MPN Panel near me in Chennai
The MPN Panel is a molecular diagnostic test that detects specific mutations associated with MPNs. The test utilizes NGS technology to amplify and identify these mutations in the patient's DNA. Detection of these mutations aids in the diagnosis, classification, and monitoring of MPNs, such as chronic myeloid leukemia (CML), polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF), enabling more accurate treatment decisions and patient management. This panel is widely available with Tata 1mg labs at an affordable price in Chennai.
Understanding MPN Panel
Chronic myeloproliferative neoplasms (MPNs) are blood disorders in which the bone marrow produces too many red blood cells, white blood cells, or platelets. The MPN Panel is a comprehensive blood test test used to evaluate genetic changes in blood cells that are characteristic of myeloproliferative neoplasms.
The MPN Panel examines hotspot genes (specific regions of a gene that are frequently mutated), full genes (entire genes sequenced to detect rare or uncommon mutations), and gene fusions (abnormal joining of two genes that can drive disease). This comprehensive analysis is crucial for identifying specific types of myeloproliferative neoplasms (MPNs), including polycythemia vera (PV), essential thrombocythemia (ET), primary myelofibrosis (PMF), and for providing a broader genetic profile that helps in diagnosis and treatment planning.
Doctors may recommend the thi panel if you are experiencing symptoms such as fatigue, weakness, an enlarged spleen, or abnormal blood counts, or if you have a previously diagnosed MPN and need to monitor disease progression or treatment response. It is also advised for individuals with a family history of MPNs or known genetic risk factors. This test helps diagnose specific myeloproliferative neoplasms (MPNs), including chronic myeloid leukemia (CML), polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF), differentiate between types of MPN for appropriate treatment, monitor response to therapy, and assess the risk of developing complications.
For this test, it is important to submit the clinical history, histopathology report, previous test results, and a doctor’s prescription at the time of sample collection. The Tata 1mg consolidated Test Requisition Form (TRF) must also be duly filled and submitted.
Lab test results may vary across different laboratories. Abnormal test results require an expert interpretation. Therefore, never try to self-medicate at home based solely on these results, and always consult a doctor for proper understanding of the test results.
What does MPN Panel measure?
Contains 3 testsThe MPN Panel detects genetic mutations and gene fusions that are important in diagnosing and classifying myeloproliferative neoplasms (MPNs). The test is divided into the following categories:
Hotspot Genes: These genes are frequently mutated in MPNs and related blood disorders, and their analysis helps identify abnormal blood cell production:-
ABL1, CBL, FLT3, IDH1, IDH2, JAK2, KIT, MPL, NPM1, NRAS, SF3B1, SRSF2, U2AF1, DNMT3A
Full Genes: These genes are fully sequenced to detect a broader range of mutations, which can aid in disease classification, prognosis, and monitoring:
ASXL1, CALR, EZH2, IKZF1, NF1, RUNX1, SH2B3, STAG2, TET2, TP53, ZRSR2
Gene Fusions: Certain gene rearrangements (fusions) are analyzed because they can drive abnormal blood cell growth and impact disease behavior:-
ETV6, JAK2, KMT2A, RUNX1
By examining these hotspot genes, full genes, and gene fusions, the test provides a comprehensive molecular profile, helping doctors accurately diagnose, classify, and manage MPNs.
MPN Panel test price for other cities
| Price in | Ahmedabad | Rs. 19950 |
| Price in | Allahabad | Rs. 19950 |
| Price in | Asansol | Rs. 19950 |
| Price in | Bangalore | Rs. 19950 |
| Price in | Bhopal | Rs. 19950 |
How does home sample collection work?
Easy online booking
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Safe Sample Collection
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Sample received at lab
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