clinical symptoms, as not all individuals with these diseases are positive, and false positive results may occur with other conditions such as infections.

FAQs related to PR3 (c-ANCA) in Indore

The PR3 (c-ANCA) test detects autoantibodies targeting the PR3 enzyme in neutrophils. It helps diagnose and monitor autoimmune vasculitis disorders, particularly granulomatosis with polyangiitis (GPA).
No special preparation is required for this test.
The test is done by taking a blood sample from a vein in your arm. The sample is then analyzed for the levels of PR3 (c-ANCA) in the lab.
No, the PR3 (c-ANCA) test is generally safe with minimal risks. You may feel slight discomfort, bruising, or swelling at the blood draw site, which resolves on its own and is not bothersome.
Yes. In Indore, you can schedule the PR3 (c-ANCA) test near you with Tata 1mg Labs. The test is easy to book, cost-effective, and available with a comprehensive report.
Yes, home sample collection for the PR3 (c-ANCA) test is readily available in Indore. Tata 1mg Labs allows you to choose a date and time that suits your schedule for sample collection.
If you want to schedule the PR3 (c-ANCA) test with Tata 1mg Labs in Indore, the procedure is fairly easy and hassle-free. Follow these steps to book a test: 1). Visit the Lab Tests section on the Tata 1mg website. 2). Add the test you want to the cart. 3). Pick a time and date slot according to your convenience; however, do consider the necessary prerequisites while scheduling a test. 4). You will receive a notification with all the details once the test is scheduled.
Tata 1mg Labs is a pocket-friendly platform for booking lab tests in Indore. The PR3 (c-ANCA) test is available at an affordable price of Rs. 1349.
At Tata 1mg Labs, we understand the importance of timely results. We strive to provide fast turnaround times for test results, allowing you to get the information you need promptly. On average, we take 60 hours to provide the reports of the PR3 (c-ANCA) test in Indore.
Content created by
Written by:
Dr. Lipika Khurana
PGDHHM, BDS
Reviewed by:
Dr. Swati Gupta (Anand)
MBBS, MD Lab Medicine
Want to know moreRead our editorial policy
Last Updated14th Nov 2025

PR3 (c-ANCA) test price for other cities

Price inNew DelhiRs. 1329
Price inGurgaonRs. 1329
Price inBangaloreRs. 1629
Price inHyderabadRs. 1900
Price inPuneRs. 1709

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PR3 (c-ANCA)