IGF Binding Protein-3
What is IGF Binding Protein-3?
Insulin-like growth factor binding protein 3 (IGFBP-3) is the transporter of Insulin like growth factor-1 (IGF-1). The level of IGFBP-3 & IGF-1 in the blood is controlled by pituitary hormone & hence can be used to detect pituitary gland diorders.Pituitary gland secretes growth hormone hence symptoms such as such as short stature or excessive growth (gigantism) may warrant an IGFBP-3 test may require IGFBP3 test. The test is also used to check progress of treatment of growth hormone disorders.
Why is IGF Binding Protein-3 done?
- To diagnose disorders of growth due to under or over secretion of Growth Hormone in children and adults
- To check the efficacy of treatment of growth disorders using recombinant human growth hormone
- As a possible adjunct to insulin-like growth factor 1 and growth hormone in the diagnosis and follow-up of acromegaly and gigantism