
IgG Subclass 4 (IgG4) near me in Pune









The IgG Subclass 4 (IgG4) test measures the level of immunoglobulin G subclass 4 (IgG4) antibodies in the blood, a specific subtype of IgG involved in immune regulation. This test is primarily used to support the clinical evaluation of IgG4-related disease, a chronic immune-mediated condition characterized by inflammation, fibrosis, and involvement of multiple organs. Elevated IgG4 levels are commonly associated with conditions such as autoimmune pancreatitis and sclerosing cholangitis, and may also be observed in certain allergic or inflammatory conditions. The test is widely available with Tata 1mg labs in Pune at an affordable price.








What does IgG Subclass 4 (IgG4) measure?
The IgG Subclass 4 (IgG4) test measures the level of immunoglobulin G subclass 4 (IgG4) antibodies in the blood. IgG4 is one of the four subclasses of IgG antibodies and plays a role in regulating immune responses. Unlike some other antibodies that strongly trigger inflammation, IgG4 is often involved in modulating immune activity during long-term or repeated immune stimulation.
Abnormal or elevated IgG4 levels have been associated with certain immune-mediated and inflammatory conditions, including IgG4-related disease. However, raised IgG4 levels are not specific to a single condition and must be interpreted along with clinical symptoms, imaging findings, and other laboratory tests. For this reason, IgG4 testing is used as a supportive test to aid diagnosis and monitor disease activity rather than as a standalone test.





FAQs related to IgG Subclass 4 (IgG4) in Pune
- Shi LL, Xiong P, Yang M, Ardicli O, Schneider SR, Funch AB, Kiykim A, Lopez J, Akdis CA, Akdis M. Role of IgG4 Antibodies in Human Health and Disease. Cells. 2025 Apr 25;14(9):639. [Accessed 17 June. 2025]. Available from:
- Monach PA. IgG4-related Disease: 2013 Update. Curr Treat Options Cardiovasc Med. 2013 Apr;15(2):214-23. [Accessed 17 June. 2025]. Available from:
- Abraham M, Khosroshahi A. Diagnostic and treatment workup for IgG4-related disease. Expert Rev Clin Immunol. 2017 Sep;13(9):867-875. [Accessed 17 June. 2025]. Available from:
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