Jo-1 antibody near me in Pune
The Jo-1 antibody test is a blood test that detects Jo-1 autoantibodies, which are strongly associated with autoimmune conditions like polymyositis and dermatomyositis. These conditions can cause progressive muscle weakness and, in the case of dermatomyositis, distinctive skin rashes. The test helps in diagnosing, monitoring, and managing such autoimmune disorders. This test is widely available in Pune with Tata 1mg labs at an affordable price.
The Jo-1 antibody test is usually recommended when a patient presents with unexplained muscle weakness, fatigue, joint pain, difficulty swallowing, or skin rashes. It is also useful in assessing patients with interstitial lung disease, which can sometimes occur alongside these autoimmune disorders. Early detection of Jo-1 antibodies can help guide treatment decisions and improve disease management.
No special preparation is needed for getting the Jo-1 antibody test done. However, it is preferred that you share your clinical history, current medications, and supplement use with your doctor before giving the sample, as these may influence the results.
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- Zampieri S, Ghirardello A, Iaccarino L, Tarricone E, Gambari PF, Doria A. Anti-Jo-1 antibodies. Autoimmunity. 2005 Feb;38(1):73-8. [Accessed 23 Sep. 2025]. Available from:
- Anti-synthetase syndrome in ANA and anti-Jo-1 negative patients presenting with idiopathic interstitial pneumonia [Internet]. ScienceDirect; [Accessed 23 Sep. 2025]. Available from:
- Honda M, Shimizu F, Sato R, Mizukami Y, Watanabe K, Takeshita Y, Maeda T, Koga M, Kanda T. Jo-1 Antibodies From Myositis Induce Complement-Dependent Cytotoxicity and TREM-1 Upregulation in Muscle Endothelial Cells. Neurol Neuroimmunol Neuroinflamm. 2023 May 5;10(4):e200116. [Accessed 23 Sep. 2025]. Available from: