Affiliates - LFT (Liver Function Test) near me in Haridwar

The Bilirubin (Total, Direct and Indirect) test measures the level of three forms of bilirubin such as total bilirubin, direct (conjugated bilirubin), and indirect (unconjugated) bilirubin in the blood. Total bilirubin represents the sum of direct and indirect bilirubin. Direct bilirubin is the water-soluble form of bilirubin that has been processed by the liver via a conjugation process with glucuronic acid and is ready to be excreted into the bile ducts and ultimately into the intestines. Indirect bilirubin is the water-insoluble form of bilirubin that has not yet been processed by the liver and is bound to albumin in the blood. It is formed in the spleen and liver during the breakdown of hemoglobin from old or damaged red blood cells and cannot be excreted directly by the liver. Instead, it is transported to the liver, where it undergoes conjugation to become direct bilirubin. 

Getting tested with the Bilirubin (Total, Direct and Indirect) test provides valuable information into various aspects of liver function, bile duct health, and the body’s ability to break down and eliminate bilirubin.

Gamma-Glutamyl Transferase (GGT) is an enzyme found in various organs, with the highest concentration in the liver. Usually, this enzyme is present in low levels in the blood. However, when there is liver damage or disease, GGT is released into the bloodstream, causing an increase in GGT levels. In addition to the liver, GGT can also be elevated in conditions affecting the bile ducts or the pancreas. It is usually, the first liver enzyme to rise in the blood when there is any damage or obstruction in the bile duct, making it one of the most sensitive liver enzyme tests for detecting bile duct problems.

An SGPT (Alanine Transaminase) test measures the level of alanine transaminase (ALT), also known as SGPT, in the blood. ALT is found predominantly in the liver and in smaller amounts in other tissues, including the kidneys, heart, and skeletal muscles. It is involved in amino-acid metabolism, particularly in the conversion of alanine and other metabolites during normal cellular processes.

Elevated ALT levels in the blood may indicate liver cell injury or inflammation. When liver cells are damaged, ALT can be released into the bloodstream, causing its level to increase. Therefore, the SGPT/ALT test is commonly used to assess possible liver injury and may be elevated in conditions such as hepatitis, fatty liver disease, cirrhosis, and other liver disorders. However, an elevated ALT level does not by itself establish a specific diagnosis or indicate the extent of liver damage.

An Alkaline Phosphatase (ALP) test measures the quantity of ALP enzyme present throughout the body. The main sources of this enzyme are the liver and bones. It exists in different forms depending on where it originates, such as liver ALP, bone ALP, and intestinal ALP. In the liver, it is found on the edges of the cells that join together to form bile ducts. 

ALP levels can be increased during pregnancy as it is found in the placenta of pregnant women. It is also higher in children because their bones are in the growth phase. ALP is often high during growth spurts (a short period when an individual experiences quick physical growth in height and body weight).

An SGOT (Aspartate Aminotransferase) test measures the level of serum glutamic-oxaloacetic transaminase (SGOT), also known as aspartate aminotransferase (AST), in the blood. AST is an enzyme involved in amino-acid metabolism and is found in several body tissues, particularly the liver, heart and skeletal muscles. When cells in these tissues are damaged, AST can be released into the bloodstream, causing its levels to rise. Therefore, this test helps detect possible tissue injury, including liver damage, and is often performed as part of a liver function test panel.

The Protein Total, Serum test measures the amount of proteins in the body. Proteins are known as the building blocks of all cells and tissues. They play a crucial role in the growth and development of most of your organs and in making enzymes and hormones. There are two types of proteins found in the body, namely albumin and globulin. About 60% of the total protein is made up of albumin, which is produced by the liver. It helps to carry small molecules such as hormones, minerals, and medicines throughout the body. It also serves as a source of amino acids for tissue metabolism. On the other hand, globulin is a group of proteins that are made by the liver and the immune system. They play an important role in liver functioning, blood clotting, and fighting off infections.