Prescription Required
Store at room temperature (10-30°C)


ZITA (GRAF) 50MG/2MG TABLET is a combination medicine used in the treatment of pain due to muscle spasm. It improves the movement of muscles and provides relief from pain and discomfort associated with muscle spasms.

ZITA (GRAF) 50MG/2MG TABLET should be taken with food. This will prevent you from getting an upset stomach. You should take it regularly as advised by your doctor. Do not take more or use it for longer duration than recommended by your doctor.

Some of the common side effects on of this medicine includes nausea, vomiting, stomach pain, heartburn, diarrhea, dryness in mouth, loss of appetite, and sleepiness. If any of these side effects bother you or do not go away with time, you should let your doctor know. Your doctor may help with ways to reduce or prevent these side effects.

The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any problems with your heart, kidneys, and liver. To make sure it is safe for you, let your doctor also know all the other medicines you are taking. Pregnant and breastfeeding mothers should first consult their doctors before using the medicine.

Uses of ZITA (GRAF) Tablet

  • Pain due to muscle spasm

Benefits of ZITA (GRAF) Tablet

In Pain due to muscle spasm

ZITA (GRAF) 50MG/2MG TABLET treats pain due to muscle spasm by relaxing stiff muscles. It also reduces swelling in the muscles. Altogether, it helps in easy movement and reduces discomfort. Once you see some improvement, you can start doing therapy exercises (such as walking or breathing exercises) that will help you get your strength back more quickly.

Side effects of ZITA (GRAF) Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of ZITA (GRAF)

  • Nausea
  • Vomiting
  • Stomach pain/epigastric pain
  • Heartburn
  • Diarrhea
  • Dryness in mouth
  • Loss of appetite
  • Sleepiness

How to use ZITA (GRAF) Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. ZITA (GRAF) 50MG/2MG TABLET is to be taken with food.

How ZITA (GRAF) Tablet works

ZITA (GRAF) 50MG/2MG TABLET is a combination of two medicines: Diclofenac and Tizanidine, which relieves pain and relaxes the muscles. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). Tizanidine is a muscle relaxant. It works on the centres in the brain and spinal cord to relieve muscle stiffness or spasm and to improve pain and movement of muscles.

Safety Advice

It is unsafe to consume alcohol with ZITA (GRAF) 50MG/2MG TABLET.
ZITA (GRAF) 50MG/2MG TABLET is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
ZITA (GRAF) 50MG/2MG TABLET is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
ZITA (GRAF) 50MG/2MG TABLET may cause side effects which could affect your ability to drive.
ZITA (GRAF) 50MG/2MG TABLET may cause headaches, blurred vision, dizziness or drowsiness in some patients. This may affect your ability to drive.
ZITA (GRAF) 50MG/2MG TABLET should be used with caution in patients with kidney disease. Dose adjustment of ZITA (GRAF) 50MG/2MG TABLET may be needed. Please consult your doctor.
ZITA (GRAF) 50MG/2MG TABLET should be used with caution in patients with liver disease. Dose adjustment of ZITA (GRAF) 50MG/2MG TABLET may be needed. Please consult your doctor.
Use of ZITA (GRAF) 50MG/2MG TABLET is not advised in patients with severe liver disease. Liver function tests are recommended before the start of treatment and then on a regular basis as advised.

What if you forget to take ZITA (GRAF) Tablet?

If you miss a dose of ZITA (GRAF) 50MG/2MG TABLET, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Tizpa D Tablet
Blue Cross Laboratories Ltd
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Tolunac 50mg/2mg Tablet
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Bionac TZ 50mg/2mg Tablet
Ultramark Healthcare Pvt Ltd
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Zita 50mg/2mg Tablet
Genesis Biotech Inc
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Quick Tips

  • ZITA (GRAF) 50MG/2MG TABLET helps relieve pain and muscle spasm that may occur due to strains, sprains, and muscle injuries.
  • It is usually used along with rest and physical therapy.
  • Take it with food to avoid an upset stomach.
  • It may cause dizziness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking ZITA (GRAF) 50MG/2MG TABLET as it may cause excessive drowsiness.

Fact Box

Habit Forming
Therapeutic Class

Patient Concerns

Sir, shall I take ZITA.5omg, instead of Istavel 50mg. plz.answer soon as possible.
Dr. Kamal Rijhwani
Ya better and cheaper drug
I am taking glimpride 1/500 and Zita plus 20mg for 1 year .can I quit Zita plus
Dr. Sanjay Bhatt
Depends on your HbA1c control
Do you have any questions related to ZITA (GRAF) 50MG/2MG TABLET ?

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.


  1. Diclofenac. Rouse Boulevard, Philadelphia: Iroko Pharmaceuticals; 1998 [revised Oct. 2013]. [Accessed 02 Apr. 2019] (online) Available from:External Link
  2. Tizanidine. Ardsley, New York: Acorda Therapeutics Inc.; 1996 [revised 2013]. [Accessed 02 Apr. 20191] (online) Available from:External Link
  3. Diclofenac. Daventry, Northamptonshire: Dexcel Pharma Ltd.; 1996 [revised 20 Dec. 2017]. [Accessed 02 Apr. 2019] (online) Available from:External Link
  4. Tizanidine. Hawthorne, New York: Acorda Therapeutics Inc.; 2006]. [Accessed 02 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

8th Floor, Sarovar Complex, C.G Road, Ahmedabad 380009, Gujarat, India.
Country of Origin: India

We do not facilitate sale of this product at present


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