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CD45 Count

Also referred as
IHC single marker with reporting CD45 LCA
+5
LCA (Leukocyte Common Antigen) immunohistochemistry test
CD45 immunostaining
CD45 antibody staining
CD45 marker test
CD45 immunohistochemistry
For men & women
Earliest reports in
72 hours
Contains
1 test
Test price:
₹2159
₹2200
2% off
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<font color='#864291'>Know more about this test</font>

The CD45 Count test is an immunohistochemistry (IHC) test that detects the presence of CD45, a protein expressed on the surface of all white blood cells (leukocytes). This test helps identify and classify hematopoietic (blood) cells and is widely used in diagnosing various blood cancers, lymphomas, and leukemias.

Samples required
Blood
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Preparation for this test
Sample Collection
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Conducted by
NABL accredited partner lab
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Tata 1mg certified phlebotomists
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NABL accredited partner lab
This is an outsourced test. The sample for this test is collected by Tata 1mg and processed at a NABL-accredited partner lab.
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Understanding CD45 Count

CD45, also known as leukocyte common antigen (LCA), is a protein present on the surface of all mature leukocytes, including lymphocytes (B cells and T cells), monocytes, and granulocytes. It plays a key role in immune cell signaling, activation, and regulation. The CD45 Count test uses specific antibodies in an IHC procedure to detect this protein in the sample, helping doctors confirm whether abnormal cells are of hematopoietic origin.

The CD45 Count test is recommended for individuals with symptoms suggestive of blood cancers or immune system disorders, such as unexplained fatigue, fever, night sweats, weight loss, or enlarged lymph nodes, as well as those with a family history of leukemia or lymphoma or exposure to risk chemicals (e.g., benzene, pesticides). It is useful for diagnosing leukemias and lymphomas, differentiating these blood cancers from non-hematopoietic tumors, determining the stage of certain blood cancers, monitoring treatment effectiveness, and assessing conditions affecting B and T cell activity.

For this test, provide the original histopathology report, clinical history, and any relevant radiological information before the test, as these are important for accurate interpretation. Inform the doctor about all the medications, supplements, and underlying illnesses, as all these factors may affect the test results.

Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Do not self-medicate and always consult a doctor to understand the test results correctly. 

Please note: This is an outsourced test. The sample is collected by TATA 1MG and processed at a NABL accredited partnered lab.

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What does CD45 Count measure?

The CD45 Count test measures the presence and distribution of the CD45 protein on cells in tissue or biopsy samples. CD45 is expressed on nearly all mature leukocytes, including B and T lymphocytes, monocytes, and granulocytes.

By detecting CD45, the test helps doctors determine whether abnormal cells originate from the hematopoietic system (blood-derived) or another tissue type. Positive CD45 expression indicates leukocyte origin, which is critical for diagnosing leukemias, lymphomas, and other blood-related disorders. Absence of CD45 suggests that the abnormal cells are non-hematopoietic, aiding in the differentiation from other cancers. However, results must be interpreted as part of an immunohistochemical marker panel and correlated with morphology, clinical findings, and other investigations. This information supports diagnosis, classification, staging assessment, treatment planning, and monitoring in hematologic malignancies.

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CD45 Count test price for other cities

Price inAllahabadRs. 2089
Price inAligarhRs. 1540
Price inCuttackRs. 1540
Price inAmritsarRs. 1540
Price inAsansolRs. 1540
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FAQs related to CD45 Count

The CD45 Count test measures the presence of the CD45 protein on the surface of white blood cells, including B and T lymphocytes. Detection of CD45 helps determine whether abnormal cells in a tissue sample are of hematopoietic (blood) origin.
Doctors may order this test to: Diagnose leukemias and lymphomas; Differentiate blood cell cancers from other types of tumors; Determine the stage of certain blood cancers; Monitor treatment effectiveness for hematologic malignancies; Assess conditions affecting B and T cell activity.
This test is recommended if you have symptoms such as unexplained fatigue, fever, night sweats, weight loss, or enlarged lymph nodes, or a family history of leukemia or lymphoma.
No fasting is required for this test.
Positive CD45 expression: Indicates the cells are of hematopoietic origin, supporting a diagnosis of leukemia, lymphoma, or other blood cell disorders. Negative CD45 expression: Suggests the cells are not blood-derived, helping differentiate from non-hematopoietic tumors.
Lymphoma is a type of cancer that begins in the lymphatic system, which is part of the body’s immune system. It occurs when abnormal lymphocytes (a type of white blood cell) grow uncontrollably, forming tumors in the lymph nodes, spleen, bone marrow, or other organs.
CD45 is a common marker for all mature leukocytes. Combined with other IHC markers (e.g., CD3 for T cells, CD20 for B cells), it helps pathologists identify the subtype of lymphoma, which is crucial for treatment planning.
Tata 1mg ensures accurate lab test results through certified laboratories that use advanced technology and adhere to stringent quality control measures. This commitment to high standards guarantees reliable results.
Recommended for everyone
This package is designed with everyone’s overall health considerations in mind, offering assessments to address a wide range of wellness needs.
Package can be booked by :
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Contains 1 test
CD45 Count
Report delivery
Standard time
72 hrs
For slots after 11 AM, report will be delivered in 96 hours.
Samples required
Blood
Our phlebotomist will draw a blood sample, typically from a vein in your inner elbow.
Preparations
1
Clinical history is required.
Why is this test booked?
1
To identify the hematopoietic origin of abnormal cells in tissues.
2
To support the diagnosis and classification of leukemias and lymphomas alongside other tests.
3
To distinguish blood cell tumors from non-hematopoietic tumors.
4
To aid staging assessment as part of a complete clinical workup.
5
To support treatment monitoring when interpreted with clinical findings.
6
To assess conditions affecting B and T cell activity.
7
For individuals with symptoms such as unexplained fatigue, fever, night sweats, weight loss, or enlarged lymph nodes.
8
For those with a family history of leukemia or lymphoma.
9
For individuals with a history of exposure to risk chemicals (e.g., benzene, pesticides).
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