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Written by
Dr. Shreya Gupta
BDS, MDS - Oral and Maxillofacial Pathology
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Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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HRDTrack Test in Kolkata

You need to provide
Tissue Block : FFPE ( Formalin-Fixed, Paraffin-Embedded)
This test is for
Male, Female
Test Preparation
  1. Clinical history is required.

Understanding HRDTrack Test in Kolkata

What is HRDTrack Test in Kolkata?

The HRDTrack test is a crucial diagnostic tool used in the field of oncology to assess the status of Homologous Recombination Deficiency (HRD) in patients. HRD is a biological phenomenon where cells fail to effectively repair DNA double-strand breaks, leading to an increased occurrence of genomic alterations. While the HR pathway, which includes genes like BRCA1/2, is essential for accurate DNA repair, HRD can occur even without mutations in these genes. Remarkably, over 50% of high-grade serous ovarian cancer patients exhibit HR deficiency, with only approximately 20% of them carrying BRCA1/2 mutations.

This test determines HRD status by analyzing genome-wide aberrations resulting from defects in the Homologous Recombination Repair (HRR) pathway and pathogenic mutations in BRCA1 and BRCA2 genes. It begins by extracting DNA from FFPE tissue samples and preparing targeted Next-generation sequencing libraries with Unique Molecular Identifiers (UMIs). These enriched libraries are then sequenced using Illumina sequencing platforms, such as Novaseq, following rigorous quality control checks. The resulting sequencing data is used to identify mutations in BRCA1 and BRCA2 genes and compute the HRD status.

 The results of this test serve as a valuable aid in determining the eligibility of patients for specific treatments, such as Poly-ADP Ribose inhibitors, by providing critical insights into HRD status and genomic stability. This diagnostic tool plays a pivotal role in personalized medicine, helping healthcare professionals make informed decisions about treatment strategies for cancer patients.

Disclaimer: In no event shall the liability of TATA 1MG exceed the amount of actual cost of test charges incurred by the customer as stated on the invoice issued by Tata 1mg.

HRDTrack Test test price for other cities

Price inAgraRs. 88785
Price inAhmedabadRs. 88785
Price inAllahabadRs. 88785
Price inAsansolRs. 88785
Price inBangaloreRs. 88785
+ more

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Reports are sent to your email. A free doctor follow up is provided to understand the report better.

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