Zix-RP Capsule

Aceclofenac (100mg)+ Paracetamol (325mg)+ Rabeprazole (10mg)

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Zix-RP Capsule is a pain-relieving medicine. It is used to treat pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It may also be used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 23 Jul 2026 | 01:06 AM (IST)

₹70.5 MRP ₹76.648% off

Gurgaon

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General Information

Contains

Aceclofenac (100mg)+ Paracetamol (325mg)+ Rabeprazole (10mg)

Marketer

Jenburkt Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Zix-RP Capsule also prevents and reduces the chances of acid reflux, heartburn, and stomach ulcers. This medicine can be taken with or without food. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.

This medicine's most common side effects include nausea, diarrhea, constipation, stomach pain, flatulence, and loss of appetite. If any of these side effects do not resolve with time or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing them.

Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any problems with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking to make sure they are safe.

Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness.

Uses of Zix-RP Capsule

Pain relief

Benefits of Zix-RP Capsule

Pain relief
Zix-RP Capsule is a combination medicine used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis. But, this pain-relieving action may damage the inner lining of the stomach. Therefore, this medicine also has an active ingredient called Rabeprazole, which reduces the acid secretion in our stomach, thereby reducing the damage caused by the painkillers.

Take it as it is prescribed to get the most benefit. Do not take more or longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Zix-RP Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zix-RP

Nausea
Diarrhea
Constipation
Stomach pain
Flatulence
Loss of appetite
Weakness
Flu-like symptoms

How to use Zix-RP Capsule

Take this medicine in the dose and duration as advised by your doctor. Zix-RP Capsule may be taken with or without food.

How Zix-RP Capsule works

Zix-RP Capsule is a combination of two pain relievers (Aceclofenac, Paracetamol) and a proton pump inhibitor (Rabeprazole). The pain relievers work by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). However, they may cause damage to the stomach lining. The proton-pump inhibitor is added to reduce acid secretion and prevent this damage.

Quick tips

Zix-RP Capsule should be taken with food to avoid getting an upset stomach
It may cause dizziness and sleepiness. Don't drive or do anything that requires mental focus until you know how it affects you.
Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness and increase the risk of liver damage.
Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first.
Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for a long duration.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Zix-RP Capsule.

Pregnancy

CONSULT YOUR DOCTOR

Zix-RP Capsule is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CAUTION

Zix-RP Capsule should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

UNSAFE

Zix-RP Capsule may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Zix-RP Capsule should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Zix-RP Capsule is not recommended in patients with severe kidney disease.

Liver

UNSAFE

Zix-RP Capsule is unsafe to use in patients with liver disease and should be avoided.
However, the use of Zix-RP Capsule is not recommended in patients with severe liver disease and active liver disease.

Frequently asked questions

What is Zix-RP Capsule?

Zix-RP Capsule is a combination of three medicines: Aceclofenac, Paracetamol and Rabeprazole. This medication helps in relieving pain and inflammation. Aceclofenac and Paracetamol work by lowering the levels of those chemical substances in the body which cause pain and inflammation. Rabeprazole helps in preventing the digestive problem that may occur due to Aceclofenac.

Can I stop taking Zix-RP Capsule when my pain is relieved?

Zix-RP Capsule, when used for long-term pain relief, should be continued for as long as advised by your doctor. It can be discontinued if you are using it for short-term pain relief.

Can the use of Zix-RP Capsule cause nausea and vomiting?

Yes, the use of Zix-RP Capsule can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small and frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to a doctor.

Can the use of Zix-RP Capsule cause dizziness?

Yes, the use of Zix-RP Capsule can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded it is better to rest for some time and resume once you feel better.

Can the use of Zix-RP Capsule cause damage to kidneys?

Yes, the long-term use of Zix-RP Capsule can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protects them from damage. Use of painkillers lowers the levels of prostaglandins in the body leading to kidney damage on long-term use. Use of painkillers is not recommended to patients with underlying kidney disease.

Can I take a higher than the recommended dose of this medicine?

No, taking a higher than the recommended dose of Zix-RP Capsule can increase the risks of side effects like nausea, vomiting, heartburn, indigestion, diarrhea and can also damage your kidneys on long-term use. If you are experiencing increased severity of pain or the pain is not relieved by the recommended doses of this medicine, please consult your doctor for re-evaluation.

What is the recommended storage condition for Zix-RP Capsule?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Fact Box

Habit Forming

Therapeutic Class

PAIN ANALGESICS

References

Zeelab Pharmacy: Aceclofenac + Paracetamol + Rabeprazole [Prescribing Information]. [Accessed 24 Nov. 2025]. Available from:

User feedback

Patients taking Zix-RP Capsule

Twice A Day

65%

Once A Day

34%

Thrice A Day

What are you using Zix-RP Capsule for?

Pain relief

60%

Others

30%

Dental pain

10%

How much was the improvement?

Poor

56%

Excellent

33%

Average

11%

What were the side-effects while using Zix-RP Capsule?

No Side Effect

100%

How do you take Zix-RP Capsule?

With food

100%

Please rate Zix-RP Capsule on price

Average

100%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Jenburkt Pharmaceuticals Ltd
Address: Nirmala Apartments,93, Jayprakash Road, Andheri (West),Mumbai - 400 058. India.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Home

Pain Analgesics

Anti Rheumatics Non Steroidal Systemic

Zix-RP Capsule

Zix-RP Capsule

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Zix-RP Capsule

Benefits of Zix-RP Capsule

Side effects of Zix-RP Capsule

How to use Zix-RP Capsule

How Zix-RP Capsule works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Zix-RP Capsule?

Can I stop taking Zix-RP Capsule when my pain is relieved?

Can the use of Zix-RP Capsule cause nausea and vomiting?

Can the use of Zix-RP Capsule cause dizziness?

Can the use of Zix-RP Capsule cause damage to kidneys?

Can I take a higher than the recommended dose of this medicine?

What is the recommended storage condition for Zix-RP Capsule?

Fact Box

Habit Forming

Therapeutic Class

References

User feedback

Patients taking Zix-RP Capsule

What are you using Zix-RP Capsule for?

How much was the improvement?

What were the side-effects while using Zix-RP Capsule?

How do you take Zix-RP Capsule?

Please rate Zix-RP Capsule on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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