Hyperthyroidism / Graves Disease Panel near me in Dehradun

Thyroxine (T4) and Triiodothyronine (T3) are thyroid hormones that help regulate metabolism and energy levels. On the other hand, the pituitary gland produces thyroid-stimulating hormone (TSH) and stimulates the thyroid gland to produce T3 and T4 hormones. T3 and T4 circulate in the blood in two forms: bound (attached to proteins) and free (does not attach to any protein). The Thyroid Profile Free (FT3, FT4 & TSH) measures the free or active form of these hormones.

The serum levels of the thyroid hormones and TSH have an inverse relationship, i.e., low T4 and T3 (as observed in hypothyroidism) and high T4 and T3 (as seen in hyperthyroidism) levels are associated with high and low TSH levels, respectively.

The TSH Receptor Antibodies test measures the presence and levels of specific antibodies known as TSH or Thyrotropin Receptor Antibody. These antibodies bind to the receptors on thyroid cells normally activated by thyroid stimulating hormone (TSH) and their presence usually indicates Grave’s disease, an autoimmune thyroid disorder. In Graves’ disease, an antibody called thyroid-stimulating immunoglobulin (TSI) binds to the TSH receptor and mimics the action of TSH. This causes constant stimulation of the thyroid gland, prompting it to release too much thyroid hormone. Elevated levels of these antibodies indicate an autoimmune response against the thyroid gland, which can help diagnose and monitor the relapse of Grave’s disease.