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HE4 With ROMA Index in Mumbai

Also known as HE4, Human Epididymis Protein 4 CA125, Cancer Antigen 125 ROMA, Risk of Ovarian Malignancy Algorithm, ROMA Score
HE4 With ROMA Index in Mumbai Includes 3 testsView All
You need to provide
Blood
This test is for
Female
Test Preparation
  1. Provide brief clinical history/doctor's prescription at the time of sample collection.
  2. Provide date of last menstrual period (LMP).
  3. Provide menopausal status of the patient.

Understanding HE4 With ROMA Index in Mumbai


What is HE4 With ROMA Index in Mumbai?

HE4 With ROMA Index is a diagnostic test to assess the risk of epithelial ovarian cancer in women and is available with Tata 1mg in Mumbai. This test combines the measurement of HE4 (Human epididymis protein 4), a protein produced by cells in the ovaries and the lining of the respiratory tract; CA-125 (cancer antigen-125), a tumor marker that is often elevated in women with ovarian cancer; and the Risk of Ovarian Malignancy Algorithm (ROMA) index along with other factors like the woman’s age and menopausal status for calculation of a numerical score. This combination of biomarkers provides valuable information for the early detection and management of ovarian cancer. 

HE4 With ROMA Index test is available in Mumbai at an affordable price with Tata 1mg labs and is recommended for women who are above 18 years of age, have an adnexal mass for which surgery is planned, and who have not yet been referred to a doctor who specializes in diagnosing and treating cancer (oncologist). 

No special preparation is required for this test. You can eat and drink as per your routine. However, it is important to provide a brief clinical history or doctor's prescription at the time of sample collection. Additionally, provide the date of your last menstrual period (LMP) or indicate the menopausal status of the patient.

What does HE4 With ROMA Index measure?

Contains 3 tests

The HE4 With ROMA Index test measures key biomarkers to assess the risk of epithelial ovarian cancer. It includes Human Epididymis Protein 4 (HE4), CA 125, and evaluation of the Risk of Ovarian Malignancy Algorithm (ROMA) index. In cases of ovarian cancer, the levels of HE4 and CA 125 are often elevated. The ROMA index combines HE4 levels with CA 125 along with other factors like the woman’s age and menopausal status for the calculation of a numerical score. This combination of biomarkers and clinical history enhances the accuracy of HE4 With ROMA Index test in predicting the presence of epithelial ovarian cancer, particularly in its early stages. This test is particularly useful in women with pelvic masses who have not yet undergone surgery.

What sets the HE4 With ROMA Index test apart is its ability to provide a nuanced assessment of epithelial ovarian cancer risk. While CA 125 alone can sometimes yield false positive results due to its elevation in other conditions like endometriosis, HE4 offers added specificity and precision. Moreover, the ROMA index takes into account individual factors like age and menopausal status, further refining the risk assessment. This comprehensive approach not only helps in the early detection of epithelial ovarian cancer but also helps differentiate between malignant (cancerous) and benign (non-cancerous) ovarian masses, guiding doctors in making informed decisions regarding further diagnostic workup and determining whether a woman with a pelvic mass is at high or low risk for ovarian cancer before surgery, which can guide treatment decisions and help in planning surgery. 

HE4 - Human Epididymis Protein 4

ROMA Value

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CA125 (Cancer Antigen 125)

CA125 is a protein found in most ovarian cancer cells and some normal tissues. A CA125 (Cancer Antigen 125) test is commonly advised to detect ovarian cancer by measuring the amount of CA125 protein in the blood. A deranged level of CA125 antigen may indicate the presence of certain cancers, primarily ovarian cancer or other non-cancerous conditions, including endometriosis, pelvic inflammatory disease, ovarian cysts, etc.

Know more about CA125 (Cancer Antigen 125)

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about HE4 With ROMA Index in Mumbai


Frequently Asked Questions about HE4 With ROMA Index in Mumbai

Q. What is the HE4 With ROMA Index test for?

The HE4 With ROMA Index test is used to assess the risk of epithelial ovarian cancer in women. It measures the level of Human Epididymis Protein 4 (HE4) and CA 125 in combination with the Risk of Ovarian Malignancy Algorithm (ROMA) index. This test is valuable for early detection and management of ovarian cancer. Also, it helps monitoring ovarian cancer treatment and recurrence, as well as screening of high-risk individuals.

Q. Who should undergo the HE4 With ROMA Index test?

This test is recommended for women who have a pelvic mass or other symptoms suggestive of ovarian cancer, and for women with a family history or other risk factors for ovarian cancer.

Q. How is a HE4 With ROMA Index test performed?

A phlebotomist (a trained professional to perform blood draws) will clean your skin using an antiseptic alcohol cotton swab or wipe and take blood samples from your vein using a needle. The blood sample will be stored safely and transported to the laboratory for analysis.

Q. Can the HE4 With ROMA Index test be used to monitor treatment?

Yes, the HE4 With ROMA Index test can be used to monitor response to treatment in women diagnosed with epithelial ovarian cancer.

Q. Does Tata 1mg Labs offer a HE4 With ROMA Index test in Mumbai?

Yes, you can book the HE4 With ROMA Index test in Mumbai with Tata 1mg Labs. The test can be booked easily, is affordable, and comes with an easy-to-understand report.

Q. Is home sample collection facility available for HE4 With ROMA Index test in Mumbai with Tata 1mg Labs?

Yes, home sample collection for HE4 With ROMA Index test is readily available in Mumbai. Tata 1mg Labs allows you to choose a date and time that suits your schedule for sample collection.

Q. How can I schedule the HE4 With ROMA Index test with Tata 1mg Labs in Mumbai?

If you want to schedule the HE4 With ROMA Index test with Tata 1mg Labs in Mumbai, the procedure is fairly easy and hassle-free. Follow these steps to book a test: 1). Visit the Lab Tests section on the Tata 1mg website. 2). Add the test you want in the cart. 3). Pick a time and date slot according to your convenience; however, do consider the necessary prerequisites while scheduling a test. 4). You will receive a notification with all the details once the test is scheduled.

Q. What is the price of HE4 With ROMA Index test at Tata 1mg Labs in Mumbai?

Tata 1mg Labs is a pocket-friendly platform for booking lab tests in Mumbai. The HE4 With ROMA Index test is available at an affordable price of Rs. 2299.

Q. How can I get my HE4 With ROMA Index test report from Tata 1mg?

The e-report of your HE4 With ROMA Index test can be found on the Tata 1mg app in downloadable PDF form. This allows you to access your test results at convenience and securely share them with your healthcare provider for further consultation and guidance regarding your overall health. You can also opt for a hard copy of the reports at a minimal price.

Q. What is the estimated turnaround time for the results of {test-name} test in Mumbai?

At Tata 1mg Labs, we understand the importance of timely results. We strive to provide fast turnaround times for test results, allowing you to get the information you need promptly. On average, we take 144 hours to provide the reports of HE4 With ROMA Index test in Mumbai.
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HE4 With ROMA Index test price for other cities


Price inKolkataRs. 2299
Price inNew DelhiRs. 2299
Price inGurgaonRs. 2299
Price inBangaloreRs. 2299
Price inThaneRs. 2299
+ more

Book HE4 With ROMA Index at-home

Easy online booking
Search for tests and packages, book a time and select address for seamless at-home lab tests.
Live tracking of phlebotomist
Stay informed with live tracking of our phlebotomist's location for seamless sample collection.
Safe collection
Our phlebotomists follow strict safety protocols to collect samples at home on time.
Sample received at lab
Your sample is bought to our laboratory for testing by our qualified experts.
Quick reports, free follow up
Reports are sent to your email. A free doctor follow up is provided to understand the report better.

References

  1. Wei SU, Li H, Zhang B. The diagnostic value of serum HE4 and CA-125 and ROMA index in ovarian cancer. Biomed Rep. 2016 Jul;5(1):41-44. [Accessed 23 Apr. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906902/ External Link
  2. Van Gorp T, Cadron I, Despierre E, Daemen A, Leunen K, Amant F, Timmerman D, De Moor B, Vergote I. HE4 and CA125 as a diagnostic test in ovarian cancer: prospective validation of the Risk of Ovarian Malignancy Algorithm. Br J Cancer. 2011 Mar 1;104(5):863-70. [Accessed 23 Apr. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048204/ External Link
  3. Kumar V, Rajan S, Gupta S, Akhtar N, Sharma S, Sinha P, Misra S, Chaturvedi A. Diagnostic Value of Risk of Malignancy Algorithm (ROMA) in Adnexal Masses. J Obstet Gynaecol India. 2020 Jun;70(3):214-219. [Accessed 23 Apr. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239964/ External Link
  4. What are the risk factors for ovarian cancer? [Internet]. CDC; 14 June 2023 [Accessed 23 Apr. 2024]. Available from: https://www.cdc.gov/cancer/ovarian/basic_info/risk_factors.htmExternal Link
  5. Risks and causes of ovarian cancer [Internet]. Cancer Research UK: 28 Feb. 2022 [Accessed 23 Apr. 2024]. Available from: https://www.cancerresearchuk.org/about-cancer/ovarian-cancer/risks-causes#:~:text=As%20with%20most%20cancers%2C%20ovarian,between%2075%20and%2079%20yearsExternal Link
  6. Can Ovarian Cancer Be Prevented? [Internet]. American Cancer Society: 11 Apr. 2018 [Accessed 23 Apr. 2024]. Available from: https://www.cancer.org/cancer/types/ovarian-cancer/causes-risks-prevention/prevention.html#:~:text=Some%20risk%20factors%20for%20ovarian,hormone%20replacement%20therapy%20after%20menopause External Link
  7. Ovarian cancer causes [Internet]. NHS; 24 Jan. 2022 [Accessed 23 Apr. 2024]. Available from: https://www.nhs.uk/conditions/ovarian-cancer/causes/External Link
  8. Cancer Stat Facts: Ovarian Cancer [Internet]. NIH; National Cancer Institute. [Accessed 23 Apr. 2024]. Available from: https://seer.cancer.gov/statfacts/html/ovary.html External Link

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