53 people

bought recently

Melapik Plus Cream

Hydroquinone (2% w/w)+ Tretinoin (0.025% w/w)+ Fluocinolone acetonide (0.01% w/w)

Genuine

Authenticity Assured

Prescription

required

Melapik Plus Cream is a medicine that contains a combination of medicines that is used to treat melasma. It helps in quick skin renewal. It provides relief from redness, swelling, and itching.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 09 Feb 2026 | 07:03 PM (IST)

₹183

₹210.9

13% off

Get for

₹156

on orders above ₹1200

Use Code 1MGNEWPLUS

Get for

₹168

on orders above ₹300

Use Code 1MGNEW

1/2

Welcome Gift | For First Order

15% EXTRA OFF

20 gm Cream

Get by 3pm, Tomorrow

Gurgaon

Save more with additional offers

Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*

Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20

Earn cashback up to Rs. 100 with Amazon Pay Later

Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*

Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20

Earn cashback up to Rs. 100 with Amazon Pay Later

Get cashback up to ₹500

Get upto Rs.500 Cashback on minimum transaction of Rs.999/- with Mobikwik Wallet.

Get upto Rs.150 Cashback

General Information

Contains

Hydroquinone (2% w/w)+ Tretinoin (0.025% w/w)+ Fluocinolone acetonide (0.01% w/w)

Marketer

KLM Laboratories Pvt Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

Melapik Plus Cream should be used in the dose and duration as advised by your doctor. Wash your hands before using this medicine. It is advised to check the label for directions before use. Do not use this medicine more than the recommended dose. Inform your doctor if you have known allergies to this medicine.

Common side effects of this medicine include burning, irritation, itching, and redness at the site of application. It may also cause dry skin, acne, and itching. If any of these side effects bother you or get worse, consult your doctor.

Inform your doctor if you are pregnant or are suffering from any other disease. Caution is needed while breastfeeding; this medicine is not recommended unless advised by your doctor. Do not use this medicine if you have a history of allergic reactions to any of the ingredients in this product.

Uses of Melapik Plus Cream

Melasma

Side effects of Melapik Plus Cream

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Melapik Plus

Burning sensation
Dryness
Erythema (skin redness)
Itching
Skin peeling
Dry skin
Acne

How to use Melapik Plus Cream

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

How Melapik Plus Cream works

Melapik Plus Cream is a combination of three medicines: Hydroquinone, Tretinoin and Fluocinolone acetonide which treat melasma (dark spots on skin). The exact way this triple combination improves melasma is not fully known. Hydroquinone helps reduce melanin (skin pigment), tretinoin promotes skin cell turnover, and fluocinolone acetonide reduces skin inflammation.

All substitutes for Melapik Plus Cream

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Along with applying Melapik Plus Cream, wear long-sleeved clothing, sunglasses, or a hat whenever you step outside in the hot sun for better protection.
Do not cover the area being treated with airtight dressings unless instructed by a doctor.
Use moisturizer regularly to overcome skin dryness during the course of treatment.
You may also use certain safe cosmetics (after consulting with your doctor) to lighten pigmentation.
Before using Melapik Plus Cream, inform your doctor if you have any skin problems or are applying any other medicines to your skin.

Safety advice

Alcohol

No interaction found/established

Pregnancy

UNSAFE

Melapik Plus Cream is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

SAFE IF PRESCRIBED

Melapik Plus Cream may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving

No interaction found/established

Kidney

No interaction found/established

Liver

No interaction found/established

Frequently asked questions

What is Melapik Plus Cream used for?

Melapik Plus Cream is prescribed for the short-term treatment of moderate to severe melasma, a dark, patchy discoloration on the face. It helps lighten those spots when used along with sun protection, avoiding sunlight.

Can Melapik Plus Cream be used for other dark spots or skin lightening?

No. Melapik Plus Cream is only approved for facial melasma. It has not been proven safe or effective for other pigment problems like freckles, age spots, or acne marks.

Is Melapik Plus Cream meant for long-term use?

No. Melapik Plus Cream is for short-term use only. Once your dark patches improve, your doctor may suggest stopping and switching to other maintenance options. Using it continuously may increase the risk of skin side effects.

What precautions should I take while using Melapik Plus Cream?

While you are on Melapik Plus Cream therapy, you should avoid direct sunlight exposure, UV lamps, always apply sunscreen (SPF 30 or higher), wear protective clothing, do not use on broken or irritated skin, avoid using harsh soaps, astringents, products that cause dryness, or peeling.

Can Melapik Plus Cream cause allergic reactions?

Melapik Plus Cream may rarely trigger serious allergic or asthma-like reactions in sensitive people. If you experience swelling, wheezing, or severe itching, stop using it and get medical help immediately.

What is “exogenous ochronosis” and why is it important to know for people using Melapik Plus Cream?

Exogenous ochronosis is a blue-black darkening of the skin that can happen with long-term use of hydroquinone (present in Melapik Plus Cream). It is rare but may be permanent. If your skin starts getting darker instead of lighter, stop using the medicine and contact your doctor.

Can Melapik Plus Cream thin my skin or affect hormones?

Yes, with prolonged or excessive use, the corticosteroid (fluocinolone) present in Melapik Plus Cream can cause skin thinning or, in rare cases, hormonal (adrenal) effects. Use it exactly as directed, usually once daily, only for a short time.

Are there any serious side effects of Melapik Plus Cream?

Serious side effects of Melapik Plus Cream may include severe burning, swelling, blistering of the skin, worsening pigmentation, signs of infection, skin thinning, and any allergic reaction (rash, difficulty breathing, facial swelling). Seek immediate medical attention if you notice any symptoms.

Can people with darker skin tones use Melapik Plus Cream safely?

Melapik Plus Cream has not been well-studied in very dark skin types (Fitzpatrick V-VI). Over-bleaching, uneven lightening may occur. Your dermatologist can guide you on whether it is appropriate.

What happens if I stop using Melapik Plus Cream after improvement?

Melasma often comes back after stopping Melapik Plus Cream. To maintain results, continue sun protection, and follow your doctor’s advice on safer long-term maintenance options.

Fact Box

Habit Forming

Therapeutic Class

DERMA

References

Fluocinolone acetonide, hydroquinone, and tretinoin [Prescribing Information]. Canada: G Production Inc.; 2014. [Accessed 29 Apr. 2019] (online) Available from:
Fluocinolone acetonide + hydroquinone + tretinoin [Prescribing Information]. Canada: G Production Inc.; 2013. [Accessed 29 Apr. 2019] (online) Available from:
CiplaMed. Fluocinolone acetonide + Hydroquinone + Tretinoin [Prescribing Information]. [Accessed 14 Aug. 2024] (online) Available from:
Fluocinolone acetonide, hydroquinone, tretinoin [Prescribing Information]. Dallas, TX: Galderma Laboratories, LP; 2023.

User feedback

Patients taking Melapik Plus Cream

Once A Day

86%

Twice A Day

Alternate Day

Twice A Week

Once A Week

Thrice A Day

What are you using Melapik Plus Cream for?

Melasma

68%

Others

20%

Skin disorders

Acne

Hyperpigmentation

How much was the improvement?

Average

43%

Poor

35%

Excellent

22%

What were the side-effects while using Melapik Plus Cream?

Application site reactions (burning, irritation, itching and redness)

90%

No Side Effect

10%

How do you take Melapik Plus Cream?

With or without food

53%

With food

33%

Empty stomach

13%

Please rate Melapik Plus Cream on price

Average

48%

Expensive

27%

Not Expensive

24%

Want to know more

We provide you with authentic, trustworthy and relevant information

Have issue with the content

Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: KLM Laboratories Pvt Ltd
Address: 1004, Hubtown Viva, Jogeshwari (E), Mumbai-400060, Maharashtra, India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Melapik Plus Cream. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Melapik Plus Cream

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Melapik Plus Cream

Side effects of Melapik Plus Cream

How to use Melapik Plus Cream

How Melapik Plus Cream works

All substitutes for Melapik Plus Cream

Clearz Max Cream

Cutilite Cream

GLomela Cream

I Glow Night Cream

Seraglow Cream

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Melapik Plus Cream used for?

Can Melapik Plus Cream be used for other dark spots or skin lightening?

Is Melapik Plus Cream meant for long-term use?

What precautions should I take while using Melapik Plus Cream?

Can Melapik Plus Cream cause allergic reactions?

What is “exogenous ochronosis” and why is it important to know for people using Melapik Plus Cream?

Can Melapik Plus Cream thin my skin or affect hormones?

Are there any serious side effects of Melapik Plus Cream?

Can people with darker skin tones use Melapik Plus Cream safely?

What happens if I stop using Melapik Plus Cream after improvement?

Fact Box

Habit Forming

Therapeutic Class

References

User feedback

Patients taking Melapik Plus Cream

What are you using Melapik Plus Cream for?

How much was the improvement?

What were the side-effects while using Melapik Plus Cream?

How do you take Melapik Plus Cream?

Please rate Melapik Plus Cream on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests