geneCORE Immunotherapy Panel-1 near me in Chennai

For men & women

Earliest reports in

768 hours

Contains

3 tests

Know more about this test

geneCORE Immunotherapy panel-1 that contains TMB (Tumor Mutational Burden), PD-L1 (22C3 Dako) expression, and MSI (Microsatellite instability) testing, is a comprehensive molecular diagnostic panel. It uses next-generation sequencing (NGS) technology to analyze 161 genes associated with various cancers. The panel assesses genetic alterations, TMB levels, PD-L1 (22C3 Dako) expression, and MSI status simultaneously. This integrated approach provides valuable information about the tumor's genetic profile, immune microenvironment, and DNA repair capacity. The results help guide personalized treatment decisions, including targeted therapies, immunotherapies, and identifying patients for clinical trials, based on the combined assessment of genetic alterations, immune checkpoint status, and DNA repair capability.

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Samples required

Tissue Block : FFPE ( Formalin-Fixed, Paraffin-Embedded) & Blood

Preparation for this test

Sample Collection

Who will collect your samples?

What does geneCORE Immunotherapy Panel-1 measure?

Contains 3 tests

PDL-1 22C3 Dako

The PDL-1 22C3 Dako test measures the level of PD-L1 protein expression on tumor cells using IHC with the Dako 22C3 antibody clone. The results are reported as a Tumor Proportion Score (TPS), which represents the percentage of tumor cells showing PD-L1 staining. The score helps doctors understand whether a patient is likely to respond to immunotherapy medicines such as pembrolizumab (Keytruda) and plan the most suitable treatment approach.

Know more about PDL-1 22C3 Dako

TMB

MSI

Content created by

Dr. Swati Gupta (Anand)

MBBS, MD Lab Medicine

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