Xprab Vaccine

Prescription Required
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.
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Introduction

Xprab Vaccine is given to people who are at higher risk of coming in contact with rabies like veterinarians. It is also given to people after an animal bite if the animal could have rabies. If the vaccine is given immediately and appropriately, it is 100 percent effective.

Xprab Vaccine is given by injection by a doctor or nurse. It is administered post thorough washing (for about 15 minutes, with soap and copious amounts of water) of all bite wounds as early as possible. The sooner treatment is begun after exposure, the better. Post-exposure anti-rabies vaccination should always include administration of both Immunoglobulin and vaccine, with the exception of persons who have previously received complete vaccination regimens. It is very very important to complete the course of the vaccine to prevent this fatal disease.

The most common side effects include pain, joint pain, vaccination site redness as well as swelling. They do not normally last very long. Sitting or lying down can sometimes help. Consult your doctor if any of the side effects persist or worry you.

Before having the injection, you should tell your doctor if you have ever had an allergic reaction to a vaccine. Some other medicines may react with the rabies vaccine, so let your doctor know about all the medicine you are taking as well.

Uses of Xprab Injection

Benefits of Xprab Injection

In Prevention of Rabies

Rabies is a serious disease caused by the rabies virus. It is transmitted through the saliva of infected animals. Xprab Vaccine is given to people who are at higher risk of coming in contact with rabies virus like veterinarians, animal keepers, hunters, butchers, personnel in rabies research laboratories, etc., or those with a prior visit to areas in which rabies is endemic. The vaccine helps develop immunity by forming antibodies, that protect against infection caused by viruses. Vaccination can also prevent the disease if it is given to a person after they have been exposed. It is to be administered only by or under the supervision of your doctor. You should not self-administer this medicine.

Side effects of Xprab Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Xprab

  • Pain
  • Joint pain
  • Injection site redness
  • Injection site swelling
  • Swelling of lymph nodes

How to use Xprab Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Xprab Injection works

Xprab Vaccine is an inactivated vaccine. It helps develop immunity by forming antibodies, which are proteins that protect against infection caused by viruses.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Xprab Vaccine. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Xprab Vaccine is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Xprab Vaccine is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Xprab Vaccine alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Xprab Vaccine in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Xprab Vaccine in patients with liver disease. Please consult your doctor.

What if you forget to take Xprab Injection?

If you miss a dose of Xprab Vaccine, please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Xprab Vaccine helps prevent rabies.
  • It is given as an injection into the muscle of the upper arm.
  • If you are at risk of being bitten, the vaccine is given as a course of three injections on days 0, 7 and 28. A booster dose is needed one year after completing this course.
  • If you have been immunized against rabies and bitten by an animal suspected of having rabies, two doses of the vaccine are needed, first on the day of the bite and second on day 3 after the bite.
  • If you have not been immunized against rabies and bitten by an animal suspected of having rabies, the first injection of rabies vaccine should be given as soon as possible after the bite. This is followed by four further doses on days 3, 7, 14 and 30.
  • Do not take Xprab Vaccine if you have a weak immune system.

Fact Box

Chemical Class
Vaccines
Habit Forming
No
Therapeutic Class
VACCINES
Action Class
Killed vaccine

Interaction with drugs

Taking Xprab with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Healgraft, Graftide-M, Ceptimmun
LIFE-THREATENING
Brand(s): Thioprinz, Lazorin, Azarid
SERIOUS
Brand(s): Oncomide, Cyclomet, Cyphos
SERIOUS
Brand(s): Empurine
SERIOUS

Patient concerns

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Prevention of acene and pimples
Dr. Manju Singh
Homeopathy
Wash acne-prone areas only twice a day. Washing removes excess oil and dead skin cells. But too much washing can irritate the skin. Wash affected areas with a gentle cleanser and use oil-free, water-based skin care products. Use non- oily makeup. Choose oil-free cosmetics that won't clog pores. Remove makeup before going to bed. Going to sleep with cosmetics on your skin can clog your pores. Avoid touching or picking at the problem areas. Doing so can trigger more acne. Always use a clean towel or cloth to wipe your face. Always keep your hands clean and wash them regularly so that you may not touch your skin with dirty hands.
Medicine for prevention of pregnancy?
Dr. Pranay Gandhi
Sexology
i pill 1 tablet within 72 hrs of unprotected sex
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User feedback


FAQs

Q. How does rabies spread?

The rabies virus is transmitted in the saliva of infected animals. People usually become infected with the virus if they get bitten by an infected animal. However, any contact with the saliva of an infected animal (alive or dead) can potentially lead to rabies infection if the person has an opening in the skin or the saliva gets into their eyes, nose or mouth.

Q. Is rabies preventable?

Rabies is a 100% preventable disease. Proper wound management and simultaneous administration of Xprab Vaccine combined with rabies immunoglobulin (RIG) is considered invariably effective in preventing rabies, even after high-risk exposure.

Q. What are the symptoms of rabies?

The rabies virus attacks the nervous system (brain and spinal cord). The first symptoms of rabies are similar to a flu-like illness which can be identified as fever, headache and general discomfort. Within days, the disease can progress to symptoms such as anxiety, confusion, agitation, abnormal behavior, delirium and hallucinations.

Q. Who should get this vaccine?

Rabies vaccine is recommended for persons in high-risk occupational groups, such as veterinarians and their staff, animal handlers, rabies researchers and certain laboratory workers. International travelers who are likely to come in contact with animals in areas where cases of dog rabies are common. People should remain cautious and must get Xprab Vaccine, especially if they will have limited access to appropriate medical care in such areas.

Q. Can a pregnant woman receive Xprab Vaccine if exposed to rabies?

Yes, Xprab Vaccine can be taken by a pregnant woman. Cases of any fetal abnormalities in pregnant women have not been reported with the use of Xprab Vaccine. The doctor may even suggest routine pre-exposure vaccination against rabies if the risk of exposure is high.

Q. What are the side effects of Xprab Vaccine?

Most of the side effects of Xprab Vaccine are mild, such as soreness and redness at the injection site. Moderate problems, including hives, pain in the joints and fever, are possible in a small percentage of patients (6%) who are given booster doses.

Q. Who should not receive Xprab Vaccine?

Xprab Vaccine is not recommended for routine use in the general population. It should not be used if a person is moderately or severely ill. If you have any doubts, consult your doctor.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Sinha A, Singh S. Immunization and Immunodeficiency. In: Paul VK, Bagga A, editors. Ghai Essential Pediatrics. 8th ed. New Delhi: CBS Publisher's & Distributors Pvt Ltd.; 2013. pp. 202-203.
  2. Rabipur [Inactivated rabies virus]. Ankleshwar, Gujarat: Chiron Behring Vaccines Pvt. Ltd.; 2002. [Accessed 15 Jul. 2019] (online) Available from: External Link
  3. Imovax Rabies Vaccine. Swiftwater, PA: Sanofi; 2013. [Accessed 04 Apr. 2019] (online) Available from:External Link
  4. Rabies Vaccine. Swiftwater PA: Sanofi; 2013. [Accessed 04 Apr. 2019] (online) Available from:External Link
  5. Rabipur Ampoule [Rabies Vaccine bp]. Uxbridge, Middlesex: GlaxoSmithKline UK; 2003 [revised 7 May 2018]. [Accessed 15 Jul. 2019] (online) Available from: External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 03 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer address

90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001
Country of origin: India

Expires on or after: July, 2023

A licensed vendor partner from your nearest location will deliver Xprab Vaccine. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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0.5 ml in 1 vial
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