Anti Phospholipid Antibody IgM

The Anti Phospholipid Antibody IgM test measures the levels of immunoglobulin M (IgM) antiphospholipid antibodies (aPL) in the blood. These antibodies are formed when the immune system mistakenly targets and attacks phospholipids (the essential component of cell membranes). Once formed, these antibodies can bind to phospholipids and other proteins, leading to the development of antiphospholipid syndrome (APS), which increases the likelihood of abnormal blood clotting, recurrent miscarriages, and other complications.

The Anti Phospholipid Antibody IgM test measures specific IgM antibodies that are associated with antiphospholipid syndrome (APS). Identifying these antibodies is crucial for diagnosing APS, especially in cases where symptoms are unusual or accompanied by other autoimmune diseases.

The Anti Phospholipid Antibody IgM test identifies and quantifies IgM antibodies targeted against phospholipids. This test is important for diagnosing antiphospholipid syndrome (APS), which can increase the risk of blood clots. This test is especially important for determining the cause of blood clots, low platelet counts, repeated miscarriages, early births, and high blood pressure during pregnancy (preeclampsia).

This test is often recommended for people who have had unexplained blood clots, multiple miscarriages, or other signs linked to APS, like strokes or repeated pregnancy losses. This test can help distinguish between primary APS (which happens on its own) and secondary APS (which occurs alongside another condition). It can also be used to monitor disease activity and see how well treatments are working in people with APS or other autoimmune diseases like lupus (SLE). Doctors may recommend this test for people with a history of blood clots or pregnancy complications to assess the risk of future clots and guide treatment, such as the use of blood thinners. Additionally, the test can help diagnose APS early, as the presence of IgM antibodies might show an ongoing or recent immune response.

For this test, a duly filled coagulation requisition form (Annexure - CR/05) is mandatory for sample collection. This form can be provided by the laboratory personnel (phlebotomist) before sample withdrawal. It is also recommended to discontinue heparin for a day and oral anticoagulants for 7 days before sample collection, or as advised by the doctor.

Lab test results may vary across different laboratories. Abnormal test results require an expert interpretation. Therefore, never try to self-medicate at home based solely on these results. Always consult a doctor for a proper understanding of the test results. The insights from this test help the doctor tailor an appropriate treatment plan.