
HLA B27 (Human Leukocyte Antigen B27) - PCR near me in Howrah










An HLA B27 (Human Leukocyte Antigen B27) - PCR test is a blood test that helps to identify the presence of Human Leukocyte Antigen B27(HLA B-27), a specific type of protein that is present on the surface of white blood cells (WBCs) that helps the body's immune system tell the difference between its own cells and foreign/harmful substances. This test is widely available with Tata 1mg labs at an affordable price in Howrah
Your doctor may suggest an HLA B-27 test if you experience signs and symptoms such as stiffness and chronic pain in the back, neck, or chest, inflammation in eyes, urethra, and joints, the appearance of skin lesions, recurring fever, abdominal pain, or digestive problems indicative of an autoimmune disorder. Additionally, this test is also used during an organ transplant to match donated tissue with a transplant recipient to minimize the risk of organ rejection and improve the success of the transplantation procedure. No special preparation is needed for this test. You may eat and drink as per your daily routine.








What does HLA B27 (Human Leukocyte Antigen B27) - PCR measure?
An HLA B27 (Human Leukocyte Antigen B27) - PCR test is used to determine the presence or absence of the HLA B27 antigen to rule out the possibility of an autoimmune disorder. This gene is found on the surface of certain white blood cells and may increase the risk of developing conditions like ankylosing spondylitis, reactive arthritis, and psoriatic arthritis.
A positive result means the gene is present, and there may be a higher risk of these conditions. A negative result means the gene is not found. However, it is important to know that not having the HLA B27 gene does not fully rule out autoimmune disorders, as some people without the gene can still develop them.





FAQs related to HLA B27 (Human Leukocyte Antigen B27) - PCR in Howrah
- Parameswaran P, Lucke M. HLA-B27 Syndromes. [Updated 2023 Jul 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from:
- Zochling J, Bohl-Bühler MH, Baraliakos X, Feldtkeller E, Braun J. Infection and work stress are potential triggers of ankylosing spondylitis. Clin Rheumatol. 2006 Sep;25(5):660-6.[Accessed 06 Nov. 2023]. Available from:
- HLA- B27 Antigen [Internet]. Rochester, NY: University of Rochester Medical Center; [Accessed 06 Nov. 2023]. Available from:
- N P, Shanmugam SG, Devi SS, Chinambedu Dandapani MP, S R, D'Cruze L. Detection of Human Leukocyte Antigen B27 by Flowcytometry in Patients With Suspected Ankylosing Spondylitis in a Tertiary Care Centre. Cureus. 2021 Feb 25;13(2):e13560. [Accessed 06 Nov. 2023]. Available from:
- McMichael A, Bowness P. HLA-B27: natural function and pathogenic role in spondyloarthritis. Arthritis Res. 2002;4 Suppl 3(Suppl 3):S153-8. [Accessed 06 Nov. 2023]. Available from:
- Ankylosing Spondylitis. [Internet]. NIH; May. 2023. [Accessed 06 Nov. 2023]. Available from:
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