
MPN Panel 8 near me in Navi Mumbai







The MPN (Myeloproliferative Neoplasm) panel by PCR is a molecular diagnostic test that detects specific mutations associated with MPNs. This panel includes the analysis of BCR-ABL, JAK2 exon 12-14, and EPO by CLIA. The test utilizes PCR (Polymerase Chain Reaction) technology to amplify and identify these mutations in the patient's DNA. Detection of these mutations aids in the diagnosis, classification, and monitoring of MPNs, such as chronic myeloid leukemia (CML), polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF), enabling more accurate treatment decisions and patient management.






What does MPN Panel 8 measure?
Contains 2 testsThe Erythropoietin (EPO)+Jak 2 Exon 12-15 test measures serum erythropoietin (EPO) levels to determine whether red blood cell production is driven by hormones or occurs independently. It also detects mutations in the JAK2 gene (exons 12 to 15), which can cause abnormal activation of the JAK-STAT pathway and lead to myeloproliferative disorders. A low EPO level with a positive JAK2 mutation supports the diagnosis of polycythemia vera, whereas a normal or elevated EPO level with no JAK2 mutation points to a secondary cause, such as chronic hypoxia or kidney disease. By combining hormonal and genetic insights, this test helps accurately differentiate the origin of disease and enables clinicians to develop a personalized treatment plan.
Know more about Erythropoietin (EPO)+Jak 2 Exon 12-15





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