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Zodifen PLUS 100mg/325mg Tablet

Aceclofenac (100mg)+ Paracetamol (325mg)

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Zodifen PLUS 100mg/325mg Tablet is a pain-relieving medicine. It reduces pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It may also relieve muscle pain, back pain, toothache, or pain in the ear and throat.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 13 Nov 2026 | 01:02 AM (IST)

₹49.5 MRP ₹56.2512% off

(Inclusive of applicable taxes)

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Zodifen PLUS 100mg/325mg Tablet is currently sold out

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Acemiz Plus Tablet

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Zodifen PLUS 100mg/325mg Tablet

strip of 10 tablets

₹49.5

~~₹56.25~~

Same composition

Acemiz Plus Tablet

strip of 10 tablets

Aceclofenac (100mg) + Paracetamol (325mg)

by Lupin Ltd

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Flat ₹50 cashback. T&C Apply*

Get upto Rs.150 Cashback on minimum transaction of Rs.599/- with Mobikwik UPI (@ikwik).

Get up to ₹150 cashback on a minimum order value (MOV) of ₹499 and above, valid once per customer.

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General Information

Contains

Aceclofenac (100mg)+ Paracetamol (325mg)

Marketer

Choroid Laboratories

Storage

Store below 30°C

The content is shown in English

Product introduction

Zodifen PLUS 100mg/325mg Tablet should be taken with or without food. It should be taken regularly as advised by your doctor. Your doctor may change the dose and time between doses according to your pain level and needs. Do not take more or use it for a longer duration than recommended by your doctor.

Some of the common side effects of this medicine include nausea, dizziness, and diarrhea. You should let your doctor know if any of these side effects bother you or if they do not go away with time. Your doctor may help you with ways to reduce or prevent these side effects by prescribing an alternative medicine or adjusting the dose.

Zodifen PLUS 100mg/325mg Tablet may not be suitable for everyone. Before taking it, let your doctor know if you have any problems with your heart, kidneys, or liver, or if you have stomach ulcers. Also, tell your doctor about all the other medicines you take to ensure they are safe. Pregnant and breastfeeding mothers should consult their doctors before using Zodifen PLUS 100mg/325mg Tablet.

Uses of Zodifen PLUS Tablet

Pain relief : Zodifen PLUS 100mg/325mg Tablet helps relieve pain in conditions such as headache, body ache, muscle pain, toothache, menstrual cramps, and minor injuries.

Benefits of Zodifen PLUS Tablet

Pain relief
Zodifen PLUS 100mg/325mg Tablet is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. Some of the conditions in which Zodifen PLUS 100mg/325mg Tablet is used are rheumatoid arthritis, osteoarthritis, muscle pain, back pain, toothache, or pain in the ear and throat.

Side effects of Zodifen PLUS Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zodifen PLUS

Indigestion
Abdominal pain

How to use Zodifen PLUS Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zodifen PLUS 100mg/325mg Tablet may be taken with or without food.

How Zodifen PLUS Tablet works

Zodifen PLUS 100mg/325mg Tablet is a combination of two medicines: Aceclofenac and Paracetamol. These medicines work by blocking the action of chemical messengers responsible for pain, fever and inflammation (redness and swelling).

All substitutes for Zodifen PLUS 100mg/325mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Take Zodifen PLUS 100mg/325mg Tablet with food to reduce the risk of stomach irritation.
Do not take Zodifen PLUS 100mg/325mg Tablet with other medicines containing paracetamol without consulting your doctor.
Avoid taking Zodifen PLUS 100mg/325mg Tablet with other NSAIDs (such as ibuprofen or diclofenac) unless advised by your doctor.
Zodifen PLUS 100mg/325mg Tablet may cause dizziness or sleepiness, so avoid driving or operating machinery until you know how it affects you.
Stop taking Zodifen PLUS 100mg/325mg Tablet and seek medical attention if you develop severe stomach pain or black/tarry stools.
Stay well hydrated while using Zodifen PLUS 100mg/325mg Tablet, as dehydration may increase the risk of kidney-related side effects.
Inform your doctor if you have a history of stomach ulcers, kidney disease, or liver disease before taking Zodifen PLUS 100mg/325mg Tablet.
Do not increase the dose or frequency of Zodifen PLUS 100mg/325mg Tablet without medical advice.
Inform your doctor if you develop a rash, swelling, or signs of an allergic reaction while taking Zodifen PLUS 100mg/325mg Tablet.
If dizziness occurs after taking Zodifen PLUS 100mg/325mg Tablet, avoid activities requiring alertness such as driving.
If pain persists or keeps recurring despite taking Zodifen PLUS 100mg/325mg Tablet, consult your doctor for further evaluation.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Zodifen PLUS 100mg/325mg Tablet. Please consult your doctor.

Pregnancy

UNSAFE

Zodifen PLUS 100mg/325mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Zodifen PLUS 100mg/325mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Zodifen PLUS 100mg/325mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Zodifen PLUS 100mg/325mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Zodifen PLUS 100mg/325mg Tablet is not recommended in patients with severe kidney disease.

Liver

UNSAFE

Zodifen PLUS 100mg/325mg Tablet is unsafe to use in patients with liver disease and should be avoided.
However, the use of Zodifen PLUS 100mg/325mg Tablet is not recommended in patients with severe liver disease and active liver disease.

Frequently asked questions

What is Zodifen PLUS 100mg/325mg Tablet and what is it used for?

Zodifen PLUS 100mg/325mg Tablet is a medicine that contains aceclofenac and paracetamol. It is used to relieve pain, swelling, and inflammation in conditions such as arthritis, joint pain, back pain, muscle pain, dental pain, and pain caused by injuries. It works by reducing certain chemicals in the body that cause pain and inflammation. While Zodifen PLUS 100mg/325mg Tablet helps control pain and discomfort, it does not treat the underlying cause of the condition. It should only be taken as prescribed by your doctor.

Can I stop taking Zodifen PLUS 100mg/325mg Tablet when my pain is relieved?

If Zodifen PLUS 100mg/325mg Tablet is prescribed for short-term pain, it can usually be stopped once your symptoms improve. However, if you are taking it for a condition that causes long-term pain, such as arthritis, your doctor may advise continuing it for a specific period. Always follow your doctor’s instructions before stopping the medicine.

What are the side effects of Zodifen PLUS 100mg/325mg Tablet?

Zodifen PLUS 100mg/325mg Tablet may cause side effects such as nausea, vomiting, stomach pain, heartburn, or dizziness in some people. These symptoms are more likely if the medicine is taken on an empty stomach. In some cases, it may also increase blood pressure or cause fluid retention, especially with repeated use. Rare but serious warning signs include black stools, vomiting blood, or severe stomach pain, which may indicate stomach bleeding. Contact your doctor if side effects persist or become severe.

Who should not take Zodifen PLUS 100mg/325mg Tablet?

Zodifen PLUS 100mg/325mg Tablet should not be taken by people who are allergic to this medicine or to other similar pain relievers known as NSAIDs. It is also not recommended for people with stomach ulcers, active stomach bleeding, severe liver or kidney disease, uncontrolled high blood pressure, or heart failure unless advised by a doctor. It is generally avoided during pregnancy, particularly in the later stages. Always inform your doctor about your medical history before taking Zodifen PLUS 100mg/325mg Tablet.

How quickly does Zodifen PLUS 100mg/325mg Tablet work?

Zodifen PLUS 100mg/325mg Tablet may start reducing pain within a few hours in many people, although the exact timing can vary. The aceclofenac component helps reduce inflammation, while paracetamol helps relieve pain and fever. If you need to take the medicine for several days or if the pain does not improve, the underlying cause may need medical evaluation. If symptoms worsen or persist, consult your doctor.

Is Zodifen PLUS 100mg/325mg Tablet the same as tramadol?

No, Zodifen PLUS 100mg/325mg Tablet is not the same as tramadol. Zodifen PLUS 100mg/325mg Tablet contains an anti-inflammatory medicine and paracetamol, which help reduce pain and inflammation. Tramadol works differently by affecting pain signals in the brain. It also has a higher risk of drowsiness and dependence. Because these medicines work differently and have different side effects, they should not be confused. If you are unsure about your prescription, consult your doctor.

Can I take two doses of Zodifen PLUS 100mg/325mg Tablet in a day?

You should not change the dose or frequency of Zodifen PLUS 100mg/325mg Tablet on your own. Taking it more often than prescribed increases the risk of stomach bleeding, kidney damage, and liver damage. The risk of paracetamol overdose is higher if you also take other medicines that contain paracetamol. Always follow the dose recommended by your doctor.

What are the early signs of kidney problems while taking Zodifen PLUS 100mg/325mg Tablet?

Early signs of possible kidney problems may include reduced urination, swelling of the feet or face, unusual tiredness, nausea, or rising blood pressure. Although these symptoms can have many causes, they should not be ignored. Anti-inflammatory medicines like aceclofenac may affect kidney function, especially in people who are dehydrated or already have kidney problems. If you notice these symptoms, stop self-medicating and consult your doctor promptly.

Fact Box

Habit Forming

Therapeutic Class

PAIN ANALGESICS

References

Furst DE, Ulrich RW, Prakash S, et al. Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ (Editors). Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 621-642.
Grosser T, Smyth EM, FitzGerald GA. Pharmacotherapy of Inflammation, Fever, Pain, and Gout. In: Brunton LL, Hilal-Dandan R, Knollmann BC (Editors). Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 13th ed. New York, NY: McGraw-Hill Education; 2018. pp. 685-709.
Eraas International. Aceclofenac+Paracetamol [Product Information]. [Accessed 14 Aug. 2024] (online) Available from:
Aceclofenac And Paracetamol. Zuventus; [Accessed 14 Aug. 2024] (online). Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Choroid Laboratories
Address: Surya Nagar Market, Vikhroli (West), Mumbai, Maharashtra, INDIA

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Home

Pain Analgesics

Anti Rheumatics Non Steroidal Systemic

Zodifen PLUS 100mg/325mg Tablet

Zodifen PLUS 100mg/325mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Zodifen PLUS Tablet

Benefits of Zodifen PLUS Tablet

Side effects of Zodifen PLUS Tablet

How to use Zodifen PLUS Tablet

How Zodifen PLUS Tablet works

All substitutes for Zodifen PLUS 100mg/325mg Tablet

acimol 100mg/325mg Tablet

Movexx Plus Tablet

alcinac P 100mg/325mg Tablet

Acenext P 100mg/325mg Tablet

Aldigesic P 100mg/325mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Zodifen PLUS 100mg/325mg Tablet and what is it used for?

Can I stop taking Zodifen PLUS 100mg/325mg Tablet when my pain is relieved?

What are the side effects of Zodifen PLUS 100mg/325mg Tablet?

Who should not take Zodifen PLUS 100mg/325mg Tablet?

How quickly does Zodifen PLUS 100mg/325mg Tablet work?

Is Zodifen PLUS 100mg/325mg Tablet the same as tramadol?

Can I take two doses of Zodifen PLUS 100mg/325mg Tablet in a day?

What are the early signs of kidney problems while taking Zodifen PLUS 100mg/325mg Tablet?

Fact Box

Habit Forming

Therapeutic Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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