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Last updated on:
19 Dec 2018 | 12:37 PM (IST)
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Zedonac MR 250mg/50mg/500mg Tablet


Uses of Zedonac MR Tablet

Zedonac MR 250mg/50mg/500mg Tablet is used for pain due to muscle spasm.

Zedonac MR Tablet side effects

  • Nausea
  • Vomiting
  • Heartburn
  • Stomach pain
  • Diarrhea
  • Loss of appetite
  • Dryness in mouth
  • Weakness
  • Sleepiness

How to use Zedonac MR Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zedonac MR 250mg/50mg/500mg Tablet is to be taken with food.
This will help to avoid acidity and heartburn.

How Zedonac MR Tablet works

Zedonac MR 250mg/50mg/500mg Tablet is a combination of a muscle relaxant (Chlorzoxazone) and two pain relieving medicines (Diclofenac and Paracetamol/Acetaminophen). The muscle relaxant works on the centers in the brain and spinal cord to relieve muscle stiffness or spasm, thereby improving movement of muscles. The pain relieving medicines work by blocking the release of certain chemical messengers in the brain that cause pain and inflammation (redness and swelling).

Zedonac MR Tablet related warnings

Taking Chlorzoxazone+Diclofenac+Paracetamol/Acetaminophen with alcohol can cause liver damage.
Zedonac MR 250mg/50mg/500mg Tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
No information is available on the use of Zedonac MR 250mg/50mg/500mg Tablet during lactation. Please consult your doctor.
Zedonac MR 250mg/50mg/500mg Tablet may cause side effects which could affect your ability to drive.
Zedonac MR 250mg/50mg/500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Zedonac MR 250mg/50mg/500mg Tablet may be needed. Please consult your doctor.
Zedonac MR 250mg/50mg/500mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Zedonac MR 250mg/50mg/500mg Tablet may be needed. Please consult your doctor.
However, the use of Zedonac MR 250mg/50mg/500mg Tablet is not recommended in patients with severe liver disease and active liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Zedonac MR 250mg/50mg/500mg Tablet
Intagesic-MR Tablet
Intas Pharmaceuticals Ltd
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Minidolo Tablet
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Oronac MR Tablet
Embiotic Laboratories Pvt Ltd
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Infanil MR Tablet
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Pentagesic MR Tablet
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Expert Advice

  • You have been prescribed Zedonac MR 250mg/50mg/500mg Tablet to relieve pain due to muscle spasm.
  • This medicine is most effective when taken along with proper rest and physical therapy.
  • Avoid consuming alcohol when taking Zedonac MR 250mg/50mg/500mg Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
  • Older adults may have increased drowsiness, confusion, and higher risk of falling as a result of taking Zedonac MR 250mg/50mg/500mg Tablet.
  • Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first. 

Patient Concerns

Questions Related to Zedonac MR

1) Am I really suffering from diabetes. I am daily doing Ramdev baba Yoga for 1 - 1/30 Hrs 2) I am normal , May I stop Tab Glycomet 500 ? 3) ECG is abnormal but 2D eco is normal. What is a problem? 4) Why Doctor is asking me to take daily Cap. BecoZinc forever. May I stop or continue? 5) I am suffering from Neck spondilites . 6) I feel giddiness, so doctor starts this medicine and asked to take forever for long time May I continue or what ?Plz give me second opinion.
Dr. Sfurti Mann
Diabetes Specialist
Your HbA1c levels will ascertain your diabetes control. You must continue glycometSR. It's dose may even beFor giddiness you may take stemetil MD tab sos and pantop DSR before breakfast
I m cocieved running 9 month n my date of issue is on first week of june.but i m having swelling on foot
Dr. Suman Rao
Get your BP, serum proteins and kidney function test done. If all are fine then there is nothing to worry about.
Do you have any questions related to Zedonac MR 250mg/50mg/500mg Tablet?


Q. What is Zedonac MR?

Zedonac MR is a combination of three medicines: Diclofenac, Paracetamol, and Chlorzoxazone. This medication helps in relieving muscle pain. Chlorzoxazone is a muscle relaxant which works by acting on the central nervous system. Diclofenac and Paracetamol work by lowering the chemical substance (prostaglandins) in the body that causes pain and inflammation.

Q. Is it safe to use Zedonac MR?

Zedonac MR is safe for most of the patients. However, in some patients it may cause common side effects like nausea, vomiting, heartburn, stomach pain, diarrhea, loss of appetite, dryness in the mouth, weakness, sleepiness and other uncommon or rare side effects. Inform your doctor as soon as possible if you experience any persistent problem due to the medication.

Q. Can I stop taking Zedonac MR when my pain is relieved?

Zedonac MR should be continued if advised for a specific time duration by your doctor. However, it can be discontinued if you are using it for short-term pain relief.

Q. Can the use of Zedonac MR cause nausea and vomiting?

Yes, the use of Zedonac MR can cause nausea and vomiting. In case, you experience nausea while taking this medicine, take it with milk, food or with antacids. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to your doctor.

Q. Can the use of Zedonac MR cause dizziness?

Yes, the use of Zedonac MR can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for sometime and resume once you feel better.

Q. Can the use of Zedonac MR cause damage to kidneys?

Yes, the long-term use of Zedonac MR can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protect them from damage. Use of painkillers lowers the levels of prostaglandins in the body leading to kidney damage on long-term use. Use of painkillers is not recommended to patients with underlying kidney disease.

Q. Can I take a higher than the recommended dose of this medicine?

No, taking a higher than the recommended dose of Zedonac MR can increase the risks of side effects. If you are experiencing increased severity of pain or if the pain is not relieved by the recommended doses, please consult your doctor for re-evaluation.

Q. What are the recommended storage conditions for Zedonac MR?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
The medicine details are for information purpose only. Consult a doctor before taking any medicine.
Manufacturer/Marketer Address
Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
One of the following licensed pharmacy from the nearest location will deliver Zedonac MR 250mg/50mg/500mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
10 tablets in 1 strip
Best Price ₹43.2
20% OFF
Use Coupon HEALTH1020 during checkout