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Zentocuf-DX Syrup

Dextromethorphan Hydrobromide (10mg)+ Chlorpheniramine Maleate (4mg)+ Phenylephrine (5mg)+ Guaifenesin (100mg)+ Menthol (2.5mg)

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Zentocuf-DX Syrup is a medicine used to treat dry cough. It works by suppressing the cough reflex in the brain. It also thins the mucus and makes it easier to cough out. Additionally, it relieves allergy symptoms like watery eyes, sneezing, a runny nose, and throat irritation.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 10 Oct 2026 | 01:03 AM (IST)

₹65.3 MRP ₹7513% off

(Inclusive of applicable taxes)

Gurgaon

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General Information

Contains

Dextromethorphan Hydrobromide (10mg)+ Chlorpheniramine Maleate (4mg)+ Phenylephrine (5mg)+ Guaifenesin (100mg)+ Menthol (2.5mg)

Marketer

Iva Healthcare Pvt. Ltd.

The content is shown in English

Product introduction

Zentocuf-DX Syrup may be taken with or without food. Take it in the dose and duration advised by the doctor. Continue taking the medicine for as long as your doctor recommends. If you stop treatment too early, your symptoms may come back, and your condition may worsen. Let your doctor know about all other medications you are taking, as some may affect, or be affected by, this medicine.

There are limited data on the common side effects of Zentocuf-DX Syrup. However, if you experience any symptoms that you think are caused by the medicine, let your doctor know. Avoid drinking alcohol while taking this medicine, as it can cause excessive sleepiness.

Never support self-medication or recommend your medicine to another person. It is beneficial to have plenty of fluids while taking this medication. Before you start taking this medicine, it is important to inform your doctor if you are suffering from any lung, liver, or kidney disease. You should also tell your doctor if you are pregnant or planning a pregnancy.

Note: As per the Ministry of Health and Family Welfare, Zentocuf-DX Syrup should not be used in children below four years of age.

Uses of Zentocuf-DX Syrup

Treatment of Cough

Benefits of Zentocuf-DX Syrup

Treatment of Cough
Cough can result from infections, allergies, or throat irritation and is often associated with congestion, mucus buildup, or a runny nose. Zentocuf-DX Syrup helps by calming throat irritation, reducing nasal blockage, controlling allergy-related symptoms like sneezing or runny nose, loosening mucus for easy clearance, and soothing the throat. This medicine provides all-around relief, making breathing easier and improving comfort during recovery.

Side effects of Zentocuf-DX Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zentocuf-DX

Limited data available

How to use Zentocuf-DX Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Zentocuf-DX Syrup may be taken with or without food.

How Zentocuf-DX Syrup works

Zentocuf-DX Syrup is a combination of five medicines: Dextromethorphan Hydrobromide, Chlorpheniramine Maleate, Phenylephrine, Guaifenesin, and Menthol. Dextromethorphan Hydrobromide is an antitussive (cough suppressants). It suppresses cough by reducing the activity of the cough centre in the brain. Chlorpheniramine Maleate is an anti-allergic medication. When your body is exposed to an allergen (pollen, animal dander, house dust etc.), it produces a chemical called histamine. This causes watery eyes, runny or blocked nose, sneezing, skin rashes, itching etc. Chlorpheniramine Maleate works by blocking the action of histamine, thereby relieving these symptoms. Phenylephrine is a decongestant which narrows the small blood vessels providing relief from congestion or stuffiness in the nose. Guaifenesin works by decreasing the stickiness of mucus (phlegm) and helps in its removal from the airways. Menthol has mild cooling and decongestant properties that help soothe the cough and ease congestion in the lungs.

Quick tips

Avoid lying down immediately after taking Zentocuf-DX Syrup to help the medicine go down smoothly.
Avoid consuming alcohol as it can worsen drowsiness caused by this medicine.
Drink plenty of fluids to help loosen mucus and clear your chest faster.
Do not drive or do anything that needs focus if you feel sleepy after taking it.
Check other cold or cough medicines before taking them with Zentocuf-DX Syrup to avoid accidentally taking the same ingredients again.

Safety advice

Alcohol

UNSAFE

Do not drink alcohol while you are taking this medicine. Zentocuf-DX Syrup may cause excessive drowsiness when taken with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Zentocuf-DX Syrup during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Zentocuf-DX Syrup may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Zentocuf-DX Syrup may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Zentocuf-DX Syrup should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Zentocuf-DX Syrup should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Frequently asked questions

What is Zentocuf-DX Syrup used for?

Zentocuf-DX Syrup is used to relieve symptoms of the common cold, flu, allergies, and upper respiratory tract infections. It helps manage cough, nasal congestion, runny nose, sneezing, and throat irritation, and helps loosen mucus (phlegm) for easier breathing.

What precautions should I take before using Zentocuf-DX Syrup?

Tell your doctor if you have high blood pressure, heart disease, diabetes, thyroid problems, glaucoma, prostate enlargement, liver/kidney disease, asthma, or chronic cough, or if you are pregnant or breastfeeding.

Who should not use Zentocuf-DX Syrup?

Individuals should not use Zentocuf-DX Syrup if they are allergic to any ingredients, have high blood pressure or heart disease, glaucoma, or urinary retention, or have taken MAO inhibitors (certain antidepressants) within the last 14 days. Children under four years old should not use this medication without a doctor's advice.

Are there any serious side effects of Zentocuf-DX Syrup I should watch out for?

The serious side effects of Zentocuf-DX Syrup include rapid or irregular heartbeat, severe allergic reactions (rash, swelling, and trouble breathing), confusion, hallucinations, seizures, or chest pain. If any of these appear, seek medical attention immediately.

What special warnings should I be aware of during Zentocuf-DX Syrup treatment?

During Zentocuf-DX Syrup treatment, do not drive, use machinery, or perform tasks requiring alertness if you feel drowsy. Avoid alcohol, as it can increase sedative effects. Do not use this medicine for longer than recommended or to make a child sleepy.

Fact Box

Habit Forming

Therapeutic Class

RESPIRATORY

References

Bateman MT Jr, Brunton S, Wright WL. Guaifenesin and dextromethorphan for management of cough and mucus-related cold symptoms in adults: a narrative literature review. Postgrad Med. 2025 Nov;137(8):741-755. [Accessed 03 Feb. 2026]. Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Iva Healthcare Pvt. Ltd.
Address: Iva Healthcare Private Limited, Manish Bansal(Director), Plot No. 400, Industrial Area, Phase 1, Panchkula - 134113, Haryana, India

Vendor Details

Country of origin: India

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Antitussives Without Codeine

Zentocuf-DX Syrup

Zentocuf-DX Syrup

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General Information

Contains

Marketer

Product introduction

Uses of Zentocuf-DX Syrup

Benefits of Zentocuf-DX Syrup

Side effects of Zentocuf-DX Syrup

How to use Zentocuf-DX Syrup

How Zentocuf-DX Syrup works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Zentocuf-DX Syrup used for?

What precautions should I take before using Zentocuf-DX Syrup?

Who should not use Zentocuf-DX Syrup?

Are there any serious side effects of Zentocuf-DX Syrup I should watch out for?

What special warnings should I be aware of during Zentocuf-DX Syrup treatment?

Fact Box

Habit Forming

Therapeutic Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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