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Zinase-Plus Tablet


Product introduction

Zinase-Plus Tablet is a pain relieving medicine. It is used to treat pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It is also used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.

Zinase-Plus Tablet should be taken empty stomach. This will prevent you from getting an upset stomach. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for longer duration than recommended by the doctor.

The most common side effects of this medicine include nausea, vomiting, heartburn, diarrhea, stomach pain, and loss of appetite. If any of these side effects bother you or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the side effects.

Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness.


Uses of Zinase-Plus Tablet

Benefits of Zinase-Plus Tablet

In Pain relief

Zinase-Plus Tablet relieves pain, reduce swelling and ease inflammation in conditions like rheumatoid arthritis, osteoarthritis and ankylosing spondolytis. It also gives relief from muscle and back pain, toothache, or pain in the ear and throat. Taking Zinase-Plus Tablet will help in speedy recovery due to its anti-inflammatory and antioxidant properties. Take it as it is prescribed to get the most benefit. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Zinase-Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zinase-Plus

  • Heartburn
  • Diarrhea
  • Stomach pain
  • Loss of appetite
  • Nausea
  • Vomiting
  • Indigestion

How to use Zinase-Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zinase-Plus Tablet is to be taken on an empty stomach.

How Zinase-Plus Tablet works

Zinase-Plus Tablet is a combination of four medicines: Bromelain, Diclofenac, Rutoside and Trypsin Chymotrypsin. Bromelain and Trypsin Chymotrypsin are enzymes. They increase blood supply and make the body produce substances that fight pain and swelling. Diclofenac is a non-steroidal antiinflammatory drug (NSAID) which works by blocking the release of certain chemical messengers (prostaglandins) in the brain that cause pain and inflammation (redness and swelling). Rutoside is an antioxidant which protects the body from damage by chemicals (free radicals) and further reduces swelling.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Zinase-Plus Tablet
Pregnancy
CONSULT YOUR DOCTOR
Zinase-Plus Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Zinase-Plus Tablet during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Zinase-Plus Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Zinase-Plus Tablet may cause headaches, blurred vision, dizziness or drowsiness in some patients. This may affect your ability to drive.
Kidney
CAUTION
Zinase-Plus Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver
CAUTION
Zinase-Plus Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

What if you forget to take Zinase-Plus Tablet?

If you miss a dose of Zinase-Plus Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Zinase-Plus Tablet
₹14.1/Tablet
Lymed-D Tablet
Comed Chemicals Ltd
₹22.2/tablet
57% costlier
Kinetozyme-D Tablet
Systopic Laboratories Pvt Ltd
₹13/tablet
8% cheaper

Quick tips

  • You have been prescribed this combination medicine for relieving pain and inflammation.
  • Take it with food to avoid getting an upset stomach.
  • Do not take it with any other pain medicine without asking your doctor first.
  • It may change the color, consistency, and odor of your stool. This is harmless. Inform your doctor if this bothers you.
  • It may increase the severity of your condition at the start of treatment. Continue using it as prescribed by your doctor.
  • Your doctor may regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.

Fact Box

Habit Forming
No
Therapeutic Class
PAIN ANALGESICS

Patient concerns

Ear Pain suggest any medicine
Dr. Shubhra Chandan Pradhan
ENT
Take combiflam or zinase d or ibugesic plus for pain according to weight. Most probably it is ear infection. Very common in children
for body pain relief i taking dolokind - plus tablet I asking advise sir which is best for long time
Dr. Pushkar Mani
Physician
for long time no pain killer is goodfirst need to diagnose the reason of pain

User feedback


FAQs

What is Zinase-Plus Tablet used for?

This medicine is used to relieve pain, swelling, and inflammation in conditions like osteoarthritis, rheumatoid arthritis, injuries, and post-surgery recovery.

Does Zinase-Plus Tablet cure arthritis?

Arthritis is a non-curable disease but can be managed. Zinase-Plus Tablet does not cure arthritis but can relieve symptoms of arthritis-like joint pain and swelling.

Are there any special warnings regarding surgery during Zinase-Plus Tablet treatment?

Yes, stop taking Zinase-Plus Tablet at least 2 weeks before any planned surgery as it may increase the risk of bleeding during or after surgery.

Can Zinase-Plus Tablet be used by everyone?

No, people allergic to any ingredient present in the medicine, especially those allergic to pineapple, carrot, papaya, fennel, or pollens, should avoid taking Zinase-Plus Tablet.

In what health conditions Zinase-Plus Tablet should be avoided?

Zinase-Plus Tablet should be avoided or (used with caution) if you have bleeding disorders, kidney or liver problems, ulcers, infection, hematuria (blood in urine), or uncontrolled hypertension.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. ScienceDirect. Bromelain. [Accessed 18 Apr. 2019] (online) Available from:External Link
  2. Shah D, Mital K. The Role of Trypsin:Chymotrypsin in Tissue Repair. Adv Ther. 2018;35(1):31-42. [Accessed 18 Apr. 2019] (online) Available from:External Link
  3. Trypsin, Bromelain, and Rutoside. Ahmedabad, Gujarat: Torrent Pharmaceuticals Ltd.; [Accessed 03 Nov. 2025] (online).External Link

Marketer details

Name: Rapross Pharmaceuticals Pvt Ltd
Address: IInd Floor, Garg Plaza, 5 Community Centre, Sector-8, Rohini, Delhi-110085
Country of origin: India
Expires on or after: March, 2026

A licensed vendor partner from your nearest location will deliver Zinase-Plus Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

MRP151.8  7% OFF
141
Inclusive of all taxes
10.0 tablets in 1 strip
New GST benefit included in this MRP, may differ from label

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