Autoimmune Liver Diseases IgG Profile, LIA

The Autoimmune Liver Diseases IgG Profile, LIA is a group of blood tests that helps detect several key markers associated with autoimmune liver conditions such as Autoimmune Hepatitis (AIH), Primary Biliary Cholangitis (PBC), and Primary Sclerosing Cholangitis (PSC). These conditions occur when the immune system mistakenly attacks healthy liver cells (producing autoantibodies), leading to inflammation and potential liver damage. The profile involves qualitative measurement of IgG class antibodies against AMA M2, Sp100, LKM1, gp210, LC1 and SLA (antigens) using the line immuno assay (LIA) technique.

Doctors may recommend this test if you have symptoms such as ongoing fatigue, yellowing of the skin or eyes (jaundice), itching, abdominal discomfort, or abnormal liver function test results. The Autoimmune Liver Diseases IgG Profile, LIA helps in confirming the diagnosis, planning appropriate treatment, and monitoring the progression of the condition. Early detection through this test is essential to prevent long-term liver damage and manage symptoms effectively.