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Wayfenac Spray is a medicine applied topically to relieve pain. It works by first cooling the skin then warming it up. This cooling and warming up action improves blood circulation and distracts the patient from pain. It also blocks the release of certain chemical messengers that cause pain and swelling.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 25 Nov 2025 | 03:07 PM (IST)
₹214 MRP ₹242.8112% off 
 
 
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Wayfenac Spray image
Wayfenac Spray image

Product introduction

Wayfenac Spray is only meant for external use and should be used strictly as advised by your doctor. A thin layer of the medicine should be rubbed into the affected areas with clean and dry hands. Avoid getting in contact with your eyes, nose, or mouth and avoid applying it on wounded or damaged skin. In case of accidental contact, rinse it with plenty of cold water.

Use of this medicine may cause common side effects such as burning or stinging sensation, irritation, itching, and redness at the site of application in some people. Usually, the side effects will slowly go away as your body gets used to it. If they are severe or do not go away, you should let your doctor know.

Although medicines used on the skin are not normally affected by other medicines, you should let your doctor know if you are taking any other medicine. You should also let your doctor know if you have any medical conditions or disorders to make sure it is safe for you. Ask your doctor for advice if you are pregnant or breastfeeding.

Uses of Wayfenac Spray

Benefits of Wayfenac Spray

Pain relief
Wayfenac Spray gives fast relief from pain and swelling in conditions like rheumatoid arthritis, osteoarthritis, muscle and back pain by creating a cooling-warming effect. It works by causing the skin to feel cool and then warm. These feelings on the skin distract you from feeling the pain in your muscles and joints. Altogether, it will help you do your daily activities without much problem. Apply a thin layer of the medicine to the affected area no more than 3 to 4 times a day and rub in gently and thoroughly.

Side effects of Wayfenac Spray

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Wayfenac
  • Application site reactions (burning, irritation, itching and redness)

How to use Wayfenac Spray

Hold the container with the extension tube aimed at the area of application. To spray, press the button. Allow a 2 second gap between two consecutive sprays. Use it as advised by your doctor or also check the label for directions before use.

How Wayfenac Spray works

Wayfenac Spray is a combination of three medicines: Diclofenac, Methyl salicylate and Menthol which relieve pain. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers in the brain that cause pain and inflammation (redness and swelling). Methyl salicylate and Menthol are topical analgesics (pain relievers). They work by first cooling the skin then warming it up. This cooling and warming up action improves blood circulation and distracts from feeling the pain.

Quick tips

  • You have been prescribed Wayfenac Spray to get relief from pain.
  • Apply 2-3 times daily or as prescribed by the doctor.
  • Do not apply to large areas of skin or near sensitive areas such as private parts or on broken or injured skin.
  • Avoid contact with the eyes, mouth, nose and rinse thoroughly in case of accidental contact or seek medical help in case of swallowing.
  • Avoid applying Wayfenac Spray right after bathing or shaving. Using this medication on freshly shaved skin areas can cause severe skin irritation.
  • Consult your doctor if you get excessive skin irritation or other unwanted effects.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Wayfenac Spray is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Wayfenac Spray during breastfeeding is not available. Please consult your doctor.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Frequently asked questions

Wayfenac Spray is used to relieve muscle pain, joint pain, back pain, sprains, and inflammation. It works by reducing swelling, soothing soreness, and providing a cooling effect for quick comfort.
Individuals should not use Wayfenac Spray if they are allergic to diclofenac, aspirin, menthol, or any nonsteroidal anti-inflammatory drugs (NSAIDs). People with asthma, stomach ulcers, severe kidney or liver problems, or aspirin sensitivity should also avoid it.
Yes, although rare, Wayfenac Spray may cause serious allergic reactions. Warning signs include swelling of the face or throat, difficulty breathing, severe rash, or dizziness. If this happens, stop using the medicine and get medical help immediately.
Serious side effects of Wayfenac Spray may include severe skin irritation, blistering, unexplained bleeding, black stools, chest pain, or breathing problems. These are rare but require urgent medical attention.

Fact Box

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Smartway Wellness
Address: 401, Times Square Grand, Nr. Sattva Vikas School, Sindhubhavan Main Road, Thaltej, Ahmedabad, Guj (380059)

Vendor Details

Country of origin: India
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