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The Beta-2 Microglobulin, Serum test measures the concentration of beta-2-microglobulin in the blood. B2M levels provide insight into both cellular activity and how effectively the kidneys are clearing proteins from the blood. High levels may indicate advanced stages of multiple myeloma, chronic lymphocytic leukemia, kidney disease, or other disorders affecting the immune system. Elevated B2M levels are often associated with poorer prognosis and can guide more aggressive treatment strategies. Low or normal levels typically indicate healthy kidney function and no significant increase in cell turnover from malignancy or immune activation.
By measuring serum B2M, doctors can evaluate disease progression, monitor treatment response, and support diagnosis and prognosis planning for blood cancers and related disorders.




