
Factor V Leiden Mutant Detection (G1691A Mutation) near me in Kolkata









The Factor V Leiden Mutant Detection (G1691A Mutation) test is a blood test that identifies the presence of a specific genetic mutation called factor V Leiden. This mutation can increase the risk of abnormal blood clot formation, helping doctors evaluate the likelihood of venous thrombosis and related conditions. It is widely available with Tata 1mg labs at an affordable price in Kolkata.








What does Factor V Leiden Mutant Detection (G1691A Mutation) measure?
The Factor V Leiden Mutant Detection (G1691A Mutation) test determines whether a person carries the specific genetic change in the factor V gene known as the G1691A mutation. This mutation alters the way factor V functions by making it resistant to inactivation by activated protein C (APC), a natural regulator that normally helps control clot formation. When factor V cannot be properly switched off, the balance between clot formation and breakdown is disrupted, leading to an increased tendency for abnormal blood clots to develop in the veins.
By detecting the presence or absence of this mutation, the test helps doctors determine an individual’s inherited risk of venous thrombosis, including deep vein thrombosis (DVT) and venous thromboembolism (VTE). It also provides useful information for patients with a family history of clotting disorders or those with unexplained episodes of thrombosis. Identifying this genetic risk factor allows healthcare providers to recommend preventive measures, lifestyle modifications, or medical treatment to reduce the likelihood of future clot-related complications.





FAQs related to Factor V Leiden Mutant Detection (G1691A Mutation) in Kolkata
- Oh H, Smith CL. Evolving methods for single nucleotide polymorphism detection: Factor V Leiden mutation detection. J Clin Lab Anal. 2011;25(4):259-88. [Accessed 24 Sep. 2025]. Available From:
- Pastori D, Menichelli D, Valeriani E, et al. Factor V Leiden Thrombophilia. 1999 May 14 [Updated 2024 May 16]. In: Adam MP, Feldman J, Mirzaa GM, et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2025. Available from:
- Albagoush SA, Koya S, Chakraborty RK, et al. Factor V Leiden Mutation. [Updated 2023 Apr 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from:
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