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MRP: Rs. 27.62 for 1 tube(s) (5 GM cream each)
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Composition for ZOTADERM


food interaction for ZOTADERM

alcohol interaction for ZOTADERM

pregnancy interaction for ZOTADERM

lactation interaction for ZOTADERM

There is no data available. Please consult doctor before consuming the drug.
Interaction with alcohol is unknown. Please consult your doctor.
Zotaderm cream may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.




Betamethasone is used to treat allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, and bronchial asthma Topical preparations of betamethasone are used to treat skin problems like eczema (a type of itchy skin rash), atopic dermatitis (inflammation of skin) and psoriasis of the scalp, hands and feet.

How it works

Betamethasone belongs to a group of medicines called corticosteroids which have anti-inflammatory and immune system suppressing activity. It prevents late phase allergic reactions by decreasing the chemicals responsible for the allergy.

Common side effects

Acne-like rash, Allergic reaction, Skin infection, Shortness of breath, Difficulty in swalloing, Wheezing, Burning sensation, Changes in skin color, Itching, Skin cracking, Dry skin


Clotrimazole is used for the treatment of fungal skin infections mainly infections of the vagina, vulva, groin or penis along with ringworm, fungal nappy rash and infections of the armpit, toes and skin folds. 

How it works

Clotrimazole acts against the fungi by impairing the permeability of the fungal cell wall and inhibits the activity of enzymes within the cell. It specifically inhibits the biosynthesis of ergosterol and other sterols required for cell membrane production.

Common side effects

Application site reaction, Application site irritation, Burning sensation, Fever, Itching, Skin redness, Stomach pain, Stomach upset, Vaginal discharge, Vomiting


Oral neomycin is used before the operation of the gut to kill the bacteria which normally live in the gut that may cause a serious infection and in treatment of patients with coma due to liver disease (hepatic coma). 

How it works

Neomycin is an antibiotic belonging to the class of aminoglycoside. Neomycin prevents the bacterial growth by stopping the production of essential protein in the bacterial cells.

Common side effects

Uncoordinated body movements, Itching, Eye irritation, Increased saliva production, Nausea, Renal injury, Increased sensitivity to light, Eye pain, Diarrhoea, Allergic reaction, Tingling sensation, Eye surface inflammation, Vomiting, Abnormal blood cell, Drooping eyelids, Altered pupil size, Increased bilirubin in the blood, Pain, Skin redness, Numbness, Disorientation (alteration of mental status), Increased production of tears, Abnormal eye sensation, Increased intraocular pressure, Liver enzyme increased, Fever, Ear damage, Blurred vision, Mouth ulcer, Premature destruction of red blood cells, Allergy, Confusion, Thinning of eyes, Swelling


No substitutes found

Expert advice for ZOTADERM

  • Take betamethasone tablet by mouth with food or milk to prevent stomach upset. 
  • Do not take betamethasone tablets If you are allergic to betamethasone or any of the other ingredients of the tablet.
  • Do not take betamethasone tablets If you have an infection and have not yet started taking medicine (e.g. antibiotics) to treat it.
  • Do not use betamethasone cream if you are allergic to betamethasone or any of the other ingredients in this medicine.
  • Do not use the cream on your face repetitively for more than 5 days.
  • Do not use a large amount of cream continuously on large areas of the body since it can affect your hormones.
  • Excessive usage of cream in children might affect their growth and development.
  • Don’t apply the cream near your eyes.
  • Don’t swallow the cream, it is not meant for internal use.
  • Don’t use the cream under plaster or bandage.

Frequently asked questions for ZOTADERM


Q. Are betnesol, stemin, stemin forte, betamil, and betamine same drugs?
Yes, these are all brand names of betamethasone drug belonging to a class of corticosteroids. However, their quantity might vary depending on the brand or formulation. Always seek doctor’s advice with regards to dosage and duration of the drug.
Q. Is betamethasone, betnesol, betnesol forte a steroid/ antibiotic?
Yes, betamethasone, betnesol and betnesol forte belongs to a class of drugs called corticosteroids. It is not an antibiotic.
Q. Is betamethasone cream available as over the counter (OTC) product?
Betamethasone cream is not available as OTC product.
Q. Is betnesol or betnesol injection safe?
Betnesol or betnesol injection is safe if used at prescribed doses and at prescribed duration as advised by your doctor.
Q. Does betamethasone cause hair loss or weight gain?
Betamethasone is not known to cause hair loss. On the contrary, it may cause weight gain and body hair growth (especially in females) on chronic persistent use of the product.
Q. Does betamethasone lighten skin/ bleach skin?
Betamethasone may cause skin pigmentation in few patients. It may lighten or darken the skin color. Do not use betamethasone without doctor’s advice.
Q. Is betamethasone valerate used for acne/ ringworm?
No. Betamethasone valerate can be used in conditions like eczema (a type of itchy skin rash), atopic dermatitis (inflammation of skin) and psoriasis of the scalp, hands and feet.
Q. Can I take ibuprofen with betamethasone?
Betamethasone when used in combination with non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, diclofenac, naproxen, there may be an increased risk of stomach ulceration and bleeding. Always follow doctor’s advice regarding its use.

Q. Does betnesol work in retention edema?
No. Betnesol (i.e. betamethasone) cannot be used in retention edema. On the contrary, it causes the fluid and salt retention thereby adding to the edema problem.
Q. Is betamethasone stronger than hydrocortisone?
Betamethasone and hydrocortisone belong to the same class of medications (i.e. corticosteroids) and produce almost similar pharmacological responses. The effect may vary based on the conditions and individual response. Always follow doctor’s advice regarding its use.


Q. Is clotrimazole a steroid/ used for thrush/ good for ringworm/ good for toenail fungus?
Clotrimazole is an antifungal medication and not a steroid. It is used for treating thrush, ringworm. It may be used for toenail fungus; however its efficacy in this case is not completely established. Patients should follow the advice of the doctor regarding its use.
Q. Is clotrimazole available over the counter?
Yes, clotrimazole cream is available over the counter. But if this is the first time you have had vaginal itching and discomfort, talk with a physician before using clotrimazole.
Q. Is clotrimazole better than miconazole?
Although clotrimazole and miconazole are different drugs, they work in similar ways. Both are used for treatment of fungal infection, primarily yeast. Despite these similarities, they are often used in different parts of the body and they have different active ingredients and so cannot be compared. Both medications work well, but one of them may work better for some people than others. Check with your doctor for more details.
Q. Is candida a steroid/ curable/ contagious/ a STD/ dangerous/ curable/ a steroid cream/ infection dangerous?
Candida is a yeast, a form of fungus. It causes infections such as candidiasis or thrush in humans and other animals. Individuals with Candida infections are not usually contagious, though in some settings immunocompromised people can catch the infection. The infection does not usually spread by sexual contact. Candida infection is curable but if not treated early it can result in a serious infection.
 Q. Is canesten hydrocortisone for thrush?
Canesten HC cream contains two active ingredients, clotrimazole (antifungal medicine used to treat infections with fungi and yeasts) and hydrocortisone (corticosteroid medicine that is applied to the skin to relieve the symptoms of inflammation). It is used to treat vaginal thrush.


Q. Does neomycin has sulfa or does the sulphate present in this drug contain sulfa?
No, neomycin does not contain sulfa (sulphonamide group) and the sulphate group present in this drug has no link with sulfa either.
Q. Does neomycin expire?
Yes. The expiry date is provided on the blister pack of tablets or the ointment tube.
Q. Does neomycin cover pseudomonas?
No, neomycin is not effective against pseudomonas 
Q. Does neomycin contain penicillin?
No, neomycin does not contain penicillin. It belongs to a group of drugs called aminoglycosides.
Q. Does neosporin help acne /cold sores
Neosporin contains neomycin in addition to bacitracin and polymyxin. Neosporin does not treat acne  or cold sores. It only helps in the treatment of some infections of the skin.
Q. Does neosporin help scars?
Neosporin contains neomycin in addition to bacitracin and polymyxin. Neosporin does not help in the treatment of scars. It only helps in the treatment of some infections of the skin.
Q. Does neosporin help cuts?
Neosporin contains neomycin in addition to bacitracin and polymyxin. Neosporin only helps prevent or treat the infection of wounds. It does help heal the cuts.
Q. Does neomycin cause tinnitus?
Neomycin is known to cause damage to the ear. One of the symptoms of damage to ear is tinnitus.
Q. Is neomycin safe?
Neomycin is safe if used at prescribed doses for the prescribed duration as advised by your doctor.


Content on this page was last updated on 15 July, 2014, by Dr. Varun Gupta (MD Pharmacology)