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Zilarta-CT 40 Tablet is a medicine used to treat high blood pressure (hypertension) and lower the risk of heart attack, stroke, and kidney damage. It works by lowering blood pressure and improving blood flow, which reduces strain on the heart and helps protect vital organs such as the heart, brain, and kidneys.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 08 Jan 2026 | 04:19 PM (IST)
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Zilarta-CT 40 Tablet image
Zilarta-CT 40 Tablet image
Zilarta-CT 40 Tablet image
Zilarta-CT 40 Tablet image
Zilarta-CT 40 Tablet image
Zilarta-CT 40 Tablet image

Product introduction

Zilarta-CT 40 Tablet can be taken with or without food, but take it at the same time to get the most benefit. It should be taken with your doctor's advice. The dose and how often you take it depend on what you are taking it for. Never skip any doses and finish a full course of treatment even if you feel better. This medication mustn't be stopped suddenly without talking to the doctor, as it may worsen your symptoms.


It may cause side effects like tiredness, decreased potassium level in blood, decreased blood pressure, increased creatinine level in blood, and increased uric acid level in blood. It is advised to drink plenty of fluids while taking this medicine. It may cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Regular monitoring of blood pressure is required while taking this medicine.


Before taking this medicine, tell your doctor if you are pregnant or breastfeeding, if you have ever had any problems with your blood circulation, or have liver or kidney problems. Your doctor should also know about all other medicines you are taking, as many of these may make this medicine less effective or change the way it works.

Uses of Zilarta-CT Tablet

Benefits of Zilarta-CT Tablet

Hypertension (high blood pressure)
Zilarta-CT 40 Tablet relaxes the blood vessels so that blood can flow more easily around your body. It also increases urine output. This lowers your blood pressure and reduces your risk of having a stroke, a heart attack, or kidney problems in the future. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well. You should take it regularly as prescribed for this medicine to be most effective, even if you feel better.

Side effects of Zilarta-CT Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zilarta-CT
  • Dizziness
  • Tiredness
  • Increased uric acid level in blood
  • Decreased potassium level in blood
  • Decreased blood pressure
  • Increased creatinine level in blood

How to use Zilarta-CT Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zilarta-CT 40 Tablet may be taken with or without food.

How Zilarta-CT Tablet works

Zilarta-CT 40 Tablet is a combination of two medicines: Azilsartan medoxomil and Chlorthalidone which lower blood pressure effectively. Azilsartan medoxomil is an angiotensin receptor blocker (ARB). It works by blocking the hormone angiotensin, thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Chlorthalidone is a diuretic that removes extra water and certain electrolytes from the body. Over time, it also relaxes blood vessels and improves blood flow.

Quick tips

  • You have been prescribed Zilarta-CT 40 Tablet for the treatment of high blood pressure.
  • It can be taken with or without food.
  • Zilarta-CT 40 Tablet may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, very dry mouth, or muscle weakness.
  • It may cause dizziness. Get up slowly when rising from a sitting or lying position. 
  • Use of Zilarta-CT 40 Tablet during pregnancy or breastfeeding is unsafe.
  • It may also decrease the risk of stroke and heart attacks.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Zilarta-CT 40 Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Zilarta-CT 40 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.
Driving

Driving

UNSAFE
Zilarta-CT 40 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Zilarta-CT 40 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Zilarta-CT 40 Tablet is not recommended in these patients.
Liver

Liver

CAUTION
Zilarta-CT 40 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Zilarta-CT 40 Tablet is not recommended in patients with severe liver disease.

Frequently asked questions

Zilarta-CT 40 Tablet is used to lower high blood pressure (hypertension). Zilarta-CT 40 Tablet combines azilsartan medoxomil, which relaxes blood vessels, and chlorthalidone, which helps the body remove excess salt and water. Together, they help reduce the risk of strokes and heart attacks.
Zilarta-CT 40 Tablet should not be used by people if they cannot pass urine (a condition called anuria). Zilarta-CT 40 Tablet also should not be taken with aliskiren-containing medicines if you have diabetes. Always tell your doctor about your full medical history before starting treatment.
If you have low salt or fluid levels, Zilarta-CT 40 Tablet may cause your blood pressure to drop too much. Zilarta-CT 40 Tablet may also worsen kidney problems in people with narrowed kidney arteries. Your doctor may run blood and urine tests to monitor kidney function, electrolytes.
Yes, in some patients, especially those with kidney artery narrowing or pre-existing kidney disease, Zilarta-CT 40 Tablet can cause worsening kidney function or even kidney failure. Regular monitoring is recommended.
Yes, Zilarta-CT 40 Tablet can affect sodium, potassium, and other electrolytes in the blood. Low potassium or sodium, and sometimes high calcium or uric acid, may occur. Your doctor will check your blood tests regularly.
Serious side effects of Zilarta-CT 40 Tablet include very low blood pressure, kidney failure, electrolyte imbalances, high uric acid (which can cause gout), and rare, severe allergic reactions. Seek immediate help if you experience swelling of the face, difficulty breathing, or severe weakness.
Yes, chlorthalidone, one of the components present in Zilarta-CT 40 Tablet, can raise uric acid levels in the blood, which may lead to gout attacks in some people. If you have gout, discuss this risk with your doctor.
High blood pressure is usually a lifelong condition. Zilarta-CT 40 Tablet is generally taken long-term to keep blood pressure under control, unless your doctor advises switching or stopping.
Uncontrolled high blood pressure increases the risk of serious health problems such as stroke, heart attack, kidney failure, and heart disease. Zilarta-CT 40 Tablet helps lower blood pressure, reduces these risks.

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User feedback

Once A Day
100%
Hypertension (high blood pressure)
83%
Others
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Average
100%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Micro Labs Ltd
Address: 27, RACE COURSE ROAD, BANGALORE-560 001, INDIA || Mamring Namthang Road, Namchi-737132, Sikkim || Plot no 37 (CA) 147-151 , 279-281 ,Ground Mezzanine , 1st & 2nd Floor K.I.A.D.B JIgani Bomasandra , Link Road, Bangalore - 562106, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Zilarta-CT 40 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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