Microsatellite Instability (MSI) near me in Indore
The Microsatellite Instability (MSI) detects genetic changes in specific repetitive DNA sequences within tumor cells. These changes occur when the DNA mismatch repair (MMR) system fails to work properly. The test helps identify conditions such as Lynch syndrome (Hereditary Non-Polyposis Colorectal Cancer) and guides treatment decisions. This molecular diagnostic test evaluates the stability of microsatellites to assess MMR function. Defects in MMR genes cause errors to accumulate in DNA, which is commonly associated with Lynch syndrome (Hereditary Non-Polyposis Colorectal Cancer, HNPCC), the most frequent inherited cause of colorectal cancer. MSI is also linked to an increased risk of other cancers, including endometrial, gastric, ovarian, and urinary tract cancers. This panel is widely available with Tata 1mg labs at an affordable price in Indore.
Disclaimer: In no event shall the liability of TATA 1MG exceed the amount of the actual cost of test charges incurred by the customer as stated on the invoice issued by Tata 1mg.
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- Battaglin F, Naseem M, Lenz HJ, Salem ME. Microsatellite instability in colorectal cancer: overview of its clinical significance and novel perspectives. Clin Adv Hematol Oncol. 2018 Nov;16(11):735-745. PMID: 30543589; PMCID: PMC7493692. [Accessed 21 Oct 2025]. Available From:
- Li K, Luo H, Huang L, Luo H, Zhu X. Microsatellite instability: a review of what the oncologist should know. Cancer Cell Int. 2020 Jan 13;20:16. [Accessed 21 Oct 2025]. Available From:
- Bhattacharya P, Leslie SW, McHugh TW. Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer) [Updated 2024 Jun 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from:
- Sherman S, Ojha SK, Menon G, et al. Hereditary Nonpolyposis Colon Cancer (Lynch Syndrome) [Updated 2025 Jan 19]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from:
