Double Marker Test- First Trimester near me in Jodhpur
The Double Marker Test- First Trimester also known as a dual marker test, assesses specific biomarkers in a pregnant woman’s blood. It is done during the first trimester of pregnancy, usually between 11-13 weeks. This test provides information about the risk of certain birth defects such as Down syndrome (Trisomy 21), Edward syndrome (Trisomy 18), and Patau syndrome (Trisomy 13) in the developing fetus. It is available at an affordable price in Jodhpur with Tata 1mg labs.
This test measures the levels of two biomarkers in the mother’s blood: human chorionic gonadotropin (hCG) and pregnancy-associated plasma protein A (PAPP-A). The levels of these markers, along with maternal age, gestational age, and ultrasound findings help determine the likelihood of chromosomal abnormalities in the fetus. These abnormalities can lead to various genetic conditions that can affect the baby’s growth and development. Therefore, their early detection is vital for ensuring comprehensive prenatal care and addressing potential health challenges effectively. No special preparation is required for this test.
Understanding Double Marker Test- First Trimester
Prenatal care is necessary to ensure a healthy pregnancy and successful childbirth. Early prenatal screenings identify potential health concerns and guide medical interventions when necessary. The Double Marker Test- First Trimester is essential for early prenatal assessment. It offers invaluable insights into the developing fetus's chromosomal health. The test primarily measures two important biomarkers in the mother’s blood—human chorionic gonadotropin (hCG) and pregnancy-associated plasma protein A (PAPP-A). Both the markers are produced by the fetus and the placenta.
The test also checks if the baby might be at risk for certain genetic problems, especially Down syndrome and Edwards syndrome. These conditions happen when there is an extra copy of chromosome 21 or 18, respectively. They can affect a baby's physical and intellectual development. However, a Double Marker Test-First Trimester is a screening test, not a diagnostic one. It does not determine whether the baby has abnormalities. Instead, it tells whether the unborn baby is at risk of developing certain abnormalities.
The test results are reported as a risk score or probability of the fetus having a chromosomal abnormality. Test results within the expected range suggest a lower risk of chromosomal abnormalities. On the contrary, high levels may indicate a higher risk of chromosomal abnormalities and prompt further testing. Furthermore, a positive screen result (high risk) does not confirm a genetic problem. It may suggest that further testing may be needed to check the baby's health more closely. On the other hand, a negative screen result (low risk) does not guarantee the absence of fetal defects.
In combined risk assessment, the NT scan (a type of ultrasound) is also used to check for conditions like Down syndrome and Patau syndrome. This, along with the mother’s details—such as age, weight, smoking, diabetes, or IVF pregnancy—is included in the overall risk calculation. However, this test does not check for neural tube defects.
No fasting is required for a Double Marker Test-First Trimester. Let the doctor know about any medical conditions, allergies, or medicines being taken, as some medicines may affect the test results and might need to be stopped before getting tested.
Talk to the doctor about the specific test results. The accuracy of the results is subjective to the information provided in the screening form. This information is mandatory for combined risk assessment.
What does Double Marker Test- First Trimester measure?
The Double Marker Test- First Trimester measures two biomarkers in maternal blood associated with chromosomal abnormalities.
a) Free beta-hCG (human chorionic gonadotropin): a hormone made by the placenta shortly after a woman becomes pregnant.
b) PAPP-A (pregnancy-associated plasma protein-A): a protein made by the placenta during early pregnancy. It helps the placenta grow and function properly.
These, along with the USG marker and nuchal translucency (NT) measurement, are effective in Combined screening for Down syndrome and trisomy 13/18 in the fetus. This test only gives the risk for the presence of these chromosomal abnormalities in the developing fetus. A positive screen is not diagnostic but indicates that further evaluation should be considered.
hCG is synthesized by the placenta very early in pregnancy and can be detected in the blood 8-11 days after conception. Higher levels of hCG after 11 weeks of gestation may suggest a higher chance of the baby having Down syndrome. On the other hand, low levels indicate an increased risk for trisomy 18.
PAPP-A is a protein produced by the placenta that is needed for the implantation and maintenance of a healthy placenta (afterbirth). Low levels of PAPP-A before the 14th week of pregnancy suggest an increased risk of fetal chromosomal abnormalities.
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Double Marker Test- First Trimester test price for other cities
Price in | Bangalore | Rs. 2559 |
Price in | Gurgaon | Rs. 2160 |
Price in | New Delhi | Rs. 2160 |
Price in | Pune | Rs. 2339 |
Price in | Mumbai | Rs. 2390 |
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