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Hemoglobin (Hb) Electrophoresis by HPLC

750
4.1
NABL, ISO
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Overview
Interpreting Results

Overview of Hemoglobin (Hb) Electrophoresis by HPLC

What is Hemoglobin (Hb) Electrophoresis by HPLC?

This assay is useful in the diagnosis of disorders associated with abnormal forms of hemoglobin like sickle cell anemia, thalassemia.

Why is Hemoglobin (Hb) Electrophoresis by HPLC done?

  1. If you have signs or symptoms of hemolytic anemia like jaundice, fatigue, pale skin or splenomegaly 
  2. If your complete blood count and peripheral smear indicate that you may have an abnormal form of hemoglobin 
  3. It is commonly done as a part of newborn screening 
  4. It may used for prenatal screening if a parent is at high risk 

Preparation for Hemoglobin (Hb) Electrophoresis by HPLC

  • No special preparation required

Sample Type for Hemoglobin (Hb) Electrophoresis by HPLC

The sample type collected for Hemoglobin (Hb) Electrophoresis by HPLC is: Blood

Interpreting Hemoglobin (Hb) Electrophoresis by HPLC results

Interpretations

         All the results should be carefully interpreted in correlation with the patient's signs and symptoms and other laboratory findings. 

  • Presence of high level of sickle cell hemoglobin (HbS ) on HPLC denotes either sickle cell trait or sickle cell anemia 
  • Increased levels of fetal hemoglobin (HbF) on HPLC is associated with beta thalassemia major. Sometimes, it can also be seen in sickle cell anemia 
  • High HbA2 levels are mostly associated with beta thalassemia minor or trait. Recent studies say that HbA2 level between 4 to 9% is diagnostic of beta thalassemia trait 
  • Other less common hemoglobins which can be detected are hemoglobin D, J, G, M etc.

Provided By

NABL

ISO

About R B Diagnostics

RB is your one-stop medical solution provider. We are an NABL accredited pathology with a state-of-the-art radiology setup including MRI and CT Scan unit. We also have polyclinics, pharmacy, physiotherapy units, fertility clinic and diabetic clinic under our umbrella. We have partnered with Roche and BioRAD to provide 100% computerized pathology with error-free setup. Our MRI imaging and CT scan setup provides highest level of service to our patients in a relaxed, caring, and supportive environment. We are one of the only diagnostic imaging centers in PAN INDIA to use such high quality equipment at such affordable costs. And, unlike open or standing MRI devices, our imaging technology provides first-time high quality image results which requires no second opinion. RB Diagnostics have earned a strong and loyal physician referral base in this miraculously small time line. The real credit goes to our specialized staff and a dedicated management. Physicians rely on us for flexible scheduling, ultra-high quality imaging, and rapid diagnostic response by our specialty radiologists. Our staff of nationally recognized, board certified radiologists give you and your physician the confidence that only highly-trained medical professionals are reviewing your medical reports. From our caring and competent staff to our warm and inviting setting, the primary concern of our staff is always patient comfort and convenience. The MRI Center offers evening, weekend, and same-day appointments. Situated at heart of Lake Town with 50+ employees, we are ready to serve the community with next generation diagnosis. The center is designed keeping in mind the comfort of the patients. Our equipments are backed by industry experts who are committed to provide the top most possible quality blended with incomparable service.

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