
17p (TP53) Deletion - FFPE near me in Mumbai







Mutations in the TP53 gene are associated with the deletion of chromosome 17. This is indicative of poor prognosis in Multiple Myeloma (MM) cases. Del 17p/TP53 alterations are the most important prognostic and predictive markers for treatment decisions in CLL. This test uses FISH (Fluorescence in situ hybridization) technology to detect 17p deletion. FISH is a technique to detect specific DNA sequences in your body cells. Screening for 17p deletion in Multiple Myeloma cases aids management decisions & directs these high-risk patients toward alternative therapies. This deletion has also been detected in Chronic Lymphocytic Leukemia (CLL) & is associated with poor prognosis.
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