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Interpreting Results
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References
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Apolipoprotein - B

Also known as Apolipoprotein B-100
369
You need to provide
Blood
This test is for
Male, Female
Earliest reports in
18 hours
Test Preparation
  1. No special preparation is required.

Understanding Apolipoprotein - B


What is Apolipoprotein - B?

An Apolipoprotein - B test checks the amount of apolipoprotein B (Apo B) in the blood. Apo B is a protein that helps carry cholesterol and fats (triglycerides) through the body. This test is done to check how healthy the heart is. It also helps find out the risk of heart-related problems like heart attack and stroke.

Apolipoprotein B, or Apo - B, is an essential protein that assists in transporting fats within the blood. It is primarily associated with low-density lipoprotein (LDL), or "bad cholesterol." Elevated levels of Apo - B may lead to plaque (fat buildup) in the arteries. This may raise the risk of heart attacks, strokes, and other heart conditions. That is why it is crucial to know the Apo-B level for maintaining heart health.

An Apolipoprotein - B test is useful when routine cholesterol tests are not providing sufficient information regarding heart health. Doctors might order this test if there are symptoms of heart issues, such as chest discomfort, shortness of breath, or rapid heartbeat. It can also be ordered if there are risk factors such as high blood pressure, high cholesterol, obesity, diabetes, or a family history of heart disease. This test also helps assess whether the treatment is effective in individuals with an existing heart condition. It can also be used to diagnose a very rare inherited disorder in which the body does not produce enough Apo B protein.

No fasting is required for this test. Eat and drink normally. Inform the doctor about any medicines or supplements being taken for heart problems, as they may affect test results. Always consult the doctor before making any changes to medication.

Test results can be slightly different depending on the lab. The doctor will explain what the result means. Based on the result, the doctor may plan a treatment or give advice on changes in lifestyle and medicines to manage the condition.

What is Apolipoprotein - B used for?

An Apolipoprotein - B test is done: 

  • To find out if you are at risk for heart problems.
  • If you have health risks like a family history of heart disease, obesity, diabetes, high blood pressure, or have had a heart attack or stroke before.
  • If there are symptoms like chest pain, shortness of breath, or a fast heartbeat.
  • To check how well current heart treatments are working.
  • To monitor how lifestyle changes are helping people with high risk.

What does Apolipoprotein - B measure?

The Apolipoprotein - B test measures the level of Apo B in the blood. The protein helps in transporting fats and cholesterol within the body. Apo B is a central component of some fat-carrying particles in the blood, such as very low-density lipoprotein (VLDL), low-density lipoprotein (LDL), and chylomicrons. It binds to LDL or "bad" cholesterol, which may result in plaque developing in the blood vessels. This accumulation can lead to heart disease, which can become grave or life-threatening if left untreated.

Interpreting Apolipoprotein - B results


Interpretations

Apolipoprotein A1 is the primary protein associated with HDL Cholesterol. It shows a protective function against heart disease. Increased levels are associated with reduced risk of cardiovascular disease.

Apolipoprotein B is the primary protein associated with LDL Cholesterol and plaque formation. Increased levels are associated with increased risk of heart disease.

The ratio of these two correlates with the risk of cardiovascular disease.

Frequently Asked Questions about Apolipoprotein - B


Q. Why is the Apolipoprotein - B test done?

This test is done to check your heart health. It helps find out if you are at risk for heart problems like heart attack, stroke, or blocked arteries.

Q. Do I need to fast before taking the Apolipoprotein - B test?

No, fasting is not required. You can eat and drink as usual before this test.

Q. How is the test performed?

A trained technician will clean the area on your arm and take a blood sample from a vein using a needle. The sample is then sent to the lab for testing.

Q. Are there any risks associated with the Apo B test?

This test is safe and has very few risks. You might feel slight pain or bruising where the needle was inserted, but serious problems are rare.

Q. How frequently should I undergo an Apolipoprotein - B test?

How often you need this test depends on your age, health, lifestyle, and family history. Talk to your doctor to know how often you should take it.

Q. What can be the reasons for low Apo - B levels?

Low Apo - B levels can occur due to liver disease, overactive thyroid, some medicines, poor nutrition, or inherited health conditions.

Q. What does it mean if my Apo-B levels are high?

High Apo - B levels mean you may have more LDL (bad cholesterol) in your blood. This can cause plaque buildup in your arteries and raise your risk of heart disease and stroke.

Q. How can I lower my Apo B levels?

Talk to your doctor for the best advice. You may need medicine, but you can also improve your Apo B levels by eating a healthy diet, exercising regularly, keeping a healthy weight, quitting smoking, limiting alcohol, and reducing stress.

Q. What is atherosclerosis?

Atherosclerosis is a condition where plaque made of cholesterol and other substances builds up in your arteries. This can block blood flow and lead to a heart attack or stroke.
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Apolipoprotein - B test price for other cities


Price inBangaloreRs. 599
Price inMumbaiRs. 369
Price inHyderabadRs. 559
Price inNew DelhiRs. 369
Price inKolkataRs. 369
+ more

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References

  1. Devaraj S, Semaan JR, Jialal I. Biochemistry, Apolipoprotein B. [Updated 2023 May 14]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK538139/External Link
  2. Behbodikhah J, Ahmed S, Elyasi A, Kasselman LJ, De Leon J, Glass AD, Reiss AB. Apolipoprotein B and Cardiovascular Disease: Biomarker and Potential Therapeutic Target. Metabolites. 2021 Oct 8;11(10):690. [Accessed 16 Jan. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540246/#:~:text=A%20more%20recent%20discordance%20analysis,or%20non%2DHDL%2DC. External Link
  3. Apolipoprotein B-100 [Internet]. Healthdirect; [Accessed 16 Jan. 2024]. Available from: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=apolipoprotein_b100 External Link
  4. Contois JH, Langlois MR, Cobbaert C, Sniderman AD. Standardization of Apolipoprotein B, LDL-Cholesterol, and Non-HDL-Cholesterol. J Am Heart Assoc. 2023 Aug;12(15):e030405. [Accessed 16 Jan. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10492988/ External Link
  5. Sniderman AD, Thanassoulis G, Glavinovic T, Navar AM, Pencina M, Catapano A, Ference BA. Apolipoprotein B Particles and Cardiovascular Disease: A Narrative Review. JAMA Cardiol. 2019 Dec 1;4(12):1287-1295. [Accessed 16 Jan. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369156/ External Link
  6. Nayak P, Panda S, Thatoi PK, Rattan R, Mohapatra S, Mishra PK. Evaluation of Lipid Profile and Apolipoproteins in Essential Hypertensive Patients. J Clin Diagn Res. 2016 Oct;10(10):BC01-BC04. [Accessed 16 Jan. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121668/#:~:text=In%20their%20study%2C%20ApoB100%2FApo,hypertension%20in%20the%20study%20groupExternal Link
  7. What is heart disease? [Internet]. CDC; 15 May 2023 [Accessed 16 Jan. 2024]. Available from: https://www.cdc.gov/heartdisease/about.htmExternal Link
  8. Cardiovascular Risk Factors and Markers. A literature review. Vasculopathies. 19 Jan. 2003. [Accessed 16 Jan. 2024]. Available from: https://link.springer.com/chapter/10.1007/978-3-319-89315-0_2External Link
  9. Thiriet M. Cardiovascular Risk Factors and Markers. Vasculopathies. 2019 Feb 19;8:91–198. [Accessed 16 Jan. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7123062/#:~:text=The%20major%20independent%20cardiovascular%20risk,HDLCS%20concentration%20%5B226%5D. External Link

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