MPN Panel

Also referred as

Myeloproliferative Neoplasm Panel

For men & women

Earliest reports in

432 hours

Contains

3 tests

Test price:

₹19950

~~₹21000~~

5% off

Know more about this test

The MPN Panel is a combination of genetic tests that detects mutations and gene fusions associated with myeloproliferative neoplasms (MPNs), a type of blood cancer. It helps doctors diagnose and classify MPNs, plan treatment, and monitor disease progression.

Samples required

Blood

Find out

Why is this test booked?

Preparation for this test

Sample Collection

Who will collect your samples?

Test conducted by

Core Diagnostics Private Limited

ISO, CAP, NABL certified

Know More

Know more about lab

Core Diagnostics Private Limited

ISO, CAP, NABL certified

About this lab

We at CORE Diagnostics are a renowned pathology testing laboratory & a premier institute in the country capable of providing varied diagnostic tests & facilities in the field of laboratory medicine and have established state-of-art testing facilities in Gurgaon. We are a Clinical laboratory focused on Next Generation Diagnostics for disease stratification and therapy selection. We are focused on bringing the most advanced testing techniques and expertise to India and aim to become the destination for all your high-end diagnostic needs.

Understanding MPN Panel

Chronic myeloproliferative neoplasms (MPNs) are blood disorders in which the bone marrow produces too many red blood cells, white blood cells, or platelets. The MPN Panel is a comprehensive blood test test used to evaluate genetic changes in blood cells that are characteristic of myeloproliferative neoplasms.

The MPN Panel examines hotspot genes (specific regions of a gene that are frequently mutated), full genes (entire genes sequenced to detect rare or uncommon mutations), and gene fusions (abnormal joining of two genes that can drive disease). This comprehensive analysis is crucial for identifying specific types of myeloproliferative neoplasms (MPNs), including polycythemia vera (PV), essential thrombocythemia (ET), primary myelofibrosis (PMF), and for providing a broader genetic profile that helps in diagnosis and treatment planning.

Doctors may recommend the thi panel if you are experiencing symptoms such as fatigue, weakness, an enlarged spleen, or abnormal blood counts, or if you have a previously diagnosed MPN and need to monitor disease progression or treatment response. It is also advised for individuals with a family history of MPNs or known genetic risk factors. This test helps diagnose specific myeloproliferative neoplasms (MPNs), including chronic myeloid leukemia (CML), polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF), differentiate between types of MPN for appropriate treatment, monitor response to therapy, and assess the risk of developing complications.

For this test, it is important to submit the clinical history, histopathology report, previous test results, and a doctor’s prescription at the time of sample collection. The Tata 1mg consolidated Test Requisition Form (TRF) must also be duly filled and submitted.

Lab test results may vary across different laboratories. Abnormal test results require an expert interpretation. Therefore, never try to self-medicate at home based solely on these results, and always consult a doctor for proper understanding of the test results.

What does MPN Panel measure?

Contains 3 tests

The MPN Panel detects genetic mutations and gene fusions that are important in diagnosing and classifying myeloproliferative neoplasms (MPNs). The test is divided into the following categories:

Hotspot Genes: These genes are frequently mutated in MPNs and related blood disorders, and their analysis helps identify abnormal blood cell production:-

ABL1, CBL, FLT3, IDH1, IDH2, JAK2, KIT, MPL, NPM1, NRAS, SF3B1, SRSF2, U2AF1, DNMT3A

Full Genes: These genes are fully sequenced to detect a broader range of mutations, which can aid in disease classification, prognosis, and monitoring:

ASXL1, CALR, EZH2, IKZF1, NF1, RUNX1, SH2B3, STAG2, TET2, TP53, ZRSR2

Gene Fusions: Certain gene rearrangements (fusions) are analyzed because they can drive abnormal blood cell growth and impact disease behavior:-

ETV6, JAK2, KMT2A, RUNX1

By examining these hotspot genes, full genes, and gene fusions, the test provides a comprehensive molecular profile, helping doctors accurately diagnose, classify, and manage MPNs.

Hotspot genes: ABL1, CBL, FLT3, IDH1, IDH2, JAK2, KIT, MPL, NPM1, NRAS,SF3B1, SRSF2, U2AF1,DNMT3A

Full genes: ASXL1, CALR, EZH2, IKZF1, NF1, RUNX1, SH2B3, STAG2, TET2, TP53, ZRSR2

Gene Fusions: ETV6, JAK2, KMT2A ,RUNX1

Test Information is reviewed by: Dr. Swati Gupta (Anand), MBBS, MD Lab Medicine and written by Dr. Lipika Khurana, BDS, PGDHHM . The test details are for information purpose only. Consult a doctor before taking any test. Last updated on: 16th Apr 2026

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MPN Panel test price for other cities

Price in	Chennai	Rs. 19950
Price in	Kolkata	Rs. 19950
Price in	Allahabad	Rs. 19950
Price in	Bangalore	Rs. 19950
Price in	Bhopal	Rs. 19950

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Our phlebotomists follow strict safety protocols to collect samples safely at home and on time.

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Samples are transported securely to our accredited labs with world-class machines for testing by qualified experts.

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FAQs related to MPN Panel

What is the MPN Panel?

It is a genetic test that examines hotspot genes, full genes, and gene fusions associated with myeloproliferative neoplasms (MPNs), helping doctors diagnose, classify, and manage these blood disorders.

Who should get this test?

Individuals with persistently high blood counts; People suspected to have MPNs such as polycythemia vera (PV), essential thrombocythemia (ET), or primary myelofibrosis (PMF); Patients with a family history of MPNs or known genetic risk factors

How is the MPN Panel performed?

A phlebotomist will clean your skin using an antiseptic alcohol cotton swab or wipe and take blood samples from your vein using a needle. The blood sample will be stored safely and transported to the laboratory for analysis.

Do I need to fast before taking the MPN Panel?

No fasting is required for this test. You can schedule it at your convenience without avoiding food or water beforehand.

Are there any risks associated with this test?

The test is generally safe. You may experience slight discomfort or bruising at the blood collection site, but serious complications are extremely rare.

What do abnormal results mean?

Abnormal results indicate the presence of specific gene mutations or fusions associated with MPNs. Your doctor may use this information to diagnose the type of MPN, plan treatment, and monitor disease progression.

What are common symptoms of MPNs?

Symptoms may include fatigue, weakness, night sweats, headaches, weight loss, enlarged spleen, or blood clotting problems. Early stages may be asymptomatic and detected during routine blood tests.

Can MPNs be cured?

There is currently no complete cure for most MPNs. Early diagnosis and treatment can control symptoms, prevent complications, and improve quality of life. Targeted therapies or bone marrow transplantation may be options depending on disease type and stage.

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References

Other tests

Recommended for everyone

This package is designed with everyone’s overall health considerations in mind, offering assessments to address a wide range of wellness needs.

Package can be booked by :

Men

Women

Contains 3 tests

Hotspot genes: ABL1, CBL, FLT3, IDH1, IDH2, JAK2, KIT, MPL, NPM1, NRAS,SF3B1, SRSF2, U2AF1,DNMT3A

Full genes: ASXL1, CALR, EZH2, IKZF1, NF1, RUNX1, SH2B3, STAG2, TET2, TP53, ZRSR2

Gene Fusions: ETV6, JAK2, KMT2A ,RUNX1

Report delivery

Standard time

432 hrs

For slots after 11 AM, report will be delivered in 432 hours.

Samples required

Blood

Our phlebotomist will draw a blood sample, typically from a vein in your inner elbow.

Preparations

Provide your clinical history, previous test reports, and a valid prescription. Tata 1mg consolidated TRF to be filled.

Why is this test booked?

If you have symptoms of MPN, such as fatigue, weakness, night sweats, or an enlarged spleen.

If your blood counts are abnormal or routine tests suggest a myeloproliferative disorder.

To monitor disease progression or response to treatment in previously diagnosed MPN patients.

If you have a family history of MPNs or known genetic risk factors.

To diagnose specific types of MPNs, such as polycythemia vera (PV), essential thrombocythemia (ET), or primary myelofibrosis (PMF).

To differentiate between MPN subtypes for appropriate treatment planning.

To assess the risk of developing complications associated with MPNs.

Who's behind your sample collection?

MEET YOUR PHLEBO

Certified & experienced professionals

Tata 1mg phlebotomists are DMLT / B.Sc MLT certified and have 1+ years of experience

Best in-class collections

Tata 1mg phlebotomists are trained for painless, single-prick hygienic sample collection

Comprehensive expertise

Other than sample collection, our phlebos are also skilled in first aid, ECG & BP monitoring

WHAT OUR CUSTOMERS ARE SAYING

Pain free blood collection

~ Vaghela Sagar Shashikantbhai

Excellent service

~ JITENDER KUMAR

Pain free collection

~ Sandugade Subhash Tukaram

Pain free collection

~ Phartale Sachin Ashok

Technician was great..

~ Saurav Choudhury

Very polite

~ Sadhana Kumari

Good skill for sample collection

~ Pawan Kumar Sah

Very gentle

~ Divya Chawla

Process very fast and good 👍

~ Jadav Savjibhai Samjibhai

Thank you for pain free collection

~ Dattatray Nanabhau Gawandi